Connect with us

NewsMakers

Multiple long-term physical health problems increase risk of depression later in life

The study showed that people with three physical health conditions had almost double the odds of developing depression later in life compared to those with one or no physical health conditions. The risk of future depression increased proportionally with the number of physical health conditions.

Published

on

Photo by Lucas Sankey from Unsplash.com

Published in The Lancet Regional Health – Europe and part-funded by National Institute for Health Research (NIHR) Maudsley Biomedical Research Centre, a study identified that people with multiple respiratory conditions were most likely to develop depression and anxiety later on. This has possible implications for future healthcare services if the Covid-19 pandemic brings about increases in long-term respiratory issues.

The study confirms the importance of integrating mental health support early into care plans for those with multiple physical health conditions. This is the first study of this scale to assess how specific patterns of physical health conditions are associated with common mental health conditions later in life, including anxiety.

Lead author, Dr Amy Ronaldson from the Institute of Psychiatry, Psychology & Neuroscience (IoPPN) at King’s College London said: “Our large-scale analysis has shown that people with two or more physical health conditions are at greater risk of developing depression and anxiety later in life, compared with those who have none or one physical health condition. What is really interesting is that this risk seems to be greater in those with certain combinations of physical conditions, which has implications for how the integration of mental and physical healthcare should be implemented.”

Previous research has established a relationship between multiple physical health problems and poor mental health but little is known about how specific patterns of physical health conditions precede the development of depression and anxiety.

The study analyzed data from UK Biobank on over 150,000 middle-aged people to investigate the relationship between physical health multimorbidity measured at one timepoint and depression and anxiety assessed four to six years later. The research factored in the influence of variables such as age, gender and socio-economic status.

The study showed that people with three physical health conditions had almost double the odds of developing depression later in life compared to those with one or no physical health conditions. The risk of future depression increased proportionally with the number of physical health conditions.

Those with a number of respiratory health conditions such as asthma and emphysema, had the greatest odds of experiencing depression later: more than three times the odds of those with no physical multimorbidity. Patterns of long-term health conditions where gastro-intestinal conditions such as IBS co-occured with painful conditions such as back pain or arthritis were also strong predictors of developing depression.

The study also investigated the relationship between multimorbidity and later experiences of anxiety and found similar results to depression in that two or more physical health conditions increased the odds of developing anxiety later in life.

Senior author, Dr Alexandru Dregan from the IoPPN said: “The finding that the different patterns of physical health conditions confer different levels of risk of later developing depression and anxiety could help inform services as to which patients require which kind of support.”

Further research is needed to investigate the mechanisms that link the different clusters with depression and anxiety, which can ultimately help develop better approaches to supporting those with long term conditions better and providing more integrated care.

Contributing author and Consultant Psychiatrist at South London and Maudsley NHS Foundation Trust, Dr Jayati Das-Munshi said: “We are gaining more insight into the links between mental and physical health and this study provides important insight into which combinations of long term health conditions are related to depression and anxiety. Through the use of approaches that integrate care for physical and mental health we may be able to help lessen the impact of multiple physical health problems.”

Zest Magazine accepts contributions promoting everything about living the good life (and how to make this so). C'mon, give us a yell.

NewsMakers

The look and feel of your neighborhood may affect your sleep

Those living in neighborhoods rated as having a stronger sense of safety tended to sleep longer, and that this rating appeared to be shaped by the streetscape.

Published

on

Your neighborhood’s “streetscape”—the physical environment of your street—is something that you have probably never consciously thought about, despite seeing it every day. But what if the streetscape was affecting you on a subconscious level and disrupting your sleep? 

This intriguing question is posed by the findings of a study led by Professor Daisuke Matsushita of the Graduate School of Human Life and Ecology at Osaka Metropolitan University. The research team used AI to analyze more than 200,000 Google Street View images to identify visual neighborhood characteristics. They then linked these characteristics to the self-reported sleep of 1,089 working adults living on the lower floors of apartments in Tokyo, who were most likely to be affected by the streetscape.  

They found that those living in neighborhoods rated as having a stronger sense of safety tended to sleep longer, and that this rating appeared to be shaped by the streetscape. Generally, people slept longer in areas with lots of greenery, such as leafy trees, on the street. Similarly, high “enclosure”—meaning many tall vertical buildings and few wide-open spaces—was also associated with longer sleep and fewer insomnia symptoms. 

However, the study also made a surprising finding. The researchers found that highly walkable streetscapes, such as those with more sidewalks and traffic signs, were associated with a lowered sense of safety and shortened sleep duration.  

This suggests that walkability does not always represent a reassuring environment. Instead, a possible explanation is that streets with extensive pedestrian infrastructure are often busier, more crowded, and used by more strangers, which may be perceived as less safe or less relaxing than quieter residential streets.  

“This study demonstrates the potential for evaluating streetscape characteristics across large geographic areas in a cost-effective manner,” Dr. Matsushita said. “Based on the technique used in this study, cities could potentially measure perceived safety, beauty, liveliness, and enclosure as well as pollution and noise.”  

“We hope that opening up this new perspective creates further possibilities for designing healthier neighborhoods,” he concludes.  

The findings were published in Building and Environment.

Continue Reading

NewsMakers

Workout or nap? Either can help your sleepless brain, study finds

People who either completed 20 minutes of moderate-to-vigorous exercise or took a 90-minute nap performed about 22 per cent better on memory tests after 30 hours without sleep than those who did neither.

Published

on

A short workout or a nap can help protect memory after a sleepless night, a McGill University-led study has found.

Researchers found people who either completed 20 minutes of moderate-to-vigorous exercise or took a 90-minute nap performed about 22 per cent better on memory tests after 30 hours without sleep than those who did neither. The findings, published in Proceedings of the National Academy of Sciences (PNAS), point to practical ways to counter the effects of sleep deprivation.

“Sleep loss affects nearly every aspect of how we think and function, but many people can’t simply stop what they’re doing and get more sleep,” said senior author Marc Roig, Professor in McGill’s School of Physical and Occupational Therapy. “Our findings show that even a brief bout of exercise may help preserve one of our most important cognitive abilities.”

The study involved 54 healthy young adults who stayed awake for 30 consecutive hours under lab supervision. Participants were then assigned to one of three groups: a 20-minute cycling session, a 90-minute nap or a control condition. Three days later, researchers tested their memory for images they had viewed immediately after the intervention. Those who exercised or napped remembered significantly more images than participants who did neither.

Same result, different pathways

While the memory benefits were nearly identical, brain recordings revealed that exercise and napping helped in different ways.

Napping appeared to help the brain recharge, making it easier to take in and remember new information. Exercise, by contrast, helped the brain use its remaining resources more efficiently, without making participants feel more tired.

The findings could eventually inform fatigue-management strategies in workplaces where sleep loss is common and mistakes can have serious consequences, such as health care, transportation and emergency response.

“A nap isn’t always possible in the middle of a shift,” said first author Madhura Lotlikar, a doctoral candidate in McGill’s Department of Neurology and Neurosurgery. “Exercise is accessible, inexpensive and easy to implement. That makes it a promising tool to help people stay cognitively sharp when sleep is limited.”

The researchers emphasize that exercise cannot replace sleep, but it may help people function better when getting enough rest isn’t possible.

About the study

“Protecting episodic memory after sleep loss: Similar benefits of exercise and naps via distinct neural contributions” by Madhura Lotlikar and Marc Roig et al., was published in Proceedings of the National Academy of Sciences of the United States of America.

Continue Reading

NewsMakers

Study links coffee consumption to metabolic health and sex hormones

Despite having a similar body mass index (BMI), individuals with higher coffee consumption had lower total and visceral fat and greater skeletal muscle mass than those who consumed less coffee.

Published

on

Coffee is one of the world’s most widely consumed beverages, and previous research has linked its consumption to a lower risk of conditions such as type 2 diabetes and cardiovascular disease. However, the biological mechanisms behind these benefits remain unclear. A new Finnish study links habitual coffee consumption to healthier body composition and metabolic markers, while revealing distinct associations with sex hormones in men and women.

The study, conducted at the University of Oulu, analysed data from 2,264 participants aged 46 in the Northern Finland Birth Cohort 1966. Researchers examined how habitual coffee consumption was associated with circulating metabolites, cardiometabolic risk markers and sex hormones.

Despite having a similar body mass index (BMI), individuals with higher coffee consumption had lower total and visceral fat and greater skeletal muscle mass than those who consumed less coffee.

In both men and women, higher coffee consumption was correlated with lower circulating levels of branched-chain amino acids, biomarkers that have previously been linked to insulin resistance and an increased risk of type 2 diabetes when chronically elevated.

The strongest sex-specific associations were observed in men. Higher coffee consumption was linked to a more favourable glucose–insulin profile, higher concentrations of total and bioavailable testosterone, and increased levels of sex hormone-binding globulin (SHBG). At the same time, free testosterone and the free androgen index were modestly lower. In women, hormonal associations were more limited and were primarily characterised by higher SHBG and lower measures of free androgens.

“Coffee is consumed by millions of people every day, yet we still know surprisingly little about how it relates to our metabolism and hormones. What stood out in our findings was a distinct hormonal signature that didn’t disappear even after we took into account BMI and lifestyle factors, with several of these associations differing between men and women,” says Luca Verroest, lead author of the study and Doctoral Researcher at the University of Oulu.

The results suggest that hormonal pathways may partly explain the relationship between coffee consumption and metabolic health. However, as this was an observational study, the findings demonstrate associations rather than cause-and-effect relationships.

The study is particularly relevant in Finland, one of the world’s highest coffee-consuming countries, where annual consumption averages around 11.8 kilograms per person.

The researchers say the findings provide a foundation for future studies aimed at determining whether coffee itself drives these biological changes and identifying the compounds responsible. These questions are currently being investigated in animal models, with the long-term goal of progressing to human intervention studies. Further research will be needed before the findings could inform dietary recommendations.

The study, Associations of habitual coffee intake with testosterone and cardiometabolic markers: the Northern Finland Birth Cohort 1966 study, has been published in the European Journal of Nutrition.

Continue Reading

Most Popular

Copyright ©FRINGE PUBLISHING. All rights reserved.