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Dengue vaccine now available at select Watsons stores

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Dengvaxia, a vaccine against dengue, is now available over-the-counter nationwide at select stores of Watsons, the first retailer to offer the vaccine in the Philippines.

Watsons Dengue Vaccine KV 2

“We decided to offer dengue vaccination in our 108 selected stores nationwide as we recognize the importance of having vaccination accessible to Filipinos to protect them against dengue infection and make them healthier. It is our latest addition that we offer in our stores, aside from cervical cancer, flu and pneumonia vaccinations,” says Danilo Chiong, Watsons Trading Health Director.

Produced by pharmaceutical firm Sanofi Pasteur, Dengvaxia took over 20 years of extensive research and tests to develop. Studies on the vaccine were conducted on 41,000 people and were carried out in 15 countries including the Philippines. With test results fully reviewed by a committee of independent experts, the vaccine has been recommended by the World Health Organization (WHO).

In a WHO position paper published in July 29, 2016, it says that to prevent dengue infection, dengue vaccine should be a part of a comprehensive dengue control strategy, which include well-executed and sustained vector controls, evidence-based best practices for clinical care and strong dengue surveillance.

The vaccine has also been endorsed by the Philippine Society for Microbiology and infectious Diseases (PSMID) and Philippine College of Physicians (PCP). In February 2017, the vaccine got the approval to be administered in 14 countries, including the Philippines, where dengue is endemic.

In the Philippines, there were 211,106 reported dengue cases in 2016. The most number of cases was reported in Regions VI, VII, III, IV-A, and XII. All age groups were affected by dengue.

Age bracket and dosage

Since there is no specific treatment for dengue, Dr. Rontgene Solante, Past President at PSMID, said the dengue vaccine can protect individuals against the illness. It can be administered to individuals 9 to 45 years old living in endemic areas for prevention of dengue illness caused by dengue virus serotypes 1, 2, 3 and 4. It is to be taken in three doses of 0.5ml at six-month intervals to increase antibodies response, thereby protecting them from all four strains of the virus. The vaccine, when correctly administered in three doses, stays effective in four to five years.

The vaccine costs P4,000 per dose or P12,000 for all three doses, which is reasonable considering the high incidence of dengue and high cost of treatment in the Philippines.

“The vaccine is not just for kids but adults should also be vaccinated as this is safe and can modify infection. Don’t look at the price but in the long-term benefits it provides,” said Solante.

Solante, however, relayed the vaccine is not effective for children below nine years old. A study made on the vaccine and these children showed that the efficacy of the vaccine was below 50%. Likewise, the vaccine cannot be administered to persons over 45 years old as there was no study made yet about its effectiveness for these individuals.

Apart from these, other persons who have the following cannot take the vaccine: history of severe allergic reaction; congenital or acquired immune deficiency diseases; symptomatic HIV infection; and pregnant or breastfeeding women.

Solante, however, said that those were infected by dengue in the past can still avail of the vaccine.

Solante advised individuals to administer the vaccine correctly. “If a person who has taken the first dose fails to take the second dose on the scheduled (sixth) month, and instead take it, let’s say, on the eighth month, the vaccine is still effective. But, if he misses taking it for a couple of years, the vaccine became ineffective and has to start taking it all over again.”

The vaccine is injected in arms via the subcutaneous route over the deltoid region. How is it effective? In his presentation, Dr. Solante said the vaccine can result to 80.8% reduction in hospitalized dengue; 93.2% drop in severe dengue; and 65.6% decline in symptomatic dengue, which means that if a person is infected, symptoms are reduced.

The vaccine does not contain adjuvants or preservatives so the adverse effect or reaction is lower, according to Solante. Adverse reactions include headache, malaise, myalgia, pain, injection site reaction, and other mild to moderate reactions.

A study conducted by the University of the Philippines showed that the vaccine is expected to reduce dengue cases in the country by over 24% in a span of five years.

Meanwhile, Chiong said that they will have a doctor in over 100 selected Watsons stores to administer the vaccine during vaccination dates. The first scheduled dengue vaccination will be on April 30, 2017 (1st dose); October 29, 2017 (2nd dose) and April 29, 2018 (3rd dose). The second schedule vaccination will be on May 14, 2018 (1st dose); November 12, 2018 (2nd dose); and May 13, 2018 (3rd dose).

REYNALDO “Rey” R. VICENTE’s career experience involves mostly research in publishing companies. He previously held the position of Research and Events Director of Media G8way Corp., publisher of Computerworld Philippines (CWP), PC World Philippines, and IT Resource. He also handled events organized for CWP. Prior to this, he was a Research Head of a business publication. Now as co-publisher of Zest Magazine, Rey also serves as Managing Editor. Rey finished his bachelor’s degree majoring in Economics at the University of Santo Tomas.

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5 Tips to upgrade your sleep

Sleep contributes to better brain function, memory, concentration and lower stress. According to the National Institutes of Health, most adults need 7-9 hours of sleep every night to achieve maximum health benefits.

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Good sleep isn’t just about waking up feeling rested and ready for the day. Quality sleep, and plenty of it, is important for your overall health. While you sleep, your body naturally recharges itself, which puts you at lower risk for cardiovascular problems and chronic conditions like diabetes, as well as improving your immune system.

Sleep also contributes to better brain function, memory, concentration and lower stress. According to the National Institutes of Health, most adults need 7-9 hours of sleep every night to achieve maximum health benefits.

If you’re falling short of the recommended amount of sleep, you may be able to make some adjustments that help you reap the health benefits of better rest. Learn what you can do to improve your sleep with these tips from the experts in safer, healthier sleep at Naturepedic.

Reduce Light Exposure
Your body’s natural circadian rhythms are closely aligned with light and dark. When your body senses light, it sends signals to your brain that it’s time to be awake. Light also suppresses your body’s production of melatonin, a hormone linked to sleep. Cutting back on bright lights and avoiding devices at least an hour before bed can tell your body it’s time to wind down, and sleeping in a dark room promotes better rest.

Invest in the Right Mattress
Your mattress plays a major role in your comfort through the night, so making sure it fits your needs is an important step toward getting better rest. Take control of your comfort with a quality mattress such as Naturepedic’s EOS (Ergonomic Organic Sleep) mattress, which is handcrafted and made without polyurethane foam, formaldehyde, flame retardants or fiberglass. The breathable layers of certified organic cotton, wool and GOTS-approved latex ensure better temperature regulation while naturally contouring the body. An added feature is the ability to customize each side of the bed by opening the zippers and adjusting the layered components for the perfect comfort combination.

Find the Right Sheets
Sheets that are too stiff, scratchy or otherwise unpleasant make it nearly impossible to settle in for a good night’s rest. Higher thread counts tend to be softer, higher quality sheets. However, you may need to experiment to find which material suits you best.

Set a Comfortable Temperature
When you’re too hot or cold, your mind tends to focus on those sensations rather than allowing you to slip into a slumber. Set your thermostat at a comfortable temperature, adding fans or adjusting the layers of bedding as necessary to achieve the perfect level of cozy comfort.

Use a Sound Machine
If you’re a light sleeper, noise can wreak havoc on your rest. Many people find sound machines offer two key benefits: They provide a soothing sound, such as rain or ocean waves, that allows you to relax and ease into slumber and constant background noise, so additional sounds are less disruptive.

Find more solutions for achieving better sleep at Naturepedic.com.

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What you should know about IBD

Two common conditions are irritable bowel syndrome (IBS) and inflammatory bowel disease (IBD). They’re often confused for one another, but these are actually two different GI disorders.

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It may not be something you like to talk about, but if you have gastrointestinal (GI) problems, your symptoms may be far more common than you think. According to data from the American Gastroenterological Association, 60-70 million people living in the United States have gut health concerns.

Two common conditions are irritable bowel syndrome (IBS) and inflammatory bowel disease (IBD). They’re often confused for one another, but these are actually two different GI disorders.

IBS is a syndrome; it is defined by a group of symptoms, does not cause inflammation and rarely requires hospitalization or surgery. IBD, on the other hand, is an umbrella term used to describe disorders that cause chronic inflammation of your GI tract.

The disease is more common than you may realize; a study led by the Crohn’s & Colitis Foundation found nearly 1 in 100 people living in the U.S. have IBD. The two most common forms of IBD are Crohn’s disease and ulcerative colitis.

Understanding IBD Symptoms
Because it poses serious health risks and can cause permanent damage to your intestines, it’s important to be aware of what IBD is and recognize the symptoms. Your primary care doctor or gastroenterologist can help if you have concerns about these symptoms:

  • Intense, crampy pain that doesn’t go away in a day or two or has been present on and off for weeks or longer
  • A notable change in bowel movement frequency, whether more or less often
  • Frequent diarrhea over several weeks, or loose stools multiple times a day
  • Frequent constipation, or constipation alternating with diarrhea
  • Urgency on a regular basis or inability to hold back the bowel movement before reaching the bathroom
  • Blood with bowel movements
  • Mucus in your stool regularly or paired with pain or other symptoms
  • Always feeling as though you aren’t fully emptying your bowels

Other symptoms that may have a variety of causes but need extra attention especially if you notice them along with any of the symptoms above include pain outside of the gut, fatigue, loss of appetite and weight loss. In addition, children with IBD may have delays in growth and the onset of puberty.

Diagnosing IBD
No single test can confirm a Crohn’s or ulcerative colitis diagnosis. Your medical history and information obtained from diagnostic testing can exclude other potential causes of your symptoms, since gastrointestinal symptoms are common and can have a variety of causes.

Your first tests will likely include blood and stool laboratory tests. Further testing could include imaging studies of your gastrointestinal tract or a look inside your GI tract through an endoscope.

Identifying Treatment Options
Once an IBD diagnosis is confirmed, you can partner with your doctor to manage your disease. Treatment plans are highly personalized, as what works for one person may not for another. Medication and managing your diet and nutrition are two common treatment recommendations. In some cases, surgery can help improve your quality of life.

Clinical trials may also be an option for treating your IBD. Through clinical trials, researchers find new ways to improve treatments and quality of life. In fact, clinical trials represent the final stages of a long and careful research process to make new and improved treatment options for patients available.

However, an important part of clinical trials for IBD is patient participation. Without the enrollment of patients in clinical trials, new treatment options for IBD can be delayed or never become available.

Equally important to this process is having a diverse representation of patients that considers race, age or other categories. This helps researchers develop treatments that meet the needs of a vast IBD patient community.

If you’re interested in participating in a clinical trial, ask your doctor to help you find a trial that is right for you, and visit crohnscolitisfoundation.org to learn more about IBD and treatment options, including clinical trials.

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Unlocking the science of sleep: How rest enhances language learning

Getting eight hours of sleep every night helps the brain to store and learn a new language.

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Sleep is critical for all sorts of reasons, but a team of international scientists has discovered a new incentive for getting eight hours of sleep every night: it helps the brain to store and learn a new language.

A study led by the University of South Australia (UniSA) and published in the Journal of Neuroscience has revealed that the coordination of two electrical events in the sleeping brain significantly improves our ability to remember new words and complex grammatical rules.

In an experiment with 35 native English-speaking adults, researchers tracked the brain activity of participants learning a miniature language called Mini Pinyin that is based on Mandarin but with similar grammatical rules to English.

Half of the participants learned Mini Pinyin in the morning and then returned in the evening to have their memory tested. The other half learned Mini Pinyin in the evening and then slept in the laboratory overnight while their brain activity was recorded. Researchers tested their progress in the morning.

Those who slept performed significantly better compared to those who remained awake.

Lead researcher  Dr Zachariah Cross, who did his PhD at UniSA but is now based at Northwestern University in Chicago, says sleep-based improvements were linked to the coupling of slow oscillations and sleep spindles – brainwave patterns that synchronise during NREM sleep.

“This coupling likely reflects the transfer of learned information from the hippocampus to the cortex, enhancing long-term memory storage,” Dr Cross says.

“Post-sleep neural activity showed unique patterns of theta oscillations associated with cognitive control and memory consolidation, suggesting a strong link between sleep-induced brainwave co-ordination and learning outcomes.”

UniSA researcher Dr Scott Coussens says the study underscores the importance of sleep in learning complex linguistic rules.

“By demonstrating how specific neural processes during sleep support memory consolidation, we provide a new perspective on how sleep disruption impacts language learning,” Dr Coussens says. “Sleep is not just restful; it’s an active, transformative state for the brain.”

The findings could also potentially inform treatments for individuals with language-related impairments, including autism spectrum disorder (ASD) and aphasia, who experience greater sleep disturbances than other adults.

Research on both animals and humans shows that slow oscillations improve neural plasticity – the brain’s ability to change and adapt in response to experiences and injury.

“From this perspective, slow oscillations could be increased via methods such as transcranial magnetic stimulation to accelerate aphasia-based speech and language therapy,” Dr Cross says.

In future, the researchers plan to explore how sleep and wake dynamics influence the learning of other complex cognitive tasks.

“Understanding how the brain works during sleep has implications beyond language learning. It could revolutionize how we approach education, rehabilitation, and cognitive training.”

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