{"id":8660,"date":"2023-09-11T21:34:34","date_gmt":"2023-09-11T13:34:34","guid":{"rendered":"http:\/\/zestmag.com\/online\/?p=8660"},"modified":"2023-09-11T21:35:27","modified_gmt":"2023-09-11T13:35:27","slug":"synchronizing-your-internal-clocks-may-help-mitigate-jet-lag-effects-of-aging","status":"publish","type":"post","link":"https:\/\/zestmag.com\/online\/synchronizing-your-internal-clocks-may-help-mitigate-jet-lag-effects-of-aging\/","title":{"rendered":"Synchronizing your internal clocks may help mitigate jet lag, effects of aging"},"content":{"rendered":"\n

Traveling to faraway places is a great way to seek out new experiences, but jet lag can be an unpleasant side effect. Adjusting to a new time zone is often accompanied by fatigue, difficulty sleeping, and a host of other problems that can turn an otherwise exciting adventure into a miserable trip.<\/strong><\/p>\n\n\n\n

Jet lag is caused by a difference between the circadian system \u2014 the body\u2019s internal clock \u2014 and the surrounding environment. Around the turn of the century, scientists began to recognize that the body has multiple internal clocks, calibrated in different ways, and that jet lag-like symptoms can result when these clocks drift out of sync with each other. This can happen in several ways and grows more prevalent with age.<\/p><\/blockquote>\n\n\n\n

In Chaos<\/a><\/em>, from AIP Publishing, a team of scientists from Northwestern University and the Santa Fe Institute developed a theoretical model to study the interactions between multiple internal clocks under the effects of aging and disruptions like jet lag.<\/p>\n\n\n\n

Modern research has shown that circadian clocks are present in almost every cell and tissue in the body. Each relies on its own set of cues to calibrate; the brain\u2019s clock depends on sunlight, for instance, while the peripheral organs calibrate at mealtime.<\/p>\n\n\n\n

\u201cConflicting signals, such as warm weather during a short photoperiod or nighttime eating \u2014 eating when your brain is about to rest \u2014 can confuse internal clocks and cause desynchrony,\u201d said author Yitong Huang.<\/p><\/blockquote>\n\n\n\n

At this point, little is known about how the body\u2019s various internal clocks affect each other. The added complexity of accounting for multiple clocks means researchers tend to use simplified models.<\/p>\n\n\n\n

\u201cMost studies primarily focus on one particular time cue or a single clock,\u201d said Huang. \u201cImportant gaps remain in our understanding of the synchronization of multiple clocks under conflicting time cues.\u201d<\/p>\n\n\n\n

Huang and her colleagues took a different approach, building a mathematical framework that accounts for this complex interplay between systems. Their model features two populations of coupled oscillators that mimic the natural rhythms of circadian cycles. Each oscillator influences the others while simultaneously adjusting based on unique external cues.<\/p>\n\n\n\n

Using this model, the team was able to explore how such a coupled system could be disrupted and what makes the effect worse. They found that common symptoms of aging, such as weaker signals between circadian clocks and a lower sensitivity to light, result in a system that is more vulnerable to disruptions and slower to recover.<\/p>\n\n\n\n

They also landed on a new method to speed up recovery from jet lag and similar disruptions. According to their results, the way to better sleep is through the stomach.<\/p>\n\n\n\n

\u201cHaving a larger meal in the early morning of the new time zone can help overcome jet lag,\u201d says Huang. \u201cConstantly shifting meal schedules or having a meal at night is discouraged, as it can lead to misalignment between internal clocks.\u201d<\/p>\n\n\n\n

The article, “A minimal model of peripheral clocks reveals differential circadian re-entrainment in aging,” is authored by Yitong Huang, Yuanzhao Zhang, and Rosemary Braun. It appeared in Chaos<\/em>.<\/p>\n","protected":false},"excerpt":{"rendered":"

Having a larger meal in the early morning of the new time zone can help overcome jet lag. Constantly shifting meal schedules or having a meal at night is discouraged, as it can lead to misalignment between internal clocks.<\/p>\n","protected":false},"author":3,"featured_media":8661,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[7],"tags":[110,1077,845,1909,1564],"class_list":["post-8660","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-travel","tag-travel-2","tag-travel-destination","tag-travel-philippines","tag-travel-time","tag-travel-tips"],"_links":{"self":[{"href":"https:\/\/zestmag.com\/online\/wp-json\/wp\/v2\/posts\/8660","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zestmag.com\/online\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zestmag.com\/online\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zestmag.com\/online\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/zestmag.com\/online\/wp-json\/wp\/v2\/comments?post=8660"}],"version-history":[{"count":2,"href":"https:\/\/zestmag.com\/online\/wp-json\/wp\/v2\/posts\/8660\/revisions"}],"predecessor-version":[{"id":8663,"href":"https:\/\/zestmag.com\/online\/wp-json\/wp\/v2\/posts\/8660\/revisions\/8663"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/zestmag.com\/online\/wp-json\/wp\/v2\/media\/8661"}],"wp:attachment":[{"href":"https:\/\/zestmag.com\/online\/wp-json\/wp\/v2\/media?parent=8660"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zestmag.com\/online\/wp-json\/wp\/v2\/categories?post=8660"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zestmag.com\/online\/wp-json\/wp\/v2\/tags?post=8660"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}