NewsMakers
Can you sleep with contact lenses in?
Do not wear contact lenses for at least one full day to allow your eyes to heal. Contact your eye care provider immediately if you notice any symptoms of infection or discomfort.
Contact lenses are wonderful because they provide a near-normal vision experience without corrective glasses. But they can be easily forgotten. When preparing to sleep, even for a nap, is not the time to forget about them.
To help contact lens wearers understand the implications of sleeping in their lenses, Lens.com published an informative guide.
Can you sleep in contact lenses?
Did you know that sleeping with regular contact lenses can result in severe infection and put you at risk for vision loss? Some contact lenses, like extended wear contacts, are meant to be worn overnight. However, many are not. You can only sleep in contact lenses designed for overnight wear, such as Acuvue Oasys with Hydraclear Plus, which is approved for up to six consecutive nights of wear.
Contact lenses are medical devices that require proper care and handling to avoid severe side effects. Yet, as little as two percent of contact lens wearers report following their eye care provider’s instructions.
What happens if you sleep with contacts lenses in?
It’s important to know the implications of sleeping in contact lenses not designed for extended wear or if they are left in too long.
- Eye Infections. Eye infections are the most significant risk of sleeping in contact lenses not approved for extended wear. When you sleep in your contact lenses, your risk of contracting eye infections increases six to eight times. The most common infection is called conjunctivitis or pink eye. This common eye infection is mainly caused by wearing contact lenses overnight, but it can also be caused by allergies or coming into contact with someone who has it. Sleeping with your contact lenses makes you more susceptible to pink eye because your contact lenses can leave microscopic tears on your cornea, thus increasing your odds of bacteria entering and getting trapped in your eye and leading to infection.
- Hypoxia. Oxygen is essential for the healthy function of your eyes. There are no blood vessels in your corneas (the clear tissue at the front and center of your eye), which means they get their oxygen directly from the air. Contact lenses reduce the amount of oxygen that reaches your cornea. Now imagine sleeping with contact lenses in your eyes. With our eyes shut and contact lenses, the amount of oxygen is greatly restricted and can lead to hypoxia of the eye. This extreme oxygen deprivation can cause warping, scarring, pain, and vision loss.
- Corneal Ulcers. If your contact lenses are not taken out and cared for properly, you may cause so much irritation that you cause corneal ulcers, or open sores on the cornea, to form. These ulcers can even become so severe that they require a corneal transplant using donor tissue. Those who sleep with contact lenses not approved for extended wear are five times more likely to develop corneal infections, permanently damaging their vision.
- Contact Lens-induced Acute Red Eye (CLARE). Tight Lens Syndrome or Contact Lens Overwear Syndrome is usually marked by light sensitivity, redness, tearing, and decreased vision. When a contact lens fits too tightly, it will stick to the cornea like a suction cup, and this will cause the cornea to swell. If not treated, You could be at risk for a severe infection that can cause a corneal ulcer leading to permanent scarring and vision loss. Contact lenses are like tiny sponges; they expand when they are moist and shrink when they dry out.
- Giant Papillary Conjunctivitis (GPC). Wearing your contact lenses for prolonged periods or overnight can cause bumps to form underneath your eyelids called GPCs. If you wear your contacts while you sleep, you have the greatest chance of experiencing this unpleasant condition. These bumps can result in your contact lenses no longer fitting properly. If this happens, your eye care provider may ask you to stop wearing your contact lenses for a week and see if your symptoms subside.
Why does sleeping with contact lenses increase your risk of an eye infection?
After wearing your lenses all day long, napping or falling asleep means your lenses have collected pollutants, bacteria, and dirt that could increase your risk of complications. As your eye and contact lens becomes dehydrated in your sleep, the lens starts to shrink and tear at your cornea, and these microscopic tears allow an entry point for bacteria to get into your eye. Sleeping in contact lenses increases your chance of getting an eye infection six to eight times.
What to do if you accidentally sleep with contact lenses in?
Attempt to remove your contact lenses as soon as you’ve discovered that you’ve fallen asleep with them in your eyes. Make sure you follow your standard hygiene practices. If you cannot remove them easily, stop! Tugging at a dehydrated lens attached to your eye can cause tearing. Instead, place several drops of sterile contact solution on your eyes or lubricating drops. Blink several times. And try again.
After successfully removing your contact lenses, pay attention to how your eyes feel. Do not wear contact lenses for at least one full day to allow your eyes to heal. Contact your eye care provider immediately if you notice any symptoms of infection or discomfort. The signs of an eye infection are blurred vision, redness, excessive watering, and discharge from the eye. If you think you have an eye infection, your eye doctor may want to test your contact lenses, so be sure to take those with you when you visit.
Always practice safe habits following the guidelines your eye care professional provided and check with them whenever you’re in doubt.
If you are guilty of sleeping or taking naps in your contact lenses, it’s time to change your eye care routine. You may want to consider taking out your contact lenses after dinner and switching to eyeglasses so you don’t forget them before bedtime. If you are a fan of naps or have an unpredictable schedule, visit your eye care provider and ask if extended-wear contact lenses are for you. You can browse all the contact lenses you sleep in at Lens.com.
Why are some contact lenses FDA-approved for overnight or extended wear while others aren’t?
The simplest reason why not all contact lenses are FDA-approved for overnight wear is that contact lens manufacturers have to apply for FDA approval. Applying for FDA approval is a lengthy process that requires submitting studies and research documents and passing clinical trials. If a manufacturer wants FDA approval, they’d have to spend considerable time and resources.
Another reason is that contact lenses designed for overnight wear are made of thinner material compared to daily wear contact lenses.
Many contact lens brands that are FDA-approved for overnight wear are made with silicone hydrogel, which is significantly more breathable than standard hydrogel. Silicone hydrogel allows for much better oxygen transmissibility, which is essential when wearing contact lenses for extended periods.
Which contact lenses can you sleep in?
You can only sleep in contact lenses that are designed for overnight wear. Popular contact lenses rated for overnight usage include:
- Acuvue Oasys with Hydraclear Plus can be worn daily for two weeks or continuously for up to six nights and seven days, after which they must be removed, disposed of, and replaced with a new pair of lenses. These contact lenses feature Acuvue’s innovative Hydraclear Plus. Inspired by how the eye’s tear film works, this wetting agent keeps the contacts wet and smooth for all-day comfort. These contacts block more than 99 percent of UVB and 95 percent of UVA rays – some of the highest levels you’ll find on the market today.
- AirOptix plus HydraGlyde combines two unique technologies into one lens: SmartShield Technology and HydraGlyde Moisture Matrix technology. SmartShield Technology creates an ultra-thin protective layer to help shield your lenses from deposits and provides long-lasting comfort. HydraGlyde Moisture Matrix, on the other hand, attracts and maintains surface moisture on the lens for up to 16 hours. SmartShield Technology and HydraGlyde Moisture Matrix technology make Air Optix plus HydraGlyde very comfortable.
- Biofinity contact lenses bring a remarkable balance of comfort and breathability in a monthly disposable lens. They are FDA-approved for extended wear, meaning they can be worn continuously for up to six nights and seven days before they need to be replaced. These contacts feature CooperVision’s patented Aquaform® Technology, which locks in water so you can enjoy all-day comfort. They also have smooth, rounded edges, enhancing comfort by minimizing interaction between your contact lenses and eyelids.
- PureVision 2 HD contact lenses are another popular brand rated for night and day wear. Featuring Bausch + Lomb’s innovative High Definition™ Optics, these contact lenses help you see enhanced contrast, sharper details, and reduced glare, even in low light conditions. They reduce halos and give a crisp, clear vision while using digital devices or in low-light conditions. They’re made of a silicone hydrogel lens material that allows plenty of oxygen to reach your eyes, which they need to stay white and healthy.
Curious to see all the contact lenses you can sleep in? Visit Lens.com to learn more.
The lenses above have been approved by the FDA for use while asleep. If you already wear these contact lenses, ask your eye care provider before using contacts during sleep. Each individual’s eye health is different and your eye care provider needs to evaluate the overall health of your eye before approving overnight use.
Can you nap while wearing contact lenses?
Generally, no, you should not nap or sleep with contact lenses. This applies to all contact lens brands and types, unless specified. Falling asleep with your contact lenses could lead to infection and irritation. While modern soft contact lenses have incredible technology to ensure enough oxygen passes through the lenses in daily wear, having your eyes closed while you sleep reduces available oxygen and prevents tears from washing your eye under the contact lenses. This can potentially cause problems to your eyes through hypoxia of the eyes unless you use specific lenses designed for extended wear, as directed by your eye care professional.
Everyone faces different challenges when getting through each day, but some days are occasionally a tad more exhausting than others. Whether you are a new parent, finishing up work for a deadline, studying for an important exam, or going through health issues that keep you lethargic all day long, there’s one thing we can all agree on, and that is a nap. Studies have shown that naps boost productivity by improving alertness, performance, and mood.
Rather than avoid taking naps, consider talking to your doctor about changing your prescription to an extended-wear contact lens.
What if I fall asleep with the contact lenses for just 10 minutes?
The duration does make a difference, but it is not the only factor to consider. In general, the more time spent sleeping in contact lenses, the greater the risk that you will develop symptoms of infection or inflammation and suffer from the more severe consequences. For example, if you sometimes fall asleep during your work transit or take naps between 10 and 40 minutes long, you are likely not exposing yourself to any long-term health-related risks. You might, however, still experience blurred vision and dry eyes for a short period. If you’re asleep for an extended period of one or more hours, then your contact lenses can dry up in your eyes, which can lead to discomfort or a scratching sensation in your eyes when you open them.
The type of contact lenses you wear matters, too. Silicone hydrogel lenses allow more oxygen to the cornea, so your eyes won’t get sore. On the other hand, hydrogel lenses might cause some redness, irritation, and burning when you wake up– which could even damage your cornea. With shorter naps, these issues are less likely to occur.
The state your eyes are in before falling asleep also matters. If you have been using your contacts only for a few hours before going to bed, then there is a lower risk of your eyes getting irritated than if you have been wearing them all day. This is because contact lenses accumulate dirt and dust, such as when worn for extended periods or throughout the day. However, if you fall asleep with your contacts in the evening and stay in your eyes all night, this is more problematic.
How do you wear contact lenses safely?
Your eye health is just too important to take a chance. Consider speaking with your eye care professional about switching to contact lenses approved for extended wear when in doubt.
If you’ve accidentally slept in your contact lenses for brief periods or rarely, here are tips to help:
- Attempt to remove your contact lenses as soon as you realize you’ve slept in them. But do not sidestep your regular hygiene process, such as washing your hands.
- Always have a backup plan. Carry a spare set of lenses or a pair of eyeglasses. It’s also a good idea to keep contact solution or eye drops in your purse, backpack, or office.
- If you’ve fallen asleep on an overnight trip and realize you didn’t bring your contact lenses or cleaning supplies, find a pharmacy as soon as possible so that you can remove and clean your lenses. At the very least, put in eye drops so your lens can rehydrate and reduce the pressure on your cornea, and it is imperative to remove your lens as soon as possible.
- Never put your contact lenses in your mouth to moisten or clean them. Saliva is not sterile and will increase the risk of an eye infection.
- Before wearing your contact lenses again, ensure they are thoroughly cleaned and inspect them for small tears or other imperfections. If you notice any irregularities, throw them away. And start with a fresh pair. It’s always a good idea to go at least one day without contact lenses if you’ve slept in them; this will give your eyes a chance to recover.
- If you experience any symptoms of an eye infection or discomfort, seek care from your eye care professional.
Always practice safe habits and check with your eye care professional whenever you doubt.
NewsMakers
Heart disease risk may start in the womb, study finds
Young adults whose mothers had high blood pressure during pregnancy — either pregnancy-associated hypertension, pre-eclampsia or eclampsia — had more signs of early arterial injury, higher blood pressure, higher body mass index and higher blood sugar than peers.
A child’s future heart health may be partially shaped before they are born, reports a new Northwestern Medicine study that found pregnancy complications are linked to poorer cardiovascular health in offspring more than 20 years later.
The study found that young adults whose mothers had high blood pressure during pregnancy — either pregnancy-associated hypertension, pre-eclampsia or eclampsia — had more signs of early arterial injury, higher blood pressure, higher body mass index and higher blood sugar than peers.
The authors said the study adds to growing evidence that cardiovascular risk may be transmitted across generations through a combination of biological, environmental and behavioral factors.
“That means we must make sure people maintain good health from childhood into young adulthood, so that if or when someone becomes a parent, they pass on the best opportunity for good health to their children,” said study senior author Dr. Nilay Shah, assistant professor of medicine in the division of cardiology at Northwestern University Feinberg School of Medicine.
How the study was conducted
Shah and colleagues evaluated nearly 1,350 mother-child pairs from the Future of Families and Child Well-Being Study, which enrolled mothers and children at birth between 1998 and 2000 across 20 U.S. cities. The children were then followed into adulthood.
Using delivery hospitalization records, the Northwestern scientists first identified whether mothers experienced pregnancy complications, including high blood pressure during pregnancy, gestational diabetes (high blood sugar during pregnancy) or preterm birth (before 37 weeks of pregnancy).
The three pregnancy complications are on the rise, and affect almost one in four pregnancies in the U.S.
The research team then analyzed cardiovascular health of offspring at age 22, using blood pressure measurements, blood testing, body mass index assessments and carotid artery ultrasounds to look for signs of artery injury.
Finally, the scientists compared participants with and without exposure to each pregnancy complication and adjusted for factors like income, education, difference in birth weight and smoking during pregnancy.
Key findings
At around age 22, participants whose mothers had high blood pressure during pregnancy had:
- Higher body mass index (+2.8 BMI points)
- Higher diastolic blood pressure (+2.3 mm Hg)
- Higher blood sugar levels (+0.2% HbA1c)
- Thicker artery walls (~0.02 mm)
While the difference in artery wall thickness may seem small, the study authors said it corresponds to roughly three to five years of additional vascular aging. That means arteries looked older and less healthy than expected, which raises the risk of future heart disease.
Other pregnancy complications also showed some long-term effect:
- Exposure to gestational diabetes was linked to worse blood pressure and some evidence of artery thickening
- Being born preterm was associated with higher blood sugar levels
‘Most heart disease is preventable’
With pregnancy complications on the rise in the U.S., Shah said the study provides compelling evidence that improving health before and during pregnancy could help reduce heart disease risk in the next generation.
“There is evidence that both parents’ health at the time of conception and during pregnancy influences a child’s health,” he said. “So, promoting health from an early age, like exercising regularly, eating healthfully, never smoking and getting enough sleep, is not just meant for an individual, but doing so may help future generations be healthier, too.”
Shah also emphasizes that risk is not destiny.
“The good news is that most heart disease is preventable,” he said. “If you experienced high blood pressure or high blood sugar during pregnancy, or your child was born early, it does not absolutely mean that your child will have worse health as adults. But I would encourage you to pay attention now to your child’s health behaviors.
“What children learn in childhood sets the stage for their health across their lives. If you are wondering whether your children’s behaviors are healthy, or are considering making a change, please speak with your child’s pediatrician for advice and guidance.”
Other Northwestern co-authors include Emily Lam, Abigail Gauen, Dr. Sadiya Khan, Alexa Freedman and Norrina Allen.
NewsMakers
Viagra could hold key to halting Peyronie’s disease
Combining two widely prescribed drug classes could provide the first effective treatment for early-stage Peyronie’s disease.
Combining two widely prescribed drug classes could provide the first effective treatment for early-stage Peyronie’s disease, according to a study published in The Journal of Sexual Medicine.
Peyronie’s disease (PD) is caused by the development of fibrotic scar tissue within the penis, leading to pain, curvature, sexual dysfunction and, in many cases, significant psychological distress. It affects an estimated 10 per cent of men during their lifetime, but despite its prevalence, treatment options are limited, particularly in the early phase of the condition.
The study, carried out by Anglia Ruskin University (ARU) and University College London Hospital (UCLH), found that combining phosphodiesterase type 5 (PDE5) inhibitors such as sildenafil (Viagra) and tadalafil (Cialis) with selective oestrogen receptor modulators (SERMs), including tamoxifen, may slow or even stop disease progression when given early.
The clinical study, carried out by Professor David Ralph of UCLH, evaluated outcomes in 133 men diagnosed with acute Peyronie’s disease who were treated with the drug combination for three months. Their results were compared with a smaller group of patients receiving standard care, which included giving vitamin E or no treatment at all. Standard care did not include surgery.
The study found 43 per cent of patients on the combination experienced an improvement in penile curvature, almost three times higher than in the standard‑care group (15 per cent).
At the start of treatment, 65 per cent of patients in the combination group reported pain during erections. After three months, that figure had fallen to just 1.5 per cent. By comparison, pain prevalence in the standard‑care group fell from 50 per cent to 27 per cent.
The clinical findings build on earlier laboratory work led by Professor Selim Cellek at ARU’s Fibrosis Research Group. Over the course of several years, Professor Cellek’s team screened 1,953 FDA‑approved drugs to identify compounds capable of blocking the transformation of fibroblasts into myofibroblasts, the key cells responsible for fibrosis. PDE5 inhibitors and SERMs emerged as particularly effective, and when used together demonstrated an effect greater than either drug alone.
Currently, there are no approved oral therapies proven to prevent early disease progression, forcing patients in the acute phase to wait until the condition stabilises before they can be offered treatments including injections or surgery.
Professor Cellek said: “Positive findings from this pilot clinical study validate our drug‑screening approach in the lab. It shows how repurposing well‑known medicines can accelerate progress in areas of unmet clinical need.
“Because both PDE5 inhibitors and SERMs are already widely used in clinical practice and have established safety profiles, the approach could be readily adoptable if confirmed in larger studies.
“These results suggest that early intervention targeting fibrosis could change how we treat Peyronie’s disease. Repurposing existing drugs may allow us to move from managing symptoms to modifying the disease itself.”
Professor David Ralph, Professor of Urology at UCLH, said: “This paper confirms the basic science research with regards to halting the progression of Peyronie’s disease. In previous papers we have noted that tamoxifen and PDE5 inhibitors inhibit the transformation of fibroblasts into myofibroblasts and therefore contraction of the plaque.
“This has now been put into clinical practice where this paper shows that when tamoxifen and a PDE5 inhibitor are combined, there is statistically less progression of the disease and improvement in curvature compared to the control arm. This is where from bench to clinical practice prevails and hopefully now a prospective clinical trial can be initiated.”
NewsMakers
Healthier brains may be more resilient to early Alzheimer’s disease
Maintaining good overall brain health may help reduce the impact of Alzheimer’s‑related changes on cognitive function.
A healthy brain may help protect thinking and memory skills from the early effects of Alzheimer’s disease, a new study has found.
Dementia is currently the leading cause of death in Australia and Alzheimer’s disease is its most common form — accounting for more than 70% of cases.
Alzheimer’s is a progressive brain disease in which cognitive abilities gradually decline, leading to impaired memory and thinking skills.
However, some people maintain high levels of cognitive function even though their brains show early signs of the disease. Specifically, some older adults have Alzheimer’s‑related brain pathology, but no noticeable cognitive problems.
The study, Cognitive and Brain Reserve as Modifiers of Early Alzheimer Disease–Related Cognitive Vulnerability, was a collaboration between Murdoch University and AdventHealth, and investigated why some people remain cognitively healthy despite early Alzheimer’s‑related brain changes.
“Our study looked at why some brains were more resilient than others, and whether factors such as peoples’ education, socioeconomic status and health of their brain made a difference,” said lead author Dr Kelsey Sewell, from Murdoch University’s School of Allied Health.
“Understanding these protective factors could help us develop earlier and more targeted strategies to minimise the effects of the disease on memory and thinking skills,” she said.
The research team analysed data from more than 600 older adults in the United States aged 65 to 80, who were living independently and had no signs of dementia or memory impairment.
They used blood tests and MRI scans to assess early Alzheimer’s‑related changes and overall brain health, examined life and social factors such as years of education, income, savings and financial security, and conducted cognitive tests measuring memory, attention, processing speed, working memory and executive function.
“Our main finding was that maintaining good overall brain health may help reduce the impact of Alzheimer’s‑related changes on cognitive function,” Dr Sewell said.
“We also observed early evidence that people with a higher socioeconomic status may be less affected by Alzheimer’s-related changes when it comes to memory, although more research is needed to confirm this relationship.”
Dr Sewell said the main takeaway for the public was to do everything you can to maintain a healthy brain.
“Things like exercise, maintaining a healthy diet, sleeping well, and finding new cognitive challenges can help to maintain a healthy brain. It is never too late, or too early to start,” she said .
“These results underscore the need for coordinated action across research, policy, and industry to design environments that support healthier choices and promote brain health at a population level.”
The data collection for this study was led by researchers at AdventHealth in Orlando, Florida.
The paper, Cognitive and Brain Reserve as Modifiers of Early Alzheimer Disease–Related Cognitive Vulnerability, was published in the journal Neurology.
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