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Synchronizing your internal clocks may help mitigate jet lag, effects of aging

Having a larger meal in the early morning of the new time zone can help overcome jet lag. Constantly shifting meal schedules or having a meal at night is discouraged, as it can lead to misalignment between internal clocks.

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Traveling to faraway places is a great way to seek out new experiences, but jet lag can be an unpleasant side effect. Adjusting to a new time zone is often accompanied by fatigue, difficulty sleeping, and a host of other problems that can turn an otherwise exciting adventure into a miserable trip.

Jet lag is caused by a difference between the circadian system — the body’s internal clock — and the surrounding environment. Around the turn of the century, scientists began to recognize that the body has multiple internal clocks, calibrated in different ways, and that jet lag-like symptoms can result when these clocks drift out of sync with each other. This can happen in several ways and grows more prevalent with age.

In Chaos, from AIP Publishing, a team of scientists from Northwestern University and the Santa Fe Institute developed a theoretical model to study the interactions between multiple internal clocks under the effects of aging and disruptions like jet lag.

Modern research has shown that circadian clocks are present in almost every cell and tissue in the body. Each relies on its own set of cues to calibrate; the brain’s clock depends on sunlight, for instance, while the peripheral organs calibrate at mealtime.

“Conflicting signals, such as warm weather during a short photoperiod or nighttime eating — eating when your brain is about to rest — can confuse internal clocks and cause desynchrony,” said author Yitong Huang.

At this point, little is known about how the body’s various internal clocks affect each other. The added complexity of accounting for multiple clocks means researchers tend to use simplified models.

“Most studies primarily focus on one particular time cue or a single clock,” said Huang. “Important gaps remain in our understanding of the synchronization of multiple clocks under conflicting time cues.”

Huang and her colleagues took a different approach, building a mathematical framework that accounts for this complex interplay between systems. Their model features two populations of coupled oscillators that mimic the natural rhythms of circadian cycles. Each oscillator influences the others while simultaneously adjusting based on unique external cues.

Using this model, the team was able to explore how such a coupled system could be disrupted and what makes the effect worse. They found that common symptoms of aging, such as weaker signals between circadian clocks and a lower sensitivity to light, result in a system that is more vulnerable to disruptions and slower to recover.

They also landed on a new method to speed up recovery from jet lag and similar disruptions. According to their results, the way to better sleep is through the stomach.

“Having a larger meal in the early morning of the new time zone can help overcome jet lag,” says Huang. “Constantly shifting meal schedules or having a meal at night is discouraged, as it can lead to misalignment between internal clocks.”

The article, “A minimal model of peripheral clocks reveals differential circadian re-entrainment in aging,” is authored by Yitong Huang, Yuanzhao Zhang, and Rosemary Braun. It appeared in Chaos.

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Destinations

Enjoying the grilling at Mandaue City’s Matias BBQ

#Mandaue City’s #MatiasBBQ is worth checking as your #LGBT alternative to dining in the open in #Cebu.

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Seriously considering Larsian to try grilled goods in Cebu City, a friend recommended for us to try, instead, Matias BBQ. “It’s cleaner,” she said, adding: “And yummier, of course.”

So we checked… and how was the visit to Matias BBQ for us?

@outragemag #Mandaue City’s #MatiasBBQ is worth checking as your #LGBT alternative to dining in the open in #Cebu ♬ original sound – Outrage Magazine

Una, the place is NOT in Cebu City. It’s in nearby Mandaue City. We didn’t check where the BBQ place is, exactly; we just took a Grab and pinned the address. We just noted that the travel took a while, and yes, the fare wasn’t cheap (LOL).

Ikalawa, this is an open-air venue, similar to Larsian, though the difference is, here, there’s just one vendor (Matias BBQ). Maarte people beware: this isn’t for you.

Ikatlo, the servers were friendly… a pleasant surprise considering the number of people they had to serve. They knew what to recommend, and quickly dealt with some concerns (e.g. replace what was deemed stale rice).

Ika-apat, how was the food naman?

  • The chicken – including the ₱85 pecho and ₱95 paa – were well-seasoned and well-cooked, remaining moist and not dry. Lasa-wise, they were smoky and sweetish.
  • The ₱16 chorizos were actually good, properly cooked so that we were still able to taste the meat and accompanying sahog of garlic and the likes. This made us realize that when deciding to cook longganisa from Cebu, consider grilling instead of frying in oil. It just tastes better that way.
  • The ₱165 balbacua (beef rind and oxtail soup) served to us was already cold, so was already greasy. The collagen-rich cuts were soft, and there were okay-tasting veggies, but the broth was already slimy from being oily.
  • The ₱12 pusô was inconsistent; some were already stale (perhaps old stocks), and the others fresh. It’s hard to ascertain which is which since you’d be served with a lot. Order freshly-cooked rice if apprehensive… though this takes away from the overall experience of eating in a place like this.

Here’s the thing: our total bill was cheaper than the fare we paid to Grab to go there.

And so, for us, if this is accessible to you, consider this an alternative to, say, the likes of Larsian. That the food is good has to be emphasized, done in an outdoor setting that’d remind you of eating in the probinsiya.

But off we go again, in search of more LGBTQIA+ lagangan venues…

Open from 11.30AM to 8.00PM, Matias BBQ is located along A.S. Fortuna St., Banilad, Mandaue City.

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Destinations

Eating out in Cebu in one place via Pusô Village

Checking out #Cebu’s all-in-one dining location, the Pusô Village that may simplify eating out but seems to forget our desire to see diverse #foodie hubs.

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In the past, if you wanted to grab some of the food associated with Cebu, you headed to – among others – Larsian, this place not too far from Fuente Osmeña Circle. It wasn’t necessarily popular with the locals who saw (and still see) it as unhygienic, but it’s this easy-to-access BBQ place that’s open 24/7.

Starting 2025, however, a new place was opened to serve as the one-stop culinary and cultural hub of Cebu City: the Pusô Village.

@outragemag Checking out #Cebu's all-in-one dining location, the Pusô Village (#pusovillage) that may simplify eating out but seems to forget our desire to see diverse #foodie ♬ original sound – Outrage Magazine

Una, developed by Cebu2World/Megawide as part of the Carbon Market modernization, this place’s name drew inspiration from the pusô rice cake that’s served when you have meals in Cebu. There are, therefore, design elements that’d remind you of the pusô – e.g. those octahedral shapes on the entrance. Inside, there are attempts to beautify by borrowing elements from Bahay na bato Philippine architectural style; most are fake, though, such as those painted-on verandahs you’d see when you look up.

Ikalawa, there are over 100 food stalls and retail outlets here… though more of the former than the latter. They’ve been “properly” structured, so that the lechon vendors are on one side, seafood sellers on another side, and so on.

Ikatlo, we tried some of the offerings to ascertain how good they are.

The unlimited lechon is popular, providing an opportunity particularly for non-locals to cheaply enjoy this Cebuano treat. Taste-wise, the lechons vary little, some saltier than the others. The “approach” in serving is similar, though. You get an okay portion when first served, and the portion gets smaller the more you return. Noticeably, by the third refill, the vendors become grumpier when serving you, some even ignoring you, or stuffing fatty parts on your plate. Business greed in action.

Though cooked the same way (i.e. buttered), the seafood platters are inconsistent. You could get some shrimps or crabs now and then, though most times, you’d just get mussels.

Then there’s the tuslob-buwa, pig’s brain cooked under maximum heat to then become dip for pusô. We’d say this is acquired taste… but there’s not much to taste. So this is a costly to-try food.

Only open until 10.00PM, Pusô Village offers those in Cebu a venue to try as many of the local goods as possible. For that, alone, this is a must-check. You are sure to find a few stuffs you’d like.

But the city still has a lot of venues offering local culinary and cultural goods, and they deserve to be also checked. And so off we go for more LGBTQIA+ rampa

Pusô Village is located at M.L Quezon Blvd., Sto. Nino, Cebu City.

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Destinations

Going Chinese in Pulilan, Bulacan

Craving for #chinesefood in #Bulacan? We tried the offerings of Lee Foo Panciteria #Pulilan, and we’re on the fence here (yes if no choice, no if you can go elsewhere).

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We happened to be in Pulilan in Bulacan, and I had pancit craving. As if on cue, we passed by Lee Foo Panciteria Pulilan, which – after we Google-checked – is supposedly one of the more frequently-visited Chinese restos in these parts of the province, so… of course we checked.

@outragemag Craving for #chinesefood in #Bulacan? We tried the offerings of Lee Foo Panciteria #Pulilan ♬ original sound – Outrage Magazine

Una, this place is really, REALLY easy to find. Located along the Pulilan Regional Road in Barangay Cut-cot in Pulilan, this is right in the middle of the municipality.

Ikalawa, the resto is actually divided into three parts: one side is for those with reservations, another part is for walk-in diners, and another part is for events. If/when the resto isn’t full, only the main part (middle one) is kept open.

No, this isn’t some fancy resto. More like an airconditioned karinderya, complete with wooden tables and plastic chairs. Look-wise, it wasn’t dirty naman when we were there, so that’s a plus.

Ikatlo, the workers were friendly naman… and they moved fast – e.g. while waiting for our orders, we were given must-check peanuts, and since we finished what we got fast, our waitress was more than happy to accommodate us.

Ika-apat, now… how was the food?

The house specialty, the Lee Foo Chicken (₱265 for half, ₱495 for whole), looked like fried chicken with ketchup. Okay… the breading was okay since it didn’t overpower the meat. The chicken, too, was properly cooked, and it wasn’t dry. But it was tasteless overall; so the ketchup taste is what stays with you.

The Pancit Canton Bihon (₱255) had thin pancit noodles, almost as thin as the bihon. It didn’t have lots of sahog; instead, you’d notice the extenders (like kikiam, and so on). I like good pancit, I swear… but this isn’t one of them, sorry.

The weirdly-wrapped Hakaw (₱155) was small, so it was bitin.

And then there’s the Siomai Steam (₱155), which was, in a word, weird. The size was good, similar to those ₱10 siomais. But the way this was prepared was weird for us – e.g. like the meat was overwatered, and having a hard time staying solid, so that it was smudgy, and disintegrated in the mouth even without chewing. I suppose that, at least, it wasn’t disgusting taste-wise.

Lee Foo Panciteria Pulilan is, we believe, popular. Like President in Chinatown, or a branch of David’s in some mall. To each his or her own nga naman. But for us, we’re off to look for other Chinese restos na muna as we head out in search of more lafangan venues.

Lee Foo Panciteria Pulilan is located at 159 Barangay Cut-cot, Pulilan, 3005 Bulacan Province. For more information, contact 0925 800 0168, or email leefoopanciteria@yahoo.com.

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