NewsMakers
Positive life outlook may protect against middle-aged memory loss, 16-year study suggests
Those who said they had higher wellbeing were more likely to subsequently have better scores on memory tests.
Higher levels of wellbeing may help reduce the risk of memory loss in middle age, suggests new research, which tracked more than 10,000 over 50-year-olds across a 16-year span.
Findings that are published in the peer-reviewed journal Aging & Mental Health found those who said they had higher wellbeing were more likely to subsequently have better scores on memory tests.
These people – all of whom were determined as having ‘healthy brains’ – also reported a greater sense of control, independence, and freedom to make choices.
This association between psychological wellbeing and better recall was small but significant. The link was also independent of depressive symptoms, according to the researchers.
However, the analysis by a cohort of 15 experts across the UK, US and Spain found no evidence to suggest better memory was linked with later higher wellbeing, although the authors say the possibility cannot be discounted.
The academics add that the results highlight that psychological and social factors affect brain health, and wellbeing may protect against cognitive impairment. Interventions to promote psychological wellbeing such as mindfulness could maintain mental functions such as memory as people age.
“In the context of an ageing population, understanding factors that may protect and maintain healthy cognitive function is critical for enhanced population health and health policy development,” explains lead author Dr Amber John, a Lecturer in Psychology at the University of Liverpool and a current Alzheimer’s Research UK Fellow, who specialises in research on ageing, with a specific focus on mental health, neurodivergence, and dementia.
“While, in this research, we can’t examine and understand the relationship between causes and effects, determining if one event leads to another (causality), our findings are important in proposing that good wellbeing predates better memory rather than vice versa. This suggests that the link between wellbeing and memory is not just because people with poor memory have poor wellbeing and that, if causality is demonstrated, improving wellbeing could protect against subsequent memory decline.”
Co-author Joshua Stott, a Professor of Ageing and Clinical Psychology at UCL, adds: “This study represents an important step toward understanding the interplay between wellbeing and memory over time. It offers new insights into how self-rated wellbeing is associated with memory and vice versa.
“While our findings are preliminary, they highlight the importance of considering psychosocial influences on brain health such as memory.”
Depression and anxiety are widely recognised as risk factors in faster decline of brain health and dementia. A key global healthcare priority is now to prevent dementia.
Wellbeing is defined as emotional health combined with being able to function effectively. Happiness, confidence, a sense of purpose and control over life are among the elements of wellbeing.
Existing studies have suggested a positive link between wellbeing, age-related decline in mental processes in the brain, and mild impairment of these functions. Memory is regarded as a cornerstone of an individual’s mental processes.
However, most studies have only tested this link between wellbeing and memory in one direction or another. The aim of this research was to provide longer-term insights into the relationship between wellbeing and memory in people who have yet to experience significant cognitive decline.
Data was based on 10,760 men and women who took part in the English Longitudinal Study of Ageing Self-reported. This existing long-term research project involves UK adults over the age of 50 and includes attitudes to well-being.
Participants were assessed on wellbeing and memory every two years – a total of nine times during the 16-year study period stretching back to 2002.
Researchers used a learning task to check participants’ ability to recall ten words immediately and after a delay. Wellbeing was assessed using a quality-of-life questionnaire. Participants scored themselves based on satisfaction of specific needs – pleasure, control, autonomy, and self-realisation. Questions included ‘I can do the things that I want to do’, and ‘I feel that life is full of opportunities’.
The authors excluded anyone with a dementia diagnosis at the start of the study.
Results showed a small but significant association between higher wellbeing and better memory. In addition, the study found that the impact of wellbeing on memory was significant even after adjusting for depression. The authors say this suggests links between wellbeing and memory exist independent from depressive symptoms.
Biological factors such as cardiovascular disease and those linked to lifestyle – such as physical activities – are among possible reasons for the effect of wellbeing on memory, say the authors. Age, gender, lifestyle, and socioeconomic status may also have a negative or positive impact on the relationship between wellbeing and memory function.
Despite the lack of evidence for memory affecting wellbeing, the authors say this cannot be ruled out. They say lower psychological wellbeing may be a sign of ‘oncoming cognitive impairment’ before symptoms become apparent.
The research was funded by Alzheimer’s Research UK; Medical Research Council (a part of UKRI); National Institute on Aging; and National Institute for Health and Care Research (NIHR).
Emma Taylor, Information Services Manager at Alzheimer’s Research UK, comments: “Loving your heart, staying sharp and keeping connected are key to protecting our brain health as we age.
“There are 14 established health and lifestyle risk factors for dementia, including lack of physical exercise, social isolation, and depression, which are linked to wellbeing.
“This study found that people over 50 who reported they felt happier and more fulfilled in life had a better memory over time. However, this research is observational – and more work is needed to understand how a positive wellbeing and memory are connected and whether this has a knock-on effect on dementia risk.
“Looking after our mental wellbeing plays an important part in our overall health. And it’s never too late to start taking steps to keep our brains healthy throughout our lives and lessen the devastating impact of dementia.”
As with all long running longitudinal studies, one limitation of this paper is sample attrition over the follow-up period. However, the team used a research methodology which enabled use of use of all available information in the observed data, without imputation or discarding cases.
To conclude, authors say their results could provide the basis for further research into what factors can enhance brain health in aging populations.
Co-author Dr Emily Willroth, an Assistant Professor of Psychological & Brain Sciences at Washington University, in St Louis, Missouri, adds: “Going forwards it would be fantastic if this research can build on the foundations of ongoing memory research to potentially inform strategies supporting cognitive health in ageing populations – that is the aim.”
NewsMakers
For weight loss, where food comes from may matter as much as how it is processed
Processed and ultra-processed animal foods tended to track with weight gain, and minimally processed plant foods with weight loss, although these associations were weaker. Ultra-processed plant foods were not associated with weight change.
Eating more meat, fish, eggs, and dairy products was associated with weight gain even when those foods were minimally processed, according to a study from the Physicians Committee for Responsible Medicine published in Nutrition Research. Minimally processed plant foods, such as fruits, vegetables, whole grains, and beans, showed the opposite pattern.
“Ultra-processed foods get most of the blame for weight gain, but our results suggest we also need to ask whether a food comes from a plant or an animal,” says lead author Hana Kahleova, MD, PhD, director of clinical research at the Physicians Committee. “A chicken breast is minimally processed. So is an apple. In our study, they did not move the scale in the same direction.”
The researchers analyzed data from a randomized crossover trial in which 62 adults with overweight followed a Mediterranean diet, rich in olive oil, fish, and nuts, and a low-fat vegan diet for 16 weeks each, separated by a four-week washout. Participants kept three-day diet records, and every food was classified by degree of processing, using the NOVA system, and by whether it came from a plant or an animal.
Compared with the Mediterranean diet, the vegan diet cut minimally processed animal foods by 135 grams per day more and raised minimally processed plant foods by 202 grams per day more. Processed animal and plant foods also fell more on the vegan diet. Across both diets, eating more minimally processed animal foods was linked to weight gain; this was the strongest association in the analysis and the only one to remain statistically significant after correction for multiple comparisons.
Processed and ultra-processed animal foods tended to track with weight gain, and minimally processed plant foods with weight loss, although these associations were weaker. Ultra-processed plant foods were not associated with weight change.
In the main trial, published in 2022, participants lost an average of 6 kilograms (about 13 pounds) on the vegan diet, with no change on the Mediterranean diet. Minimally processed plant foods are high in fiber and water and low in calorie density, which helps people feel full on fewer calories.
“If you want to lose weight, fill your plate with beans, vegetables, fruits, and whole grains, and leave the animal products off,” says Dr. Kahleova. “The degree of processing still matters, but it is not the whole story.”
NewsMakers
Mindfulness and self-compassion can alleviate premenstrual symptoms
It is estimated that PMS affects approximately 20-30% of menstruating people, while PMDD impacts 3-8%. The scale of the problem is significant, yet the psychological factors that protect against the development of these symptoms have not been thoroughly investigated.
A kind attitude toward oneself and practicing mindfulness can improve functioning in individuals who experience severe premenstrual symptoms, according to a study by psychologists from SWPS University and Jagiellonian University.
Premenstrual syndrome (PMS) and its more severe form, premenstrual dysphoric disorder (PMDD), cause distressing psychological and physical symptoms, including mood swings, fatigue, concentration difficulties, headaches, and muscle pain. These ailments occur during the second phase of the menstrual cycle and interfere with daily functioning, affecting education, work, relationships, and overall quality of life.
Up to 30 percent of women affected
It is estimated that PMS affects approximately 20-30% of menstruating people, while PMDD impacts 3-8%. The scale of the problem is significant, yet the psychological factors that protect against the development of these symptoms have not been thoroughly investigated.
The study, published in “Psychology and Psychotherapy: Theory, Research and Practice”, is part of a broader project analysing potential mechanisms and factors that may protect against the onset of PMS and PMDD. In a new study, Rachela Antosz-Rekucka, PhD, a psychologist at the Institute of Psychology at SWPS University, and Katarzyna Prochwicz, PhD, a professor at the Institute of Psychology of the Jagiellonian University, analysed factors that might protect against the onset of severe premenstrual symptoms. They examined variables such as the sense of coherence, mindfulness skills, and self-compassion, and investigated their relationship with past trauma, perceived stress levels, and symptoms of premenstrual disorders.
The study involved 228 participants aged 18 to 52. They were asked about their past experiences with premenstrual symptoms, and a part of the group subsequently tracked their symptoms over the course of two menstrual cycles.
Self-compassion and mindfulness help alleviate symptoms
The results suggest that higher levels of certain psychological resources can moderate the negative effect of stress and trauma on the severity of menstrual cycle-related symptoms.
Specific psychological attitudes may noticeably reduce the impact of daily stress on the severity of premenstrual symptoms. These include a kind attitude toward oneself and the acceptance of difficult moments, known as self-compassion. This approach helps women to navigate the challenging phases of their cycle more easily, even during times of intense nervous tension, says Rachela Antosz-Rekucka of SWPS University, who conducted the study as part of her doctoral research at the Jagiellonian University.
Practicing mindfulness (directing one’s attention to the present moment without judgment or worry) can also offer relief. In the context of PMS and PMDD, refraining from judging one’s own emotional reactions is particularly helpful, as it prevents the magnification of perceived discomfort. Furthermore, individuals with a strong sense of coherence cope better with rising premenstrual stress.
Past trauma and premenstrual symptoms
For individuals with a history of trauma, the ability to precisely describe their internal states and feelings, combined with the capacity to avoid judging their own emotional reactions, can help mitigate the negative impact of that trauma on premenstrual symptoms.
Psychological resources boost stress resilience
The results of the study could be significant for many people who menstruate. These findings could pave the way for modern therapeutic programs based on approaches such as mindfulness training or self-compassion-focused therapy, potentially reducing the reliance on medication.
The study suggests that more understanding, mindful, and compassionate attitude towards oneself may benefit individuals with severe premenstrual symptoms. PMS and PMDD are chronic conditions, which is why interventions such as mindfulness-based therapy, compassion-focused therapy, or strategies oriented at enhancing the sense of coherence, may help individuals navigate their conditions more effectively, and possibly increase their overall quality of life, Rachela Antosz-Rekucka emphasises.
NewsMakers
Music can enhance the flavor of your food
The brain does not create flavor based solely on signals from the tongue.
The moment we take a sip of our morning coffee or our first bite of lunch, the brain begins interpreting what we taste. Is it sweet? Sour? Or something else entirely?
But the brain does not create flavor based solely on signals from the tongue. That is the finding of a new study from the Department of Food Science, published in the scientific journal Scientific Reports.
“When music reaches the ears at the same time as we are eating, we can see that the brain responds more strongly than when taste is experienced without music,” says first author and postdoctoral researcher Alberte Baggesgaard Seeberg from the Department of Food Science.
Using brain scans, the researchers show that music can activate some of the same brain regions involved in processing taste.
“This tells us that flavour is not simply a property of food. Flavor is an experience created by the brain,” says senior author and associate professor Janice Wang.
A breakthrough in brain imaging
This is the first time researchers have used brain imaging to show what happens in the brain when it processes taste. In the study, they used functional magnetic resonance imaging (fMRI), which measures activity in different parts of the brain by detecting changes in blood flow.
“This allows us to move beyond simply asking people about their experiences, which has been the approach in previous studies. With brain scans, we gain a biological window into what happens when the senses interact,” says Alberte Baggesgaard Seeberg.
While participants lay in the scanner, their brain activity was measured under different conditions. In some cases, they listened only to music. In others, they tasted flavor solutions. In some trials, music and taste were presented simultaneously. This enabled the researchers to compare how the brain responds to sound and taste separately and in combination.
The results clearly showed that certain brain regions were more active when participants listened to music while tasting one of the two flavor solutions.
“We can see that flavor is constructed by the brain and not only by the taste buds. What determines flavor is not limited to what happens on the tongue. It emerges through the integration of multiple senses,” says Janice Wang.
The findings build on previous studies showing that music can enhance particular taste perceptions. For example, slow pop music with harmonious tones may enhance sweetness. Until now, however, this has only been investigated through behavioral studies in which participants rated flavours with and without music.
Shaping flavor experiences could improve wellbeing
According to the researchers, the new knowledge could be used to design better eating experiences in a range of settings, including restaurants, canteens and hospitals.
“For people who are at risk of malnutrition, something as simple as music could potentially improve the eating experience. There is a great deal we can do, often at very little cost, to improve quality of life for some people,” says Alberte Baggesgaard Seeberg.
Janice Wang is pleased that, after many years of research into flavour and sensory perception, the team can now present biological evidence of how the senses interact.
“We now have a new way of influencing flavor perception, creating a better meal experience and potentially a better overall experience, without necessarily changing the food itself,” she says.
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