Pet Care
Boehringer Ingelheim launches its first-in-class broad-spectrum topical parasite treatment for cats
The new treatment is designed to safeguard cats from a wider range of parasites than any other product on the market, covering both external parasites and internal parasites such as fleas, ticks, ear mites, face mange, hookworm, roundworm, vesical worm, lungworm, heartworm prevention, as well as tapeworm infections that affect their health and quality of life.
Boehringer Ingelheim, a global leader in animal health, has launched the parasite treatment, NexGard COMBO for cats. With nearly 20 years of expertise in preventing parasites such as fleas, ticks, Lyme disease and more in dogs, NexGard now adds a feline-specific product to the NexGard family. The new treatment is designed to safeguard cats from a wider range of parasites than any other product on the market, covering both external parasites and internal parasites such as fleas, ticks, ear mites, face mange, hookworm, roundworm, vesical worm, lungworm, heartworm prevention, as well as tapeworm infections that affect their health and quality of life.
Parasite infections are common in cats and prevalent across Asia. According to an epidemiological study of over 1,000 cats in eastern and Southeast Asia, 43% of pet cats suffer from external parasites such as fleas, ticks and mites and 14% harbour deadly internal parasites such as hookworm, heartworm and roundworm.[i]
“Boehringer Ingelheim has always been on the cutting edge of research and development in the parasiticide space. Trusted by pet owners and veterinarians alike, our NexGard® family of products is currently ranked top in pet parasiticide sales worldwide. In Asia where over 26% of pet owners have cats[ii], we are thrilled to expand our feline parasite prevention line-up, which includes Broadline and FRONTLINE PLUS Cat, with NexGard COMBO for cats. It is an innovative one-and-done formula with esafoxolaner, the first isoxazoline parasiticide formulated for cats plus eprinomectin and praziquantel for the broadest external and internal parasite coverage to date,” said Sukje Sung, Head of Boehringer Ingelheim Animal Health Philippines, Inc.
Common misconceptions about parasites in cats
Parasite infections are often disregarded as trivial issues but can cause serious health complications in cats such as bloody diarrhoea, dehydration, skin inflammation and anaemia. Ear mites are common causes of feline ear infections which are often picked up when roaming outdoors and can cause itchiness, inflammation and swelling of the ear canal.3 Additionally, some internal parasites such as hookworms can attach themselves to the intestines and to feed on the blood of cats. Left untreated, hookworm infections can result in potentially life-threatening blood loss, weakness, and malnutrition.4
Despite the high prevalence of parasite infections, many pet owners remain unaware of how common they are. In fact, according to veterinary specialist Dr. Ross Antonio Banayo, Technical Manager for the Companion Animal Business Segment of Boehringer Ingelheim Animal Health Philippines, Inc. pet owners remain misinformed about how these parasites are transmitted and impact their cats. These common misconceptions include:
- Cats that are kept indoors are not susceptible to parasite infections and do not require regular veterinary visits.
- Cats only require treatment when they are infected with parasites. Preventive treatment is not necessary.
- Parasite infections are self-limiting and do not cause serious health issues.
- Removal of ticks and fleas can be effectively managed with parasite prevention shampoos alone.
According to Dr. Ross Antonio Banayo, Technical Manager for the Companion Animal Business Segment of Boehringer Ingelheim Animal Health Philippines, Inc. “Parasite infections can be particularly dangerous for cats. Common feline behaviours like grooming and roaming outdoors put them at a higher risk of contracting a variety of parasites. Often, cats only present with symptoms much later into the infection, resulting in worse complications. This highlights the need for us to change perceptions and move towards a preventive approach to parasite infections to safeguard their health.”
Parasites can be transmitted and affect human health too
Parasite infections not only impact the health of cats but can be transmitted to humans to cause complications such as skin infections, anaemia, gastrointestinal disturbances and more. Fortunately, transmission can be effectively prevented by administering regular parasiticide treatment for cats and adhering to regular follow-ups with a veterinarian.
“The lives of pets and humans are so deeply interconnected that their health issues can impact our own. Just as we are shifting towards a preventive approach to human health, NexGard COMBO is our preventive solution to preserve the health of cats. It represents the next step that we are taking to improve the health of animals across the region and drive a positive impact on our own health into the future,” said Sung.
The monthly treatment protects pet cats and their households from the deadly, debilitating, and transmittable internal and external parasites.
Important Safety Information
NexGard COMBO is for topical use only in cats. The most frequently reported adverse reactions include vomiting, application site reactions, and anorexia. If ingested, hypersalivation may occur.
Avoid direct contact with application site for 4 hours or until visibly dry.
Esafoxolaner is a member of the isoxazoline class. This class has been associated with neurologic adverse reactions including tremors, ataxia, and seizures in cats with or without a history of seizures.
Use with caution in cats with a history of seizures or neurologic disorders.
The safety of NexGard COMBO has been tested and is approved in breeding, pregnant, or lactating queen (cats) in the Philippines. The safety of the product has not been established in breeding male cats.
NexGard COMBO is for use in cats 8 weeks of age and older, weighing 0.8 kg or more.
[i] Colella V, Nguyen VL, Tan DY, Lu N, Fang F, Zhijuan Y, et al. Zoonotic Vectorborne Pathogens and Ectoparasites of Dogs and Cats in Eastern and Southeast Asia. Emerg Infect Dis. 2020;26(6):1221-1233. https://doi.org/10.3201/eid2606.191832. Accessed April 2023.
[i] Rakuten Insight. Pet Ownership in Asia. Available from https://insight.rakuten.com/pet-ownership-in-asia/. Accessed April 2023.
3 Little, S., and K. Duncan. “Ear mites: Uncovering, treating, and preventing infestations.” Today’s Veterinary Practice, 16 June 2021, todaysveterinarypractice.com/parasitology/ear-mites-uncovering-treating-and-preventing-infestations/. Accessed 9 May 2023
4 American Veterinary Medical Association. Parasites in cats and dogs. Available from https://ebusiness.avma.org/files/productdownloads/LR_COM_ClientBroch_InternalParasites.pdf Accessed May 2023.
Pet Care
Living with cats does not worsen asthma in children, suggests study
Children living with a cat had similar asthma severity, exacerbation, asthma control, and lung function to children living without cats in the short term.
Asthma is the most common chronic disease and one of the main causes of hospitalization among children. The Global Asthma Network has estimated that its global prevalence is 9.1% for children and 11.0% for adolescents, but this percentage varies greatly between countries, regions, and environments. Worldwide, the highest prevalence of pediatric asthma (above 20%) occurs in the British Isles and in parts of Oceania and the Middle East. Known risk factors for developing asthma include exposure to air pollution and smoking, childhood viral infections, obesity, and pre-existing allergies like eczema or hay fever.
Patients anecdotally self-report that exposure to animal dander appears to trigger asthma attacks. However, clinical and epidemiological data on this is so far contradictory, coming mostly from small studies on subgroups that aren’t necessarily representative of the wider population. Now, researchers have demonstrated in Frontiers in Allergy that sharing a home with cats may not worsen the outcomes of children with asthma and allergies.
“Here we show in a… cohort of children in Sweden with asthma and allergies, that children living with a cat had similar asthma severity, exacerbation, asthma control, and lung function to children living without cats in the short term,” said corresponding author Dr Resthie R Putri, a postdoctoral fellow at Karolinska Institutet in Stockholm.
“We also did not see any differences in asthma outcomes related to the number of cats, the cat’s sex, or the cat’s age.”
Large pediatric sample
In 2023, Putri and colleagues began a study on a cohort of 30,277 children – between four and 17 years old at the time – born between 2006 and 2020 and diagnosed with asthma or an airway allergy. They followed these over 24 months until 2024 to track asthma outcomes, drawing records on diagnoses, emergency visits, prescribed medications, and asthma control test and spirometry tests from linked data in the Swedish National Patient Register, Prescribed Drug Register, and National Airway Register.
In Sweden, registration in the National Cat Register has been mandatory since 2023 for all pet cats born after 2008. For each child, the authors noted whether the parental household had at least one cat in 2023, as was true for 9.4% of the children.
Cats don’t worsen asthma in kids
The results showed that there was no significant association between exposure to pet cats and asthma outcomes. For example, moderate-to-severe asthma – based on prescribed asthma medications – occurred in 9.6% of the cat-exposed children and 10.1% of the non-exposed children. Asthma ‘exacerbation’ (also known as an attack or flare-up) occurred in 3.3% of the cat-exposed children and 3.5% of the non-exposed children.
Among a subset of 1,428 children for whom asthma control and lung spirometry data were available, 97 (6.8%) lived with cats. There were no significant differences between the two groups in two common measures of lung function.
“One possible explanation is that cat allergen exposure is very common, even outside the home. Children who do not have cats at home may still be exposed in shared environments such as schools or public transportation, which could explain why we didn’t see a difference,” said Putri.
“While these large-scale findings provide valuable insight, we lacked data on which allergens the children were sensitized to, and because the National Cat Register is relatively new, some children living with cats may have been misclassified as unexposed,” she cautioned.
Pet Care
Tips to keep pets safe and happy no matter the season
The American Veterinary Medical Association (AVMA) is reminding everyone to keep pets safe no matter the season, and to think twice before gifting a pet as a surprise.
Special occasions can be a magical time, but they can also present hidden pet hazards and difficult decisions for pet owners and gift-givers. The American Veterinary Medical Association (AVMA) is reminding everyone to keep pets safe no matter the season, and to think twice before gifting a pet as a surprise.
“Holiday celebrations often mean delicious foods, beautiful decorations, and friends and family, which can be wonderful for us but may pose unexpected risks to our pets,” says Dr. Michael Q. Bailey, president of the AVMA. “The best gift you can give your pet… is the gift of good health and safety, which means keeping seasonal hazards out of reach, providing a quiet space away from the hustle and bustle, and ensuring emergency plans are in place in case the unexpected happens.”
Common hazards for pets include chocolate, baked goods (especially those containing the sugar substitute xylitol), table scraps, and certain seasonal plants like lilies, holly, and mistletoe. Tinsel, candles, electrical cords, and trees can also lead to injuries or worse if pets decide to investigate too closely.
Thinking about gifting a pet? Think again.
While the idea of a new puppy or kitten under the tree may warm hearts, the AVMA cautions against surprising someone with a live animal. Pets are long-term commitments that require a significant amount of time, planning, financial resources, and emotional investment.
“Bringing a pet into someone’s life is a decision that should never be made impulsively, and never without the foreknowledge of the recipient,” says Dr. Bailey. “Pets can bring immense joy, but they also require daily care, training, veterinary visits, and love for many years. A better option might be wrapping up a collar, toy, or gift certificate, and involving the future pet owner in choosing their new companion when the time is right.”
Instead of gifting a live animal, the AVMA recommends more thoughtful alternatives, such as:
- A leash or collar with a note promising a trip to a shelter or reputable breeder
- Books on pet care or breed characteristics
- A donation in the recipient’s name to a local animal shelter
Healthy gift ideas for pets
If your own pets are on your holiday list, the AVMA suggests practical and healthy gifts, such as:
- A veterinary wellness exam
- Toys that encourage exercise and mental stimulation
- Nutritional treats made for pets
- Updated parasite prevention
- Pet insurance
- A microchip (or updating existing chip info)
“Even something as simple as a microchip can be a lifesaving gift if your pet ever becomes lost,” adds Dr. Bailey. “It’s a gift that lasts a lifetime, and helps to ensure that you will be reunited if you and your pets become separated.”
For more holiday pet safety tips and resources, visit AVMA.org/holiday.
Pet Care
Plant-based dog foods are better for the environment than red meat options
Plant-based diets for pets had the lowest impact across all measures of environmental impact. This included the land needed to produce them, greenhouse gas emissions, the polluting effects of production on soil and water reservoirs, and freshwater withdrawal.
A study, led by experts at the University of Nottingham, has found that the production of meat-based pet foods has a much greater impact on the environment in comparison to plant-based alternatives.
The study, led by Rebecca Brociek from the School of Veterinary Medicine and Science, and published in Frontiers in Nutrition – Nutrition and Sustainable Diets, showed that plant-based diets for pets had the lowest impact across all measures of environmental impact. This included the land needed to produce them, greenhouse gas emissions, the polluting effects of production on soil and water reservoirs, and freshwater withdrawal.
Pet food production contributes substantially to global environmental issues, driven largely by animal-derived ingredients.
In this study, experts quantified the environmental impact of 31 commercially available dry dog foods purchased in the UK, categorised as plant-based, red-meat based and veterinary-renal diets.
The environmental metrics were estimated using life cycle assessment datasets and adjusted for ingredient makeup, energy density and differences in moisture content, which were mostly taken from the dog food packaging.
The results showed that plant-based diets had the lowest impact across all measures of environmental impact. Poultry-based and veterinary diets were intermediate, while beef and lamb-based foods had substantially higher impact compared to all other foods.
For example, over nine years of adult life, a 20kg dog fed a beef-based diet was estimated to require 57 football fields worth of land to grow their food (versus 1.4 fields for plant-based).
This latest study comes after a previous study where the team showed that plant-based pet food sold in the UK provided similar nutrition to meat-based food.
“Our findings show that there is a much greater environmental impact when producing meat-based pet food.
“We have already show in our previous work that plant-based diets at the point of purchase are roughly equivalent to others. This next paper is a case study of 31 supermarket-available dog foods, giving dog owners who factor sustainability into their purchases, guidance on how to also reduce their environmental pawprint,” says Rebecca, the lead author on the study.
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