NewsMakers
Children exposed to tobacco smoke at home have worse heart function as adults
Recognizing that adult cardiovascular health is influenced by factors across the lifespan including childhood may be important in advocacy initiatives and in implementing interventions to reduce the risks. These could include messages and programs that can help prompt parents to protect their children from tobacco smoke and the associated long-term health risks.
The more secondhand tobacco smoke children breathe at home while growing up, the higher chance they have of developing markers of decreased heart function as adults, according to research presented at the American Heart Association’s Scientific Sessions 2020.
“We already know from previous studies that children exposed to secondhand smoke are more likely to have structural differences in their vascular systems as adults, such as thicker blood vessel walls and a higher risk of plaque buildup in the arteries,” said Chigoze Ezegbe, M.B.B.S., M.P.H., lead author of the study and a Ph.D. candidate at the Menzies Institute for Medical Research at the University of Tasmania in Hobart, Australia. “In this study, we wanted to understand the impact of prolonged secondhand smoke exposure during childhood on heart function in adulthood.”
The investigators examined the health records of more than 1,100 adults (average age 45 years, 52% female) who are participants in the ongoing Childhood Determinants of Adult Health study, an Australia-wide research project initiated in 1985 that investigates the importance of childhood factors in the later development of risk factors for heart disease and stroke.
About half (54%) of the participants were exposed to secondhand smoking at home during childhood. The participants’ most recent evaluation was between 2014 and 2019, 34 years after they entered the study as schoolchildren.
The severity of childhood smoking exposure was calculated three ways: the number of smokers in the home; the number of years each child was exposed to tobacco smoking by household members; and the severity of exposure index – whether a child was said to be exposed in the home never, sometimes or always.
In the adult evaluation, ultrasound imaging was used to measure the global longitudinal strain (GLS) of the left ventricle, the heart’s major pumping chamber. GLS indicates how much the muscles of the left ventricle shorten as they help squeeze blood out of the heart, compared with the muscles’ resting length between heartbeats.
“The GLS can show early changes in the ability of the heart to contract properly and that can provide information on the risk of heart disease,” Ezegbe said. “Previous research shows that each 1% decrease in GLS has been associated with a 12% higher risk of cardiovascular morbidity and mortality in a low-risk, general population.”
Researchers found that adult global longitudinal strain declined significantly:
- With each additional member of the child’s household who smoked, which ranged from 0-5 smokers;
- With more years of childhood exposure to tobacco smoke; and
- With higher scores on the childhood severity of exposure index.
“These findings extend our previous work on the structure of the vascular system to suggest that how the heart functions is also affected when exposed to passive smoke,” said Seana Gall, Ph.D., senior author of the study and associate professor of cardiovascular and respiratory health and disease at the Menzies Institute for Medical Research at the University of Tasmania.
The researchers are currently examining other cardiovascular effects of secondhand smoke exposure, including alterations in blood pressure and plaque buildup in arteries.
“Recognizing that adult cardiovascular health is influenced by factors across the lifespan including childhood may be important in advocacy initiatives and in implementing interventions to reduce the risks. These could include messages and programs that can help prompt parents to protect their children from tobacco smoke and the associated long-term health risks,” Ezegbe said.
The study is limited by not having information on participants’ prenatal exposure to smoking or on the number of cigarettes smoked around them. This information would have been valuable to determine if there was any dose-response effect to secondhand smoke.
“Children, especially young children, are typically exposed to tobacco smoke involuntarily, with little choice, yet it clearly can affect their health,” said Rose Marie Robertson, M.D., FAHA, deputy chief science and medical officer of the American Heart Association and co-director of the Association’s Tobacco Center of Regulatory Science. “This study confirms that children should be protected from passive smoking — because it negatively impacts their health during childhood, and it leads to long-term health consequences in adulthood.”
These findings from Australia should be generalizable to any United States population with a high level of childhood exposure to secondhand smoke, according to the researchers.
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Co-authors are Costan G. Magnussen, Ph.D.; Amanda L. Neil, Ph.D.; Marie-Jeanne Buscot, Ph.D., M.Sc.; Tom Marwick, M.B.B.S., Ph.D., M.P.H.; Terence Dwyer, M.B.B.S., M.D., M.P.H.; and Alison Venn, Ph.D. Author disclosures are in the abstract. The National Health and Medical Research Council of Australia funded the study.
Beauty & Fashion
Redefining aesthetics: From anti-aging to healthy aging
Growing attention is now being given to healthy aging, understanding how the entire face changes over time, preserving facial harmony, and helping people continue to look like themselves.
For decades, “anti-aging” has defined the beauty and aesthetics conversation, promising to erase wrinkles and reverse the signs of time. Today, that conversation is shifting.
Aging is no longer just about looking younger. Growing attention is now being given to healthy aging, understanding how the entire face changes over time, preserving facial harmony, and helping people continue to look like themselves.
A review published in Facial Plastic Surgery, The Anatomy of the Aging Face: A Review, describes aging as changes across bone, ligaments, muscles, fat, and skin. Another review in Aesthetic Surgery Journal, The Facial Aging Process From the “Inside Out”, explains how changes beneath the surface eventually become visible on top.
Studies in Plastic and Reconstructive Surgery show facial fat is organized into distinct anatomical compartments that can lose volume and shift position over time, altering facial shape and balance.
For multi-awarded aesthetic physician Dr. James Co, founder of Cosma Institute and Architect of Aesthetic Confidence, these findings are the reason aesthetic care must start with understanding, not just treating.
“Aging is not a disease we need to cure,” Co said. “It is a biological process. As physicians, our role is to understand what is changing beneath the surface, how those changes differ from person to person, and whether intervention is appropriate in the first place.”
“When you only look at the wrinkle, you are looking at the surface of a much bigger anatomical process,” he added. “The face ages as a system. Good assessment means understanding what is happening underneath before deciding what should be done on the surface.”
Part of that understanding is recognizing that no two faces age the same way. Two people can be the same age and experience aging very differently. Genetics, skeletal structure, fat distribution, skin characteristics, sun exposure, lifestyle, and environmental factors all influence how aging presents.
“Two patients can be the same age and come to me with completely different anatomy, lifestyles, concerns, and goals,” Co said. “Why would we expect their treatment plans to look exactly the same?”
This is where healthy aging broadens the conversation — from fixing isolated signs to looking at the face as a whole and listening to what the individual actually wants.
“Someone can want to look refreshed without wanting to look 20 years younger,” Co said. “Those are completely different goals.”
Rather than trying to freeze one version of the face forever, healthy aging acknowledges that the face will continue to change. As different structures change at different rates, the relationship between features evolves. Facial harmony is therefore not fixed.
“You cannot freeze one version of your face forever,” Co said. “But you can understand how the face is changing and make decisions that respect its natural proportions and your identity.”
In the age of social media, where aesthetic treatments are highly visible, Co cautions against self-diagnosis.
“Patients should not have to diagnose themselves from social media,” he said. “You might recognize a concern, but deciding why it is happening and what should be done about it requires proper assessment.”
The shift is also about how people feel, not just how they look. A 2022 review on minimally invasive facial aesthetic procedures found studies are increasingly looking beyond physical changes to include satisfaction with appearance and aspects of psychological and social well-being, while noting that evidence still needs careful interpretation.
For Co, this reinforces that success is not always about looking dramatically younger.
“We need to ask whether the result makes sense for the patient, whether expectations were met, and whether we preserved the things that make that person recognizable,” he said. “I would rather someone tell my patient, ‘You look well,’ than immediately ask, ‘What did you have done?'”
At Cosma Institute, Co applies this consultation-led philosophy through individualized assessment, facial harmony, medical judgment, and patient education. Having trained aesthetic practitioners across Southeast Asia and Europe, he advocates for natural-looking outcomes that respect the characteristics already present in each face — an approach that recently earned him two awards at the Merz Aesthetics Tala Awards.
For Co, the evolution of aesthetic medicine is not about having more tools, but knowing when to use them — and when not to.
“Aging cannot be stopped, and I don’t think that should be the promise,” he said. “What we can do is understand it better. We can look at the science, understand the anatomy, listen to the patient, and make decisions that allow them to age while still looking recognizably like themselves.”
For Co, healthy aging begins not with fighting age, but with understanding it.
NewsMakers
The look and feel of your neighborhood may affect your sleep
Those living in neighborhoods rated as having a stronger sense of safety tended to sleep longer, and that this rating appeared to be shaped by the streetscape.
Your neighborhood’s “streetscape”—the physical environment of your street—is something that you have probably never consciously thought about, despite seeing it every day. But what if the streetscape was affecting you on a subconscious level and disrupting your sleep?
This intriguing question is posed by the findings of a study led by Professor Daisuke Matsushita of the Graduate School of Human Life and Ecology at Osaka Metropolitan University. The research team used AI to analyze more than 200,000 Google Street View images to identify visual neighborhood characteristics. They then linked these characteristics to the self-reported sleep of 1,089 working adults living on the lower floors of apartments in Tokyo, who were most likely to be affected by the streetscape.
They found that those living in neighborhoods rated as having a stronger sense of safety tended to sleep longer, and that this rating appeared to be shaped by the streetscape. Generally, people slept longer in areas with lots of greenery, such as leafy trees, on the street. Similarly, high “enclosure”—meaning many tall vertical buildings and few wide-open spaces—was also associated with longer sleep and fewer insomnia symptoms.
However, the study also made a surprising finding. The researchers found that highly walkable streetscapes, such as those with more sidewalks and traffic signs, were associated with a lowered sense of safety and shortened sleep duration.
This suggests that walkability does not always represent a reassuring environment. Instead, a possible explanation is that streets with extensive pedestrian infrastructure are often busier, more crowded, and used by more strangers, which may be perceived as less safe or less relaxing than quieter residential streets.
“This study demonstrates the potential for evaluating streetscape characteristics across large geographic areas in a cost-effective manner,” Dr. Matsushita said. “Based on the technique used in this study, cities could potentially measure perceived safety, beauty, liveliness, and enclosure as well as pollution and noise.”
“We hope that opening up this new perspective creates further possibilities for designing healthier neighborhoods,” he concludes.
The findings were published in Building and Environment.
NewsMakers
Workout or nap? Either can help your sleepless brain, study finds
People who either completed 20 minutes of moderate-to-vigorous exercise or took a 90-minute nap performed about 22 per cent better on memory tests after 30 hours without sleep than those who did neither.
A short workout or a nap can help protect memory after a sleepless night, a McGill University-led study has found.
Researchers found people who either completed 20 minutes of moderate-to-vigorous exercise or took a 90-minute nap performed about 22 per cent better on memory tests after 30 hours without sleep than those who did neither. The findings, published in Proceedings of the National Academy of Sciences (PNAS), point to practical ways to counter the effects of sleep deprivation.
“Sleep loss affects nearly every aspect of how we think and function, but many people can’t simply stop what they’re doing and get more sleep,” said senior author Marc Roig, Professor in McGill’s School of Physical and Occupational Therapy. “Our findings show that even a brief bout of exercise may help preserve one of our most important cognitive abilities.”
The study involved 54 healthy young adults who stayed awake for 30 consecutive hours under lab supervision. Participants were then assigned to one of three groups: a 20-minute cycling session, a 90-minute nap or a control condition. Three days later, researchers tested their memory for images they had viewed immediately after the intervention. Those who exercised or napped remembered significantly more images than participants who did neither.
Same result, different pathways
While the memory benefits were nearly identical, brain recordings revealed that exercise and napping helped in different ways.
Napping appeared to help the brain recharge, making it easier to take in and remember new information. Exercise, by contrast, helped the brain use its remaining resources more efficiently, without making participants feel more tired.
The findings could eventually inform fatigue-management strategies in workplaces where sleep loss is common and mistakes can have serious consequences, such as health care, transportation and emergency response.
“A nap isn’t always possible in the middle of a shift,” said first author Madhura Lotlikar, a doctoral candidate in McGill’s Department of Neurology and Neurosurgery. “Exercise is accessible, inexpensive and easy to implement. That makes it a promising tool to help people stay cognitively sharp when sleep is limited.”
The researchers emphasize that exercise cannot replace sleep, but it may help people function better when getting enough rest isn’t possible.
About the study
“Protecting episodic memory after sleep loss: Similar benefits of exercise and naps via distinct neural contributions” by Madhura Lotlikar and Marc Roig et al., was published in Proceedings of the National Academy of Sciences of the United States of America.
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