NewsMakers
Eating only during daytime could protect people from heart risks of shift work
When it comes to cardiovascular health, food timing could be a bigger risk factor than sleep timing.

A study led by researchers at Mass General Brigham suggests that, when it comes to cardiovascular health, food timing could be a bigger risk factor than sleep timing
Numerous studies have shown that working the night shift is associated with serious health risks, including to the heart. However, a new study from Mass General Brigham suggests that eating only during the daytime could help people avoid the health risks associated with shift work. Results are published in Nature Communications.
“Our prior research has shown that circadian misalignment – the mistiming of our behavioral cycle relative to our internal body clock – increases cardiovascular risk factors,” said senior author Frank A.J.L. Scheer, PhD, a professor of Medicine and director of the Medical Chronobiology Program at Brigham and Women’s Hospital, a founding member of the Mass General Brigham healthcare system. “We wanted to understand what can be done to lower this risk, and our new research suggests food timing could be that target.”
Animal studies have shown that aligning food timing with the internal body clock could mitigate the health risks of staying awake during the typical rest time, which prompted Scheer and his colleagues to test this concept in humans.
For the study, researchers enlisted 20 healthy young participants to a two-week in-patient study at the Brigham and Women’s Center for Clinical Investigation. They had no access to windows, watches, or electronics that would clue their body clocks into the time. The effect of circadian misalignment could be determined by comparing how their body functions changed from before to after simulated night work.
Study participants followed a “constant routine protocol,” a controlled laboratory setup that can tease apart the effects of circadian rhythms from those of the environment and behaviors (e.g., sleep/wake, light/dark patterns). During this protocol, participants stayed awake for 32 hours in a dimly lit environment, maintaining constant body posture and eating identical snacks every hour. After that, they participated in simulated night work and were assigned to either eating during the nighttime (as most night workers do) or only during the daytime. Finally, participants followed another constant routine protocol to test the aftereffects of the simulated night work. Importantly, both groups had an identical schedule of naps, and, thus, any differences between the groups were not due to differences in sleep schedule.
The investigators examined the aftereffects of the food timing on participants’ cardiovascular risk factors and how these changed after the simulated night work. Researchers measured various cardiovascular risk factors, including autonomic nervous system markers, plasminogen activator inhibitor-1 (which increases the risk of blood clots), and blood pressure.
Remarkably, these cardiovascular risk factors increased after simulated night work compared to the baseline in the participants who were scheduled to eat during the day and night. However, the risk factors stayed the same in the study participants who only ate during the daytime, even though how much and what they ate was not different between the groups—only when they ate.
Limitations of the study include that the sample size was small, although of a typical size for such highly controlled and intensive randomized controlled trials. Moreover, because the study lasted two weeks, it may not reflect the chronic risks of nighttime versus daytime eating.
A strength is that the study participants’ sleep, eating, light exposure, body posture, and activity schedule were so tightly controlled.
“Our study controlled for every factor that you could imagine that could affect the results, so we can say that it’s the food timing effect that is driving these changes in the cardiovascular risk factors,” said Sarah Chellappa, MD, MPH, PhD, an associate professor at the University of Southampton, and lead author for the paper.
While further research is necessary to show the long-term health effects of daytime versus nighttime eating, Scheer and Chellappa said the results are “promising” and suggest that people could improve their health by adjusting food timing. They add that avoiding or limiting eating during nighttime hours may benefit night workers, those who experience insomnia or sleep-wake disorders, individuals with variable sleep/wake cycles, and people who travel frequently across time zones.
In addition to Scheer, Mass General Brigham authors include Lei Gao, Jingyi Qian, Nina Vujovic, Peng Li, and Kun Hu.
NewsMakers
Women non-smokers around 50% more likely than men to develop COPD
Smoking is the principal cause of COPD. But despite significant falls in cigarette smoking over the past 50 years, it remains a leading cause of death, with the prevalence of COPD in women approaching that of men, say the researchers.

Women’ are around 50% more likely than men to develop COPD, the umbrella term for chronic lung conditions, such as emphysema and bronchitis, even if they have never smoked or smoked much less than their male counterparts, suggests observational research, published in the open access journal BMJ Open Respiratory Research.
The findings challenge the widely held belief that women’s increased vulnerability to cigarette smoke likely explains this disparity, conclude the researchers.
Smoking is the principal cause of COPD. But despite significant falls in cigarette smoking over the past 50 years, it remains a leading cause of death, with the prevalence of COPD in women approaching that of men, say the researchers.
Women with COPD tend to have more severe symptoms, and at a younger age, than their male counterparts, prompting the suggestion that the explanation may lie in a heightened susceptibility to the effects of cigarette smoke, explain the researchers.
To clarify the associations between gender, cigarette smoke, and COPD, and to update previous estimates of the prevalence and impact of COPD, the researchers drew on a large nationally representative US survey of adults from the 2020 National Health Interview Survey (NHIS).
Respondents (12,638 women and 10,390 men aged at least 40) were asked about their smoking history, what tobacco products they used, and whether they vaped.
Women reported lower rates of both current and former cigarette, cigar, and pipe smoking, and smokeless tobacco use than men, but similar rates of vaping.
The prevalence of COPD was just under 8% for women and 6.5% for men. Women with COPD were more likely to have never smoked cigarettes than men with COPD (26.5% vs just over 14%), and less likely to use other tobacco products except for e-cigarettes (26.5% vs 20%).
Women also reported smoking fewer daily cigarettes than men, averaging around 18 compared with around 22, and to have done so for fewer years. And they were less likely than men to have started smoking before the age of 15:19% vs 28%.
Yet the prevalence of COPD was higher among women who had ever smoked than it was among men: 16% vs 11.5%. And among women who had never smoked the prevalence of COPD was almost twice as high as it was in male non-smokers: just over 3% compared with just over 1.5%.
In further analysis, female gender was associated with a significantly (47%) higher risk of being diagnosed with COPD after accounting for potentially influential factors.
This gender difference in risk persisted, irrespective of smoking history: among those who had never smoked, women were 62% more likely to be diagnosed with COPD, and among those who had ever smoked they were 43% more likely to do so.
The researchers acknowledge that their study relied on self report rather than objectively measured data. And they lacked potentially important information on hormonal influences, family history, or infectious, occupational, and environmental exposures.
But they nevertheless suggest: “These findings should raise questions about whether differing susceptibility to tobacco smoke is the key factor driving the increased COPD prevalence in women in the USA.
“If women were more susceptible to the effects of smoking, we would not expect to see a nearly identical risk per 10 pack-year exposure, nor would we expect to see a similarly increased relative risk among those who had never smoked.”
And they conclude: “Our findings refine prior estimates of COPD among those without a smoking history and re-emphasise the high burden of COPD in women, underscoring the need for thoughtful efforts to prevent, diagnose, and treat their disease.”
NewsMakers
Research suggests drinking coffee may reduce the risk of frailty
Habitual coffee consumption of 4-6 cups and over* (with one cup measuring at 125ml) per day is associated with a reduced risk of frailty.

A new study published in the European Journal of Nutrition has suggested that habitual coffee consumption of 4-6 cups and over* (with one cup measuring at 125ml) per day is associated with a reduced risk of frailty.
The study, funded by the Institute for Scientific Information on Coffee (ISIC) is the first to analyze the relationship between coffee consumption and the underlying components of frailty.
Coffee consumption has previously been linked to reducing the risk of some of the natural symptoms of ageing, such as improving cognitive function2 and mitigating against inflammatory related diseases. This latest research adds to the growing knowledge base within this area, exploring the benefits of regular coffee consumption over an extended period of time.
For this study, researchers conducted a detailed analysis over a long seven-year follow-up period, surveying 1,161 adults aged 55+ years through the Longitudinal Aging Study Amsterdam (LASA).
The relationship between coffee consumption and the presence and incidence of frailty was investigated. Frailty status was evaluated using Fried’s five-component frailty phenotype4,which is defined by the presence of three or more of the following symptoms: weight loss, weakness, exhaustion, slow gait (walking) speed, and low physical activity.
The results of this study indicate that higher habitual coffee consumption is associated with lower overall odds of frailty. These findings can be considered alongside the European Food Safety Authority’s (EFSA) scientific opinion that up to 400mg of caffeine (3-5 cups of coffee) per day is a moderate and safe amount5.
The researchers explain that coffee’s effect on reducing frailty can partly be attributed to the role of antioxidants in coffee, which may help to reduce inflammation, sarcopenia (muscle loss), and prevention of muscle damage. Coffee may also help to improve regulating insulin sensitivity and glucose uptake in older people.
The study’s lead author, Margreet R. Olthof, Associate Professor at the Amsterdam Public Health Research Institute, Vrije Universiteit Amsterdam, commented: “Drinking coffee is a key part of many people’s daily routine, and as people age they are constantly looking for ways to maintain their health. Our findings highlight the possible beneficial association between daily coffee consumption and reduced risk of frailty in later life in the older population. Coffee consumption may thus enhance healthy aging, but it is important we also explore further dietary interventions, to ensure older adults can continue to live fulfilling lives.”
* Moderate coffee consumption can be defined as 3–5 cups per day, based on the European Food Safety Authority’s review of caffeine safety.
NewsMakers
Landers opens first Cavite store in Vermosa
Landers Superstore, the fastest growing membership store in the country, proudly marks another milestone with the grand opening of Landers Vermosa – its first-ever store in the province and its 15th store nationwide.

Premium membership shopping has finally arrived in Cavite.
Landers Superstore, the fastest growing membership store in the country, proudly marks another milestone with the grand opening of Landers Vermosa – its first-ever store in the province and its 15th store nationwide.
Conveniently located inside Ayala Vermosa’s sprawling estate and lifestyle hub in Imus, Cavite, the newest Landers store offers a fresh and elevated way of shopping for Caviteños, complete with massive savings, world-class finds, and exclusive membership perks, all under one roof. It is also the largest Landers store to date at 12,900 sqm, promising a bigger and better experience for every member who walks through its doors.
Welcoming Landers in Cavite
Landers Vermosa opened with an exciting grand launch that brought together members of the media, content creators, and special guests for a first look at the newest and biggest Landers Superstore. The attendees were in high spirits as they explored the spacious store and enjoyed exclusive product samplings and guided tours.
During the event, Landers Deputy Chief Executive Officer Bill Cummings delivered heartfelt opening remarks, expressing his excitement for the new store and his appreciation for the warm welcome from the Cavite community, noting that over 60,000 members had already signed up prior to opening day – a clear sign of the anticipation surrounding the launch.
The celebration also highlighted the strong collaboration between Landers Superstore and Ayala Land, along with the support of the city government of Imus, led by Mayor Alex Advincula. The event underscored Landers’ commitment to bringing world-class shopping experiences to more Filipino families, starting with the vibrant and growing community in Cavite.
What to expect at Landers Vermosa
At Landers Vermosa, members can look forward to filling their carts with high-quality local and imported products—from daily essentials to unique international finds. Beyond shopping, the store offers a host of exclusive perks that make every visit more rewarding. Members can enjoy free haircuts or blow-dry services at Federal Barbers, low-priced medicine and wellness products at Capital Care Pharmacy, up to P10 off per liter at Landers-Caltex gas stations, and up to 50% off on Solane LPG refills.
Members of Landers Vermosa will gain access to all of Landers Superstore’s massive sale events like Super Crazy Sale and 50% Off Produce Sale, which offer unbeatable savings on a wide range of products. To complete the experience, members can enjoy regular in-store activities every month and free product samplings that are perfect for the whole family.
Sign up for Landers membership
Be among the first to explore this exciting new shopping destination and enjoy all the perks that come with being a Landers member.
If you’re not yet a member, now’s the perfect time to sign up! Memberships are currently on sale at 50% off—just P350 for a full year of exclusive savings and benefits. Promo runs until May 31.
Looking for even more value? Apply for the Landers Cashback Everywhere Credit Card and get up to 5% cashback on all Landers purchases, plus earn rewards wherever you shop.
Landers Vermosa is here with more perks, more savings, and more reasons to love shopping in the South. See you in-store.
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