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GSK’s Panadol relieves pain in 15 minutes

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At the Panadol launch, from left, Mr. Jeoffrey Yulo, General Manager, GSK Consumer Healthcare; Dr. Joy Luat-Inciong; and Ryan Agoncillo.

At the Panadol launch, from left, Mr. Jeoffrey Yulo, General Manager, GSK Consumer Healthcare; Dr. Joy Luat-Inciong; and Ryan Agoncillo.

Experiencing pain is not normal; in fact, it is the body’s way of saying “that something is not right and is in need of attention,” according to Dr. Joy Luat-Inciong of the Pain Society Philippines. Luat-Inciong recommends for people to heed to experienced pain, be it through exercise or taking of medicines, such as pain killers.

To provide a fast and effective solution to pain sufferers, GlaxoSmithKline has brought to the Philippines Panadol with Optizorb, a paracetamol based analgesic that provides fast, effective temporary relief of pain and discomfort associated with: headache, tension headache, period pain, cold and flu symptoms, migraine headache, muscular aches, arthritis/osteoarthritis, backache, and toothache.

Panadol also helps to reduce fever. It is also a good choice of pain reliever for people with sensitive stomachs, stomach ulcers and other stomach disorders. Panadol can also be used by breast feeding women, says GSK.

“Seven out of 10 Filipinos suffer from regular headaches. The time wasted on dealing with this kind of pain should have been better spent on more important things like quality time with the family,” says Jeoffrey Yulo, General Manager – Consumer Healthcare, GSK Philippines.

“What makes Panadol with Optizorb truly different from other branded and generic paracetamol products is that it is the only product to contain Optizorb, which has revolutionized the way paracetamol tablets are dispersed in the body, so it allows paracetamol to reach the bloodstream more quickly and be carried to where it acts to fight pain, five times faster.”

According to Luat-Inciong, it takes 40 to 45 minutes for standard Paracetamol to dissolve or break apart into smaller pieces called granules. It takes another 60 to 70 minutes for the granules to disintegrate or break into particles small enough to dissolve in the stomach. The particles are finally absorbed throughout the body and into the bloodstream – where the medicine can take effect, a process that can take 45 to 60 minutes.

“Panadol with Optizorb dissolves five times faster, disintegrates in 12.9 minutes and delivers pain relief in 15 minutes,” said Luat-Inciong.

Brand ambassador

This year, Panadol brings more focus to help take away the pain for faster recovery and more super moments with the ones you love. Bringing this life-affirming message to the fore is father/athlete/host Ryan Agoncillo, together with his son Lucho. Ryan is known to be a dedicated father to his children – Yohan and Lucho – and spends as much time as he can with his family.

As a sportsman who is into motorcycles and triathlons, Ryan is no stranger to aches and pain. But he doesn’t let any kind of discomfort like headache get in the way of a quality time with his equally energetic son, making their moments together pain-free. But whenever pain or headache strikes, he puts his trust on Panadol. And like a true superhero, he has the power of quick recovery in the eyes of his son.

“My family is my top priority. Even if I get busy with work and my other pursuits, I make sure that I get to spend quality with my wife and my kids. But, sometimes, because of my workload, I suffer from terrible headaches,” Ryan relates. “Fortunately, there’s Panadol. It offers fast relief to make my super moments with my family pain-free! Indeed, when pain is gone, life takes its place.”

Panadol with Optizorb comes in 36 x 10s dispenser box and a 10s pack. Each tablet has an SRP of PHP 4.00 and is available at all leading drugstores nationwide.

Other variants of Panadol coming

In a brief chat with ZestMag.com, Yulo revealed that GSK will be bringing other variants of Panadol to the country in the future. Panadol with Optizorb is known as Panadol Advance in other countries.

“[The pain relief market] is a big market. There are a lot of players; but with the different brands we have, we’re looking at a bigger pain market.”

Paracetamol should be used as directed in product information. The maximum dose within a 24-hour period must not be exceeded. However, if you find you need to use paracetamol on a regular basis, it is worth consulting your doctor to look at the cause, and possible treatments.– With notes from Mick Tan.

MELBA V. BERNAD started her career as an IT journalist with Computerworld Philippines which she joined in December 1993. She was Editor of the publication when she left in March 2013. Melba is currently Manila-based Editor of Networks Asia (Singapore), SMBWorld Asia (Singapore), and CFO Innovation Asia (Hong Kong). She is a two-time awardee of the Catholic Mass Media Awards (Best News Coverage in 2003 and Best News Coverage (Print) in 2004). She was also an awardee of the first Philippine Cyberpress Journalism Award. Melba is a co-publisher and concurrent Editor in Chief of Zest Magazine.

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Pru Life UK agents, customers, executives celebrate Year of the Wood Dragon

The insurer maintains its top position in New Business Annual Premium Equivalent & total Premium Income from Variable Life Insurance products according to the Insurance Commission’s Life Insurance Sector Quarterly Statistics for Q3 2023.

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With a strengthened commitment to providing better financial protection for every Filipino, Pru Life UK celebrates the start of the Year of the Wood Dragon. Over 200 Pru Life UK leaders, agents, clients, and employees joined and wished everyone PRU Love during the festivities held at the heart of its Escolta branch in Binondo Manila.

The insurer maintains its top position in New Business Annual Premium Equivalent & total Premium Income from Variable Life Insurance products according to the Insurance Commission’s Life Insurance Sector Quarterly Statistics for Q3 2023.

Pru Life UK’s products are made accessible through its over 42,000 digitally-empowered agency workforce and like-minded partners.

The Company recently launched PRULove for Life – an affordable, limited-pay, whole-life participating plan for as low as Php 87 per day* with lifetime coverage up to age 100 and flexible payment terms of 5, 10, 15, or 20 years to pay. To know more about PRULove for Life, talk to your Pru Life UK agent today or visit Pru Life UK’s website.

Pru Life UK is also committed to driving up financial awareness, literacy, and inclusion in the country by leading industry discussions and programs for the community. Its PRUBabies campaign seeks to protect 175,000 newborns with free insurance coverage against select infectious diseases such as Dengue, Typhoid, Measles, and Malaria.

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Eating too much protein is bad for your arteries, and this amino acid is to blame

Consuming over 22% of dietary calories from protein can lead to increased activation of immune cells that play a role in atherosclerotic plaque formation, driving the disease risk.

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University of Pittsburgh School of Medicine researchers discovered a molecular mechanism by which excessive dietary protein could increase atherosclerosis risk. The findings were published in Nature Metabolism.

The study, which combined small human trials with experiments in mice and cells in a Petri dish, showed that consuming over 22% of dietary calories from protein can lead to increased activation of immune cells that play a role in atherosclerotic plaque formation, driving the disease risk. Furthermore, the scientists showed that one amino acid – leucine – seems to have a disproportionate role in driving the pathological pathways linked to atherosclerosis, or stiff, hardened arteries.

“Our study shows that dialing up your protein intake in pursuit of better metabolic health is not a panacea. You could be doing real damage to your arteries,” said senior and co-corresponding author Babak Razani, M.D., Ph.D., professor of cardiology at Pitt. “Our hope is that this research starts a conversation about ways of modifying diets in a precise manner that can influence body function at a molecular level and dampen disease risks.”

According to a survey of an average American diet over the last decade, Americans generally consume a lot of protein, mostly from animal sources. Further, nearly a quarter of the population receives over 22% of all daily calories from protein alone.

That trend is likely driven by the popular idea that dietary protein is essential to healthy living, says Razani. But his and other groups have shown that overreliance on protein may not be such a good thing for long-term health.

Following their 2020 research, in which Razani’s laboratory first showed that excess dietary protein increases atherosclerosis risk in mice, his next study in collaboration with Bettina Mittendorfer, Ph.D., a metabolism expert at the University of Missouri, Columbia, delved deeper into the potential mechanism and its relevance to the human body.

To arrive at the answer, Razani’s laboratory, led by first-authors Xiangyu Zhang, Ph.D., and Divya Kapoor, M.D., teamed up with Mittendorfer’s group to combine their expertise in cellular biology and metabolism and perform a series of experiments across various models – from cells to mice to humans.

“We have shown in our mechanistic studies that amino acids, which are really the building blocks of the protein, can trigger disease through specific signaling mechanisms and then also alter the metabolism of these cells,” Mittendorfer said. “For instance, small immune cells in the vasculature called macrophages can trigger the development of atherosclerosis.”

Based on initial experiments in healthy human subjects to determine the timeline of immune cell activation following ingestion of protein-enriched meals, the researchers simulated similar conditions in mice and in human macrophages, immune cells that are shown to be particularly sensitive to amino acids derived from protein.

Their work showed that consuming more than 22% of daily dietary calories through protein can negatively affect macrophages that are responsible for clearing out cellular debris, leading to the accumulation of a “graveyard” of those cells inside the vessel walls and worsening of atherosclerotic plaques overtime. Interestingly, the analysis of circulating amino acids showed that leucine – an amino acid enriched in animal-derived foods like beef, eggs and milk – is primarily responsible for abnormal macrophage activation and atherosclerosis risk, suggesting a potential avenue for further research on personalized diet modification, or “precision nutrition.”

Razani is careful to note that many questions remain to be answered, mainly: What happens when a person consumes between 15% of daily calories from protein as recommended by the USDA and 22% of daily calories from protein, and if there is a ‘sweet spot’ for maximizing the benefits of protein – such as muscle gain – while avoiding kick-starting a molecular cascade of damaging events leading to cardiovascular disease.

The findings are particularly relevant in hospital settings, where nutritionists often recommend protein-rich foods for the sickest patients to preserve muscle mass and strength.

“Perhaps blindly increasing protein load is wrong,” Razani said. “Instead, it’s important to look at the diet as a whole and suggest balanced meals that won’t inadvertently exacerbate cardiovascular conditions, especially in people at risk of heart disease and vessel disorders.”

Razani also notes that these findings suggest differences in leucine levels between diets enriched in plant and animal protein might explain the differences in their effect on cardiovascular and metabolic health. “The potential for this type of mechanistic research to inform future dietary guidelines is quite exciting,” he said.

Additional authors of the study are Yu-Sheng Yeh, Ph.D., also from Pitt; Alan Fappi, Ph.D. and Vasavi Shabrish, Ph.D., both of the University of Missouri, Columbia; Se-Jin Jeong, Ph.D., Jeremiah Stitham, M.D., Ph.D., Ismail Sergin, Ph.D., Eman Yousif, M.D., Astrid Rodriguez-Velez, Ph.D., Arick Park, M.D., Ph.D., Joel Schilling, M.D., Ph.D., Marco Sardiello, Ph.D., Abhinav Diwan, M.D., Nathan Stitziel, M.D., Ph.D., Ali Javaheri, M.D., Ph.D., Irfan Lodhi, Ph.D., and Jaehyung Cho, Ph.D., all of Washington University School of Medicine, St. Louis; Arif Yurdagul Jr, Ph.D., and Oren Rom, Ph.D., both of the Louisiana State University Health Sciences Center; and Slava Epelman, M.D., Ph.D., of the University of Toronto.

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IRONKIDS Cebu in Lapu-Lapu partners with RLC Residences

This April will be the first event of the partnership as the brand extends their support for the budding young athletes. The aquathlon will see participants from ages 6 to 15 years old complete the race happening at The Reef Island Resort in Mactan.

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The IRONMAN Group Philippines and RLC Residences have announced in 2023 a new partnership—as the residential brand of Robinsons Land Corporation, RLC Residences becomes the title sponsor for IRONKIDS Lapu-Lapu and IRONKIDS Davao for 2024.

This April will be the first event of the partnership as the brand extends their support for the budding young athletes.  The aquathlon will see participants from ages 6 to 15 years old complete the race happening at The Reef Island Resort in Mactan.

RLC Residences Head of Brand Management Mr. Dan Carlo Torres shares his enthusiasm towards the event. “We are very excited to see this partnership unfold. We’ve been very supportive of IRONMAN, especially IRONKIDS because we also believe in the importance of promoting an active and purposeful lifestyle at such a young age and we hope to continuously be part of IRONMAN as we create more vibrant opportunities for our future triathletes,” he added.

“As we aspire to live our best lives, we work to inspire the wider community,” said Ms Princess Galura, Regional Director of the IRONMAN Group Philippines.  “For 10 years, the IRONKIDS has been a part of the Cebuano youth’s stepping stone to either a future in sports, representing the Philippines in international events, as well as planting the seeds of a healthy, sporty lifestyle.  Our partnership with RLC Residences allows us to do so and we are excited to hold the festivities for our youth once again in Lapu-Lapu this April,” she added.

The IRONKIDS event in Lapu-Lapu will feature age group categories for the 6 to 8 years old, 9 to 10 years old, 11 to 12 years old and 13 to 15 years old.  Relay categories are also available for mixed team relay for 6-10 year-olds and 11-15 year-olds. 

Swim and run courses, the transition area and finish line will be at The Reef Island Resort, which is conveniently located in a gated community.  Families who are checked in during race weekend can enjoy amenities of the resort –  including the beach, lap pool and game room.  The resort’s restaurant is operated by Cebu-based top tier chain, Abaca.

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