NewsMakers
Hearing loss linked to heightened heart failure risk
Both the participants who used hearing aids and those with poor hearing had a similarly significant increase in the risk of incident [heart failure], suggesting that while hearing aids can improve auditory function, they may not address the underlying vascular issues that contribute to the risk of [heart failure].

Hearing loss is linked to a heightened risk of developing heart failure, with the psychological distress caused by the impairment taking a key role in the observed association, finds a large long term study, published online in the journal Heart.
Hearing loss is increasingly common, particularly as people age, while the prevalence of heart failure is also on the rise, affecting around 64 million people worldwide, note the researchers.
While impaired hearing is associated with an increased risk of cardiovascular disease, principally, it is thought, as a result of the resulting social detachment, no study has comprehensively examined the association between objectively measured hearing ability and the risk of developing heart failure.
In a bid to plug this knowledge gap, the researchers mined the data of 164,431 participants from the UK Biobank, 4369 of whom wore hearing aids. None had heart failure to begin with. The average age of participants was 56, and 89,818 (around 55%) were women.
Their hearing ability was objectively measured using the validated Digit Triplets Test and the speech-reception-threshold (SRT). Participants (160,062) who didn’t wear hearing aids were categorised into three groups according to their performance on the DTT: normal (140,839; 88%); insufficient (16,759;10.5%); and poor (2464; 1.5%).
Comprehensive background information on current health, lifestyle, and psychosocial factors was collected via questionnaires.
Social isolation was assessed using a composite definition in the UK Biobank derived from scores (1-3) for the number of people living in the household, frequency of friend or family visits, and leisure or social activities. Those with a score of 2 or 3 were classified as socially isolated.
Psychological distress was assessed using a four-item version of the Patient Health Questionnaire (PHQ-4), with a score ranging from 0 to 12. Neuroticism, a depression-related personality trait, was assessed using 12 questions from the Eysenck Personality Questionnaire-Revised Short Form.
The development of heart failure among those who were not genetically predisposed to the condition was identified through medical records and death certificates during an average follow up of 11½ years.
During this period, 4449 (nearly 3%) of the participants developed heart failure. SRT levels were significantly positively associated with the risk of developing the condition in participants who didn’t wear hearing aids.
Compared with those with normal hearing, the adjusted heightened risks of developing heart failure were 15% and 28%, respectively, for insufficient and poor hearing, and 26% for hearing aid use.
The associations between SRT levels and heart failure risk were stronger in those without coronary heart disease or stroke at the start of the study.
SRT levels were significantly positively associated with social isolation, psychological distress, and neuroticism among those who didn’t wear hearing aids. And these factors had a substantial role in the observed associations in participants who didn’t wear hearing aids, accounting for 3%, 17%, and 3%, respectively, of the heightened risk of heart failure development.
When the scores for social isolation, psychological distress, and neuroticism were combined among those who had full data on these factors, the total mediating effect was just over 9%.
This was less than the sum of the mediating effects of each individual factor, which amounted to 19.5%, suggesting overlap and interaction between these three factors, say the researchers.
This is an observational study, and as such, can’t establish cause and effect. And data on hearing were collected only at the start of the study, while the participants in the current study were mainly of European descent and healthier than the UK general population, they acknowledge.
But there are plausible biological explanations for their findings, they say. “The rich distribution of capillaries in the…cochlea and the high metabolic demand of the inner ear may render these regions more sensitive to systemic vascular disorders rather than just local circulatory issues,” they suggest.
“Therefore, hearing impairment may reflect vascular health and serve as an early and sensitive predictor of cardiovascular disease, including [heart failure],” they add.
“Of note, both the participants who used hearing aids and those with poor hearing had a similarly significant increase in the risk of incident [heart failure], suggesting that while hearing aids can improve auditory function, they may not address the underlying vascular issues that contribute to the risk of [heart failure],” they continue.
And they explain: “Because hearing problems can lead to difficulties in speech comprehension and poor engagement in social activities, people with hearing impairment are more likely to experience social isolation, psychological distress, anxiety and depression than people without hearing impairment.
“These psychological factors may increase the activity of the sympathetic nervous system and the hypothalamic-pituitary adrenal axis, and enhance inflammation and oxidative stress, thereby accelerating atherosclerosis, increasing peripheral stress, and promoting the development of cardiac remodelling.”
The findings highlight the importance of integrating hearing health assessments into broader cardiovascular risk evaluation frameworks, they conclude. And strengthening psychological intervention in people with hearing impairment may be key to curbing the risk of heart failure, they suggest.
NewsMakers
Women non-smokers around 50% more likely than men to develop COPD
Smoking is the principal cause of COPD. But despite significant falls in cigarette smoking over the past 50 years, it remains a leading cause of death, with the prevalence of COPD in women approaching that of men, say the researchers.

Women’ are around 50% more likely than men to develop COPD, the umbrella term for chronic lung conditions, such as emphysema and bronchitis, even if they have never smoked or smoked much less than their male counterparts, suggests observational research, published in the open access journal BMJ Open Respiratory Research.
The findings challenge the widely held belief that women’s increased vulnerability to cigarette smoke likely explains this disparity, conclude the researchers.
Smoking is the principal cause of COPD. But despite significant falls in cigarette smoking over the past 50 years, it remains a leading cause of death, with the prevalence of COPD in women approaching that of men, say the researchers.
Women with COPD tend to have more severe symptoms, and at a younger age, than their male counterparts, prompting the suggestion that the explanation may lie in a heightened susceptibility to the effects of cigarette smoke, explain the researchers.
To clarify the associations between gender, cigarette smoke, and COPD, and to update previous estimates of the prevalence and impact of COPD, the researchers drew on a large nationally representative US survey of adults from the 2020 National Health Interview Survey (NHIS).
Respondents (12,638 women and 10,390 men aged at least 40) were asked about their smoking history, what tobacco products they used, and whether they vaped.
Women reported lower rates of both current and former cigarette, cigar, and pipe smoking, and smokeless tobacco use than men, but similar rates of vaping.
The prevalence of COPD was just under 8% for women and 6.5% for men. Women with COPD were more likely to have never smoked cigarettes than men with COPD (26.5% vs just over 14%), and less likely to use other tobacco products except for e-cigarettes (26.5% vs 20%).
Women also reported smoking fewer daily cigarettes than men, averaging around 18 compared with around 22, and to have done so for fewer years. And they were less likely than men to have started smoking before the age of 15:19% vs 28%.
Yet the prevalence of COPD was higher among women who had ever smoked than it was among men: 16% vs 11.5%. And among women who had never smoked the prevalence of COPD was almost twice as high as it was in male non-smokers: just over 3% compared with just over 1.5%.
In further analysis, female gender was associated with a significantly (47%) higher risk of being diagnosed with COPD after accounting for potentially influential factors.
This gender difference in risk persisted, irrespective of smoking history: among those who had never smoked, women were 62% more likely to be diagnosed with COPD, and among those who had ever smoked they were 43% more likely to do so.
The researchers acknowledge that their study relied on self report rather than objectively measured data. And they lacked potentially important information on hormonal influences, family history, or infectious, occupational, and environmental exposures.
But they nevertheless suggest: “These findings should raise questions about whether differing susceptibility to tobacco smoke is the key factor driving the increased COPD prevalence in women in the USA.
“If women were more susceptible to the effects of smoking, we would not expect to see a nearly identical risk per 10 pack-year exposure, nor would we expect to see a similarly increased relative risk among those who had never smoked.”
And they conclude: “Our findings refine prior estimates of COPD among those without a smoking history and re-emphasise the high burden of COPD in women, underscoring the need for thoughtful efforts to prevent, diagnose, and treat their disease.”
NewsMakers
Research suggests drinking coffee may reduce the risk of frailty
Habitual coffee consumption of 4-6 cups and over* (with one cup measuring at 125ml) per day is associated with a reduced risk of frailty.

A new study published in the European Journal of Nutrition has suggested that habitual coffee consumption of 4-6 cups and over* (with one cup measuring at 125ml) per day is associated with a reduced risk of frailty.
The study, funded by the Institute for Scientific Information on Coffee (ISIC) is the first to analyze the relationship between coffee consumption and the underlying components of frailty.
Coffee consumption has previously been linked to reducing the risk of some of the natural symptoms of ageing, such as improving cognitive function2 and mitigating against inflammatory related diseases. This latest research adds to the growing knowledge base within this area, exploring the benefits of regular coffee consumption over an extended period of time.
For this study, researchers conducted a detailed analysis over a long seven-year follow-up period, surveying 1,161 adults aged 55+ years through the Longitudinal Aging Study Amsterdam (LASA).
The relationship between coffee consumption and the presence and incidence of frailty was investigated. Frailty status was evaluated using Fried’s five-component frailty phenotype4,which is defined by the presence of three or more of the following symptoms: weight loss, weakness, exhaustion, slow gait (walking) speed, and low physical activity.
The results of this study indicate that higher habitual coffee consumption is associated with lower overall odds of frailty. These findings can be considered alongside the European Food Safety Authority’s (EFSA) scientific opinion that up to 400mg of caffeine (3-5 cups of coffee) per day is a moderate and safe amount5.
The researchers explain that coffee’s effect on reducing frailty can partly be attributed to the role of antioxidants in coffee, which may help to reduce inflammation, sarcopenia (muscle loss), and prevention of muscle damage. Coffee may also help to improve regulating insulin sensitivity and glucose uptake in older people.
The study’s lead author, Margreet R. Olthof, Associate Professor at the Amsterdam Public Health Research Institute, Vrije Universiteit Amsterdam, commented: “Drinking coffee is a key part of many people’s daily routine, and as people age they are constantly looking for ways to maintain their health. Our findings highlight the possible beneficial association between daily coffee consumption and reduced risk of frailty in later life in the older population. Coffee consumption may thus enhance healthy aging, but it is important we also explore further dietary interventions, to ensure older adults can continue to live fulfilling lives.”
* Moderate coffee consumption can be defined as 3–5 cups per day, based on the European Food Safety Authority’s review of caffeine safety.
NewsMakers
Landers opens first Cavite store in Vermosa
Landers Superstore, the fastest growing membership store in the country, proudly marks another milestone with the grand opening of Landers Vermosa – its first-ever store in the province and its 15th store nationwide.

Premium membership shopping has finally arrived in Cavite.
Landers Superstore, the fastest growing membership store in the country, proudly marks another milestone with the grand opening of Landers Vermosa – its first-ever store in the province and its 15th store nationwide.
Conveniently located inside Ayala Vermosa’s sprawling estate and lifestyle hub in Imus, Cavite, the newest Landers store offers a fresh and elevated way of shopping for Caviteños, complete with massive savings, world-class finds, and exclusive membership perks, all under one roof. It is also the largest Landers store to date at 12,900 sqm, promising a bigger and better experience for every member who walks through its doors.
Welcoming Landers in Cavite
Landers Vermosa opened with an exciting grand launch that brought together members of the media, content creators, and special guests for a first look at the newest and biggest Landers Superstore. The attendees were in high spirits as they explored the spacious store and enjoyed exclusive product samplings and guided tours.
During the event, Landers Deputy Chief Executive Officer Bill Cummings delivered heartfelt opening remarks, expressing his excitement for the new store and his appreciation for the warm welcome from the Cavite community, noting that over 60,000 members had already signed up prior to opening day – a clear sign of the anticipation surrounding the launch.
The celebration also highlighted the strong collaboration between Landers Superstore and Ayala Land, along with the support of the city government of Imus, led by Mayor Alex Advincula. The event underscored Landers’ commitment to bringing world-class shopping experiences to more Filipino families, starting with the vibrant and growing community in Cavite.
What to expect at Landers Vermosa
At Landers Vermosa, members can look forward to filling their carts with high-quality local and imported products—from daily essentials to unique international finds. Beyond shopping, the store offers a host of exclusive perks that make every visit more rewarding. Members can enjoy free haircuts or blow-dry services at Federal Barbers, low-priced medicine and wellness products at Capital Care Pharmacy, up to P10 off per liter at Landers-Caltex gas stations, and up to 50% off on Solane LPG refills.
Members of Landers Vermosa will gain access to all of Landers Superstore’s massive sale events like Super Crazy Sale and 50% Off Produce Sale, which offer unbeatable savings on a wide range of products. To complete the experience, members can enjoy regular in-store activities every month and free product samplings that are perfect for the whole family.
Sign up for Landers membership
Be among the first to explore this exciting new shopping destination and enjoy all the perks that come with being a Landers member.
If you’re not yet a member, now’s the perfect time to sign up! Memberships are currently on sale at 50% off—just P350 for a full year of exclusive savings and benefits. Promo runs until May 31.
Looking for even more value? Apply for the Landers Cashback Everywhere Credit Card and get up to 5% cashback on all Landers purchases, plus earn rewards wherever you shop.
Landers Vermosa is here with more perks, more savings, and more reasons to love shopping in the South. See you in-store.
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