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Mental well-being and physical activity can form a positive cycle

The study found no connection between experiencing negative affectivity and physical activity when depressive feelings were considered. The experience of depressive feelings can include other symptoms besides negative affectivity, such as insomnia and loss of appetite. Therefore, depressive feelings may be a more comprehensive risk factor for low physical activity than negative affectivity alone.

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In a study conducted at the Gerontology Research Center and the Faculty of Sport and Health Sciences at the University of Jyväskylä, Finland, it was found that most men and women aged 60 to 88 either maintained or even increased their level of physical activity during the restrictions imposed by the COVID-19 pandemic. Participants who experienced more positive affectivity had higher physical activity levels and were more likely to increase their activity during the restrictions. 

“It was interesting to observe that the link between positive affectivity and physical activity was more consistent in individuals around the age of 60 than in those over 70,” says postdoctoral researcher Tiina Savikangas. 

“In Finland, no curfew was declared but the older participants faced stricter restrictions compared to working-age individuals, which may have reduced the role of positive mental well-being on physical activity.” 

Previous research evidence has shown that physical activity contributes to mental well-being. However, recent findings suggest that mental well-being can also help maintain a physically active lifestyle. Mental well-being and physical activity may thus form a positive cycle. 

“Mental well-being is an important resource for physical activity.” 

“Those who have such resources are more likely to stay active, even during exceptional circumstances”, Savikangas notes.  

The study also found that experiencing depressive feelings during the COVID-19 pandemic was associated with lower levels of physical activity and a higher likelihood of reducing activity. The link between depressive feelings and lower physical activity was particularly pronounced among participants over 70. The findings suggest that different aspects of mental well-being may have varying significance for physical activity at different ages. 

“Supporting mental well-being is crucial for promoting a physically active lifestyle, even in societal emergencies,” Savikangas explains. 

“However, the focus should not only be on preventing depressive feelings but also on strengthening the positive side of mental well-being.”  

The study found no connection between experiencing negative affectivity and physical activity when depressive feelings were considered. The experience of depressive feelings can include other symptoms besides negative affectivity, such as insomnia and loss of appetite. Therefore, depressive feelings may be a more comprehensive risk factor for low physical activity than negative affectivity alone. 

The research publication is based on the Jyväskylä Longitudinal Study of Personality and Social Development (JYLS), especially its latest data collection phase Developmental Psychological Perspectives on Transitions at Age 60: Individuals Navigating Across the Lifespan (TRAILS) and Promoting Safe Walking Among Older Adults (PASSWORD), both conducted at the Faculty of Sport and Health Sciences and the Gerontology Research Center, University of Jyväskylä, Finland. A total of 162 men and women aged 60 to 61 from TRAILS participated in this study by responding to a survey on physical activity during the COVID-19 pandemic between April 2020 and July 2021. From PASSWORD, 272 men and women aged 72 to 88 participated by responding to a postal survey conducted between April and June 2020. The amount of physical activity during the COVID-19 pandemic and changes in it were assessed using a questionnaire specifically developed for this purpose by the Faculty of Sport and Health Sciences. Positive and negative affectivity, as well as depressive feelings, were measured using self-reports. Additionally, factors such as participants’ gender, marital status, education level, employment status, perceived health, usual physical activity and, in the older cohort, age, were taken into account. The JYLS study is led by research director Katja Kokko, and the PASSWORD study by Professor of Sport Gerontology Sarianna Sipilä. Both studies were funded by the Academy of Finland. 

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Wellness

Men’s health expert issues warning to fans copying Mark Wahlberg’s early starts

Getting up at 3 a.m. might look like a head start in a social media morning routine. But for men tempted to copy it, there is an important question to answer before setting the alarm: what time will you actually be asleep?

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A men’s health expert explains why copying an early alarm without changing your bedtime could leave you tired, unfocused and less productive

Getting up at 3 a.m. might look like a head start in a social media morning routine. But for men tempted to copy it, there is an important question to answer before setting the alarm: what time will you actually be asleep?

Anneliese Cadena, a board-certified nurse practitioner and clinical consultant at Feel30, is encouraging men to protect their sleep when adopting an earlier routine. Moving the alarm forward without bringing bedtime forward can reduce the rest needed to function well during the day.

“If you normally wake up at 7 a.m., suddenly setting your alarm for 3 a.m. while keeping the same bedtime cuts four hours from your opportunity to sleep. That can leave you feeling worse during the day, even if you manage to get out of bed.”

The consequences can undermine the very reason for getting up early. According to the National Heart, Lung, and Blood Institute, insufficient sleep can affect concentration, decision-making and reaction times, leaving people taking longer to finish tasks and making more mistakes.

For someone who needs eight hours of sleep, a 3 a.m. alarm means being asleep by 7 p.m. the previous evening. That also requires time beforehand to wind down and fall asleep.

Start with a smaller change

For men who want an earlier start, a more manageable approach is to adjust the evening routine gradually.

Cleveland Clinic recommends moving bedtime earlier by 15 or 20 minutes for a few days, then making another small adjustment. Its guidance advises seven to nine hours of sleep each night.

Someone who usually wakes at 7 a.m. could start by working toward 6:45 a.m., alongside an earlier bedtime. Further changes should leave enough time for sleep. Moving the alarm forward by a full hour every day can quickly eat into rest if bedtime does not keep pace.

If falling asleep earlier proves difficult, or daytime sleepiness increases, pause further changes and reconsider whether the target wake-up time fits your needs.

Anneliese adds: 

“Choose a wake-up time that fits your responsibilities and still gives you enough sleep. Getting up at 6 a.m. and feeling rested may serve you much better than forcing a 3 a.m. start that leaves you struggling through the afternoon.”

An earlier morning starts the evening before

Changing the alarm may also mean reconsidering an afternoon coffee or a late evening spent scrolling.

The NHLBI recommends keeping a consistent sleep schedule and using the hour before bed for quiet time, while avoiding bright artificial light. It also notes that caffeine’s effects can last up to eight hours, which matters when bedtime moves earlier.

Morning daylight can help support an earlier sleep schedule. Spending time outside once it is light is one practical step, although people differ in when they naturally feel sleepy and alert.

What does sleep loss mean for testosterone?

Testosterone is one area researchers have investigated, although the findings do not justify claiming that a 3 a.m. alarm causes low testosterone.

A small University of Chicago study published in 2011, involving 10 healthy young men, found daytime testosterone levels were approximately 10% to 15% lower after about a week of sleep restricted to five hours a night, compared with a longer sleep condition.

However, two randomized studies published together in 2019 did not find an adverse effect on testosterone under the sleep-restriction conditions they tested. The studies used different schedules and measurements, and neither paper tested the social media trend itself.

The evidence supports taking sleep seriously without assuming that tiredness automatically signals a hormone problem.

Wyoming, Alaska and Montana lead searches for testosterone therapy

Separately, Feel30’s analysis of 312 testosterone replacement therapy (TRT) search terms recorded a combined estimated U.S. search volume of 3.37 million between September 2025 and August 2026.

Wyoming had the highest estimated search rate relative to population, followed by Alaska and Montana.

RankStateEstimated annual searches per 100,000 residents
1Wyoming3,093.0
2Alaska2,575.7
3Montana2,336.9
4North Dakota2,298.1
5Hawaii2,174.0
6South Dakota2,091.8
7Delaware2,056.7
8New Hampshire2,041.2
9Vermont2,029.0
10Rhode Island2,011.6

Rates use total state populations. Figures estimate searches, not individual searchers, patients or diagnoses.

Wyoming’s rate was almost three times California’s 1,045.7 searches per 100,000 residents. California recorded the largest total estimated volume, at 411,520, but ranked 41st once population was taken into account.

The rankings show geographic differences in search activity. They do not identify the states with the lowest testosterone, and the analysis did not measure sleep habits or establish any connection with early waking.

When tiredness needs checking

Persistent tiredness deserves a medical assessment, especially alongside loud snoring, gasping during sleep or breathing that stops and starts. These can be signs of sleep apnea.

Tiredness alone cannot diagnose low testosterone. The Endocrine Society recommends diagnosis only when compatible symptoms and signs are accompanied by consistently low testosterone levels, confirmed through repeat morning fasting blood tests. Treatment decisions require an appropriate clinical assessment.

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Wellness

Structured exercise linked to longer cancer survival and time free of disease

Those who exercised as part of their care were 23% less likely to die and 17% less likely to have a recurrence before death than those who didn’t exercise. Separate analyses showed that they were also 18% less likely to die from any cause, and 26% less likely to die from their cancer.

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Structured exercise may help people with cancer live longer and have more time free of disease, finds a synthesis of the available evidence, published in the British Journal of Sports Medicine.

The survival and recurrence risk benefits were strongest in early stage disease, in those who did aerobic exercise or aerobic exercise plus strength training, and in those who managed to keep up their exercise routines, the findings indicate.

Their analysis prompts the researchers to conclude that incorporating the therapeutic potential of exercise into cancer care merits consideration.

Cancer comes back in between 20%–40% of patients, even after standard curative surgery and chemotherapy, point out the researchers.

While structured exercise is widely recommended to ease fatigue and improve physical functioning and quality of life, its potential to prolong survival and stave off disease recurrence remains a subject of debate, they add.

In a bid to strengthen the evidence base, the researchers scoured research databases for randomised controlled clinical trials published up to the end of 2025 and reporting on survival and disease recurrence in adults with confirmed cancer who were given structured exercise programmes as part of their care.

From an initial haul of 123 studies, 21 clinical trials from North America, Europe, Australia, and Asia, involving a total of 8449 participants (88% women), met the eligibility criteria.

The average age of participants was 54 (range 47–76), and the average monitoring period was 64 months (range 2–99 months). The most common type of cancer studied was that of the breast followed by those of the bowel and pancreas.

Pooled data analysis of the results showed that structured exercise was associated with significant improvements in overall survival.

Those who exercised as part of their care were 23% less likely to die and 17% less likely to have a recurrence before death than those who didn’t exercise. Separate analyses showed that they were also 18% less likely to die from any cause, and 26% less likely to die from their cancer.

But there was no clear evidence that structured exercise prolonged the time before patients’ cancer worsened or increased the likelihood that no invasive cancer remained after standard treatment.

An exploratory analysis showed that the associations were stronger among participants who completed at least 70% of their exercise programme.

Overall survival estimates favoured aerobic exercise alone and programmes combining aerobic exercise and strength training. No clear association was found for strength training alone, but this finding was based only on one trial, involving 129 participants, note the researchers

“Aerobic exercise drives systemic cardiovascular conditioning, immune cell mobilisation, and normalisation of tumour perfusion, mechanisms directly relevant to systemic tumour control,” explain the researchers.

There are plausible biological explanations for the beneficial effects of exercise on cancer survival and risk of recurrence, they suggest.

Exercise may boost the body’s immune system response to cancer and improve blood flow within tumours, potentially helping treatment to work better. It may also lower circulating levels of sex specific hormones and increase glucose uptake by muscles, leaving less available to fuel cancer cells, they highlight. And it may help cells repair DNA damage, potentially limiting changes that can make tumours more aggressive, they add.

The researchers acknowledge various limitations to their findings, including the migration of participants in comparison groups to healthier behaviours; considerable variations in the type, duration, and intensity of the included exercise interventions; and a predominance of evidence from breast cancer trials, with relatively little evidence on advanced stage disease.

Nevertheless, they conclude: “Our meta-analysis provides direct, quantified evidence suggesting that the benefits of structured exercise may extend beyond supportive care to outcomes traditionally associated with therapeutic interventions, while underscoring that observed effects are context dependent and sensitive to trial design, conduct, and feasibility.”

They add: “On the strength of this evidence, clinicians can reasonably recommend structured exercise as part of oncological care, while recognising that important questions remain and that ongoing trials will continue to refine its optimal application.”

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Workout or nap? Either can help your sleepless brain, study finds

People who either completed 20 minutes of moderate-to-vigorous exercise or took a 90-minute nap performed about 22 per cent better on memory tests after 30 hours without sleep than those who did neither.

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A short workout or a nap can help protect memory after a sleepless night, a McGill University-led study has found.

Researchers found people who either completed 20 minutes of moderate-to-vigorous exercise or took a 90-minute nap performed about 22 per cent better on memory tests after 30 hours without sleep than those who did neither. The findings, published in Proceedings of the National Academy of Sciences (PNAS), point to practical ways to counter the effects of sleep deprivation.

“Sleep loss affects nearly every aspect of how we think and function, but many people can’t simply stop what they’re doing and get more sleep,” said senior author Marc Roig, Professor in McGill’s School of Physical and Occupational Therapy. “Our findings show that even a brief bout of exercise may help preserve one of our most important cognitive abilities.”

The study involved 54 healthy young adults who stayed awake for 30 consecutive hours under lab supervision. Participants were then assigned to one of three groups: a 20-minute cycling session, a 90-minute nap or a control condition. Three days later, researchers tested their memory for images they had viewed immediately after the intervention. Those who exercised or napped remembered significantly more images than participants who did neither.

Same result, different pathways

While the memory benefits were nearly identical, brain recordings revealed that exercise and napping helped in different ways.

Napping appeared to help the brain recharge, making it easier to take in and remember new information. Exercise, by contrast, helped the brain use its remaining resources more efficiently, without making participants feel more tired.

The findings could eventually inform fatigue-management strategies in workplaces where sleep loss is common and mistakes can have serious consequences, such as health care, transportation and emergency response.

“A nap isn’t always possible in the middle of a shift,” said first author Madhura Lotlikar, a doctoral candidate in McGill’s Department of Neurology and Neurosurgery. “Exercise is accessible, inexpensive and easy to implement. That makes it a promising tool to help people stay cognitively sharp when sleep is limited.”

The researchers emphasize that exercise cannot replace sleep, but it may help people function better when getting enough rest isn’t possible.

About the study

“Protecting episodic memory after sleep loss: Similar benefits of exercise and naps via distinct neural contributions” by Madhura Lotlikar and Marc Roig et al., was published in Proceedings of the National Academy of Sciences of the United States of America.

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