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Dengue vaccine now available at select Watsons stores

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Dengvaxia, a vaccine against dengue, is now available over-the-counter nationwide at select stores of Watsons, the first retailer to offer the vaccine in the Philippines.

Watsons Dengue Vaccine KV 2

“We decided to offer dengue vaccination in our 108 selected stores nationwide as we recognize the importance of having vaccination accessible to Filipinos to protect them against dengue infection and make them healthier. It is our latest addition that we offer in our stores, aside from cervical cancer, flu and pneumonia vaccinations,” says Danilo Chiong, Watsons Trading Health Director.

Produced by pharmaceutical firm Sanofi Pasteur, Dengvaxia took over 20 years of extensive research and tests to develop. Studies on the vaccine were conducted on 41,000 people and were carried out in 15 countries including the Philippines. With test results fully reviewed by a committee of independent experts, the vaccine has been recommended by the World Health Organization (WHO).

In a WHO position paper published in July 29, 2016, it says that to prevent dengue infection, dengue vaccine should be a part of a comprehensive dengue control strategy, which include well-executed and sustained vector controls, evidence-based best practices for clinical care and strong dengue surveillance.

The vaccine has also been endorsed by the Philippine Society for Microbiology and infectious Diseases (PSMID) and Philippine College of Physicians (PCP). In February 2017, the vaccine got the approval to be administered in 14 countries, including the Philippines, where dengue is endemic.

In the Philippines, there were 211,106 reported dengue cases in 2016. The most number of cases was reported in Regions VI, VII, III, IV-A, and XII. All age groups were affected by dengue.

Age bracket and dosage

Since there is no specific treatment for dengue, Dr. Rontgene Solante, Past President at PSMID, said the dengue vaccine can protect individuals against the illness. It can be administered to individuals 9 to 45 years old living in endemic areas for prevention of dengue illness caused by dengue virus serotypes 1, 2, 3 and 4. It is to be taken in three doses of 0.5ml at six-month intervals to increase antibodies response, thereby protecting them from all four strains of the virus. The vaccine, when correctly administered in three doses, stays effective in four to five years.

The vaccine costs P4,000 per dose or P12,000 for all three doses, which is reasonable considering the high incidence of dengue and high cost of treatment in the Philippines.

“The vaccine is not just for kids but adults should also be vaccinated as this is safe and can modify infection. Don’t look at the price but in the long-term benefits it provides,” said Solante.

Solante, however, relayed the vaccine is not effective for children below nine years old. A study made on the vaccine and these children showed that the efficacy of the vaccine was below 50%. Likewise, the vaccine cannot be administered to persons over 45 years old as there was no study made yet about its effectiveness for these individuals.

Apart from these, other persons who have the following cannot take the vaccine: history of severe allergic reaction; congenital or acquired immune deficiency diseases; symptomatic HIV infection; and pregnant or breastfeeding women.

Solante, however, said that those were infected by dengue in the past can still avail of the vaccine.

Solante advised individuals to administer the vaccine correctly. “If a person who has taken the first dose fails to take the second dose on the scheduled (sixth) month, and instead take it, let’s say, on the eighth month, the vaccine is still effective. But, if he misses taking it for a couple of years, the vaccine became ineffective and has to start taking it all over again.”

The vaccine is injected in arms via the subcutaneous route over the deltoid region. How is it effective? In his presentation, Dr. Solante said the vaccine can result to 80.8% reduction in hospitalized dengue; 93.2% drop in severe dengue; and 65.6% decline in symptomatic dengue, which means that if a person is infected, symptoms are reduced.

The vaccine does not contain adjuvants or preservatives so the adverse effect or reaction is lower, according to Solante. Adverse reactions include headache, malaise, myalgia, pain, injection site reaction, and other mild to moderate reactions.

A study conducted by the University of the Philippines showed that the vaccine is expected to reduce dengue cases in the country by over 24% in a span of five years.

Meanwhile, Chiong said that they will have a doctor in over 100 selected Watsons stores to administer the vaccine during vaccination dates. The first scheduled dengue vaccination will be on April 30, 2017 (1st dose); October 29, 2017 (2nd dose) and April 29, 2018 (3rd dose). The second schedule vaccination will be on May 14, 2018 (1st dose); November 12, 2018 (2nd dose); and May 13, 2018 (3rd dose).

REYNALDO “Rey” R. VICENTE’s career experience involves mostly research in publishing companies. He previously held the position of Research and Events Director of Media G8way Corp., publisher of Computerworld Philippines (CWP), PC World Philippines, and IT Resource. He also handled events organized for CWP. Prior to this, he was a Research Head of a business publication. Now as co-publisher of Zest Magazine, Rey also serves as Managing Editor. Rey finished his bachelor’s degree majoring in Economics at the University of Santo Tomas.

Beauty & Fashion

Redefining aesthetics: From anti-aging to healthy aging

Growing attention is now being given to healthy aging, understanding how the entire face changes over time, preserving facial harmony, and helping people continue to look like themselves.

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For decades, “anti-aging” has defined the beauty and aesthetics conversation, promising to erase wrinkles and reverse the signs of time. Today, that conversation is shifting.

Aging is no longer just about looking younger. Growing attention is now being given to healthy aging, understanding how the entire face changes over time, preserving facial harmony, and helping people continue to look like themselves.

A review published in Facial Plastic Surgery, The Anatomy of the Aging Face: A Review, describes aging as changes across bone, ligaments, muscles, fat, and skin. Another review in Aesthetic Surgery Journal, The Facial Aging Process From the “Inside Out”, explains how changes beneath the surface eventually become visible on top.

Studies in Plastic and Reconstructive Surgery show facial fat is organized into distinct anatomical compartments that can lose volume and shift position over time, altering facial shape and balance.

For multi-awarded aesthetic physician Dr. James Co, founder of Cosma Institute and Architect of Aesthetic Confidence, these findings are the reason aesthetic care must start with understanding, not just treating.

“Aging is not a disease we need to cure,” Co said. “It is a biological process. As physicians, our role is to understand what is changing beneath the surface, how those changes differ from person to person, and whether intervention is appropriate in the first place.”

“When you only look at the wrinkle, you are looking at the surface of a much bigger anatomical process,” he added. “The face ages as a system. Good assessment means understanding what is happening underneath before deciding what should be done on the surface.”

Part of that understanding is recognizing that no two faces age the same way. Two people can be the same age and experience aging very differently. Genetics, skeletal structure, fat distribution, skin characteristics, sun exposure, lifestyle, and environmental factors all influence how aging presents.

“Two patients can be the same age and come to me with completely different anatomy, lifestyles, concerns, and goals,” Co said. “Why would we expect their treatment plans to look exactly the same?”

This is where healthy aging broadens the conversation — from fixing isolated signs to looking at the face as a whole and listening to what the individual actually wants.

“Someone can want to look refreshed without wanting to look 20 years younger,” Co said. “Those are completely different goals.”

Rather than trying to freeze one version of the face forever, healthy aging acknowledges that the face will continue to change. As different structures change at different rates, the relationship between features evolves. Facial harmony is therefore not fixed.

“You cannot freeze one version of your face forever,” Co said. “But you can understand how the face is changing and make decisions that respect its natural proportions and your identity.”

In the age of social media, where aesthetic treatments are highly visible, Co cautions against self-diagnosis.

“Patients should not have to diagnose themselves from social media,” he said. “You might recognize a concern, but deciding why it is happening and what should be done about it requires proper assessment.”

The shift is also about how people feel, not just how they look. A 2022 review on minimally invasive facial aesthetic procedures found studies are increasingly looking beyond physical changes to include satisfaction with appearance and aspects of psychological and social well-being, while noting that evidence still needs careful interpretation.

For Co, this reinforces that success is not always about looking dramatically younger.

“We need to ask whether the result makes sense for the patient, whether expectations were met, and whether we preserved the things that make that person recognizable,” he said. “I would rather someone tell my patient, ‘You look well,’ than immediately ask, ‘What did you have done?'”

At Cosma Institute, Co applies this consultation-led philosophy through individualized assessment, facial harmony, medical judgment, and patient education. Having trained aesthetic practitioners across Southeast Asia and Europe, he advocates for natural-looking outcomes that respect the characteristics already present in each face — an approach that recently earned him two awards at the Merz Aesthetics Tala Awards.

For Co, the evolution of aesthetic medicine is not about having more tools, but knowing when to use them — and when not to.

“Aging cannot be stopped, and I don’t think that should be the promise,” he said. “What we can do is understand it better. We can look at the science, understand the anatomy, listen to the patient, and make decisions that allow them to age while still looking recognizably like themselves.”

For Co, healthy aging begins not with fighting age, but with understanding it.

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The look and feel of your neighborhood may affect your sleep

Those living in neighborhoods rated as having a stronger sense of safety tended to sleep longer, and that this rating appeared to be shaped by the streetscape.

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Your neighborhood’s “streetscape”—the physical environment of your street—is something that you have probably never consciously thought about, despite seeing it every day. But what if the streetscape was affecting you on a subconscious level and disrupting your sleep? 

This intriguing question is posed by the findings of a study led by Professor Daisuke Matsushita of the Graduate School of Human Life and Ecology at Osaka Metropolitan University. The research team used AI to analyze more than 200,000 Google Street View images to identify visual neighborhood characteristics. They then linked these characteristics to the self-reported sleep of 1,089 working adults living on the lower floors of apartments in Tokyo, who were most likely to be affected by the streetscape.  

They found that those living in neighborhoods rated as having a stronger sense of safety tended to sleep longer, and that this rating appeared to be shaped by the streetscape. Generally, people slept longer in areas with lots of greenery, such as leafy trees, on the street. Similarly, high “enclosure”—meaning many tall vertical buildings and few wide-open spaces—was also associated with longer sleep and fewer insomnia symptoms. 

However, the study also made a surprising finding. The researchers found that highly walkable streetscapes, such as those with more sidewalks and traffic signs, were associated with a lowered sense of safety and shortened sleep duration.  

This suggests that walkability does not always represent a reassuring environment. Instead, a possible explanation is that streets with extensive pedestrian infrastructure are often busier, more crowded, and used by more strangers, which may be perceived as less safe or less relaxing than quieter residential streets.  

“This study demonstrates the potential for evaluating streetscape characteristics across large geographic areas in a cost-effective manner,” Dr. Matsushita said. “Based on the technique used in this study, cities could potentially measure perceived safety, beauty, liveliness, and enclosure as well as pollution and noise.”  

“We hope that opening up this new perspective creates further possibilities for designing healthier neighborhoods,” he concludes.  

The findings were published in Building and Environment.

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Workout or nap? Either can help your sleepless brain, study finds

People who either completed 20 minutes of moderate-to-vigorous exercise or took a 90-minute nap performed about 22 per cent better on memory tests after 30 hours without sleep than those who did neither.

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A short workout or a nap can help protect memory after a sleepless night, a McGill University-led study has found.

Researchers found people who either completed 20 minutes of moderate-to-vigorous exercise or took a 90-minute nap performed about 22 per cent better on memory tests after 30 hours without sleep than those who did neither. The findings, published in Proceedings of the National Academy of Sciences (PNAS), point to practical ways to counter the effects of sleep deprivation.

“Sleep loss affects nearly every aspect of how we think and function, but many people can’t simply stop what they’re doing and get more sleep,” said senior author Marc Roig, Professor in McGill’s School of Physical and Occupational Therapy. “Our findings show that even a brief bout of exercise may help preserve one of our most important cognitive abilities.”

The study involved 54 healthy young adults who stayed awake for 30 consecutive hours under lab supervision. Participants were then assigned to one of three groups: a 20-minute cycling session, a 90-minute nap or a control condition. Three days later, researchers tested their memory for images they had viewed immediately after the intervention. Those who exercised or napped remembered significantly more images than participants who did neither.

Same result, different pathways

While the memory benefits were nearly identical, brain recordings revealed that exercise and napping helped in different ways.

Napping appeared to help the brain recharge, making it easier to take in and remember new information. Exercise, by contrast, helped the brain use its remaining resources more efficiently, without making participants feel more tired.

The findings could eventually inform fatigue-management strategies in workplaces where sleep loss is common and mistakes can have serious consequences, such as health care, transportation and emergency response.

“A nap isn’t always possible in the middle of a shift,” said first author Madhura Lotlikar, a doctoral candidate in McGill’s Department of Neurology and Neurosurgery. “Exercise is accessible, inexpensive and easy to implement. That makes it a promising tool to help people stay cognitively sharp when sleep is limited.”

The researchers emphasize that exercise cannot replace sleep, but it may help people function better when getting enough rest isn’t possible.

About the study

“Protecting episodic memory after sleep loss: Similar benefits of exercise and naps via distinct neural contributions” by Madhura Lotlikar and Marc Roig et al., was published in Proceedings of the National Academy of Sciences of the United States of America.

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