Connect with us

Pet Care

Boehringer Ingelheim launches its first-in-class broad-spectrum topical parasite treatment for cats

The new treatment is designed to safeguard cats from a wider range of parasites than any other product on the market, covering both external parasites and internal parasites such as fleas, ticks, ear mites, face mange, hookworm, roundworm, vesical worm, lungworm, heartworm prevention, as well as tapeworm infections that affect their health and quality of life.

Published

on

Boehringer Ingelheim, a global leader in animal health, has launched the parasite treatment, NexGard COMBO for cats. With nearly 20 years of expertise in preventing parasites such as fleas, ticks, Lyme disease and more in dogs, NexGard now adds a feline-specific product to the NexGard family. The new treatment is designed to safeguard cats from a wider range of parasites than any other product on the market, covering both external parasites and internal parasites such as fleas, ticks, ear mites, face mange, hookworm, roundworm, vesical worm, lungworm, heartworm prevention, as well as tapeworm infections that affect their health and quality of life.

Parasite infections are common in cats and prevalent across Asia. According to an epidemiological study of over 1,000 cats in eastern and Southeast Asia, 43% of pet cats suffer from external parasites such as fleas, ticks and mites and 14% harbour deadly internal parasites such as hookworm, heartworm and roundworm.[i]

“Boehringer Ingelheim has always been on the cutting edge of research and development in the parasiticide space. Trusted by pet owners and veterinarians alike, our NexGard® family of products is currently ranked top in pet parasiticide sales worldwide. In Asia where over 26% of pet owners have cats[ii], we are thrilled to expand our feline parasite prevention line-up, which includes Broadline and FRONTLINE PLUS Cat, with NexGard COMBO for cats. It is an innovative one-and-done formula with esafoxolaner, the first isoxazoline parasiticide formulated for cats plus eprinomectin and praziquantel for the broadest external and internal parasite coverage to date,” said Sukje Sung, Head of Boehringer Ingelheim Animal Health Philippines, Inc.

Common misconceptions about parasites in cats

Parasite infections are often disregarded as trivial issues but can cause serious health complications in cats such as bloody diarrhoea, dehydration, skin inflammation and anaemia. Ear mites are common causes of feline ear infections which are often picked up when roaming outdoors and can cause itchiness, inflammation and swelling of the ear canal.3 Additionally, some internal parasites such as hookworms can attach themselves to the intestines and to feed on the blood of cats. Left untreated, hookworm infections can result in potentially life-threatening blood loss, weakness, and malnutrition.4

Despite the high prevalence of parasite infections, many pet owners remain unaware of how common they are. In fact, according to veterinary specialist Dr. Ross Antonio Banayo, Technical Manager for the Companion Animal Business Segment of Boehringer Ingelheim Animal Health Philippines, Inc. pet owners remain misinformed about how these parasites are transmitted and impact their cats. These common misconceptions include:

  • Cats that are kept indoors are not susceptible to parasite infections and do not require regular veterinary visits.
  • Cats only require treatment when they are infected with parasites. Preventive treatment is not necessary.
  • Parasite infections are self-limiting and do not cause serious health issues.
  • Removal of ticks and fleas can be effectively managed with parasite prevention shampoos alone.

According to Dr. Ross Antonio Banayo, Technical Manager for the Companion Animal Business Segment of Boehringer Ingelheim Animal Health Philippines, Inc. “Parasite infections can be particularly dangerous for cats. Common feline behaviours like grooming and roaming outdoors put them at a higher risk of contracting a variety of parasites. Often, cats only present with symptoms much later into the infection, resulting in worse complications. This highlights the need for us to change perceptions and move towards a preventive approach to parasite infections to safeguard their health.”

Parasites can be transmitted and affect human health too

Parasite infections not only impact the health of cats but can be transmitted to humans to cause complications such as skin infections, anaemia, gastrointestinal disturbances and more. Fortunately, transmission can be effectively prevented by administering regular parasiticide treatment for cats and adhering to regular follow-ups with a veterinarian.

“The lives of pets and humans are so deeply interconnected that their health issues can impact our own. Just as we are shifting towards a preventive approach to human health, NexGard COMBO is our preventive solution to preserve the health of cats. It represents the next step that we are taking to improve the health of animals across the region and drive a positive impact on our own health into the future,” said Sung.

The monthly treatment protects pet cats and their households from the deadly, debilitating, and transmittable internal and external parasites.

Important Safety Information

NexGard COMBO is for topical use only in cats. The most frequently reported adverse reactions include vomiting, application site reactions, and anorexia. If ingested, hypersalivation may occur.

Avoid direct contact with application site for 4 hours or until visibly dry.

Esafoxolaner is a member of the isoxazoline class. This class has been associated with neurologic adverse reactions including tremors, ataxia, and seizures in cats with or without a history of seizures.

Use with caution in cats with a history of seizures or neurologic disorders.

The safety of NexGard COMBO has been tested and is approved in breeding, pregnant, or lactating queen (cats) in the Philippines. The safety of the product has not been established in breeding male cats.

NexGard COMBO is for use in cats 8 weeks of age and older, weighing 0.8 kg or more.


[i] Colella V, Nguyen VL, Tan DY, Lu N, Fang F, Zhijuan Y, et al. Zoonotic Vectorborne Pathogens and Ectoparasites of Dogs and Cats in Eastern and Southeast Asia. Emerg Infect Dis. 2020;26(6):1221-1233. https://doi.org/10.3201/eid2606.191832. Accessed April 2023.

[i] Rakuten Insight. Pet Ownership in Asia. Available from https://insight.rakuten.com/pet-ownership-in-asia/. Accessed April 2023.

3 Little, S., and K. Duncan. “Ear mites: Uncovering, treating, and preventing infestations.” Today’s Veterinary Practice, 16 June 2021, todaysveterinarypractice.com/parasitology/ear-mites-uncovering-treating-and-preventing-infestations/. Accessed 9 May 2023

4 American Veterinary Medical Association. Parasites in cats and dogs. Available from https://ebusiness.avma.org/files/productdownloads/LR_COM_ClientBroch_InternalParasites.pdf Accessed May 2023.

Zest Magazine accepts contributions promoting everything about living the good life (and how to make this so). C'mon, give us a yell.

Pet Care

What happens when cats get fat? Scientists weigh in

As cats ate more and gained weight, gastrointestinal transit time was reduced, and so was digestive efficiency. When the body gets less food, it will be more efficient in extracting nutrients. But when the amount of food increases, it passes through the digestive system faster and fewer nutrients are extracted in the process

Published

on

Cat owners want Kitty to be happy, but providing an abundance of food and snacks can have unintended consequences. Feline obesity is on the rise, impacting the health, longevity, and wellbeing of cats. A new study from the University of Illinois Urbana-Champaign looks at what happens in the digestive system and gut microbiota when cats eat too much.

“About 60% of cats in the U.S. are overweight, which can lead to health problems such as diabetes and chronic inflammation. While many studies have investigated feline weight loss, there has been little focus on the opposite process, which is also important. In this study, we wanted to learn more about the metabolic and gastrointestinal changes that occur as a result of overeating and weight gain in cats,” says study co-author Kelly Swanson, professor in the Department of Animal Sciences and interim director of the Division of Nutritional Sciences (DNS), part of the College of Agricultural, Consumer and Environmental Sciences (ACES) at U. of I.

The study included 11 adult spayed female cats. They were fed a standard dry cat food and after two weeks of baseline measurements, they were allowed to eat as much as they wanted. The researchers collected blood and fecal samples at regular intervals and monitored physical activity.

Once the cats were able to overeat, they immediately increased their food intake substantially and started to gain weight. At the onset of the study, their average body condition score (BCS) was 5.41 on a 9-point scale. After 18 weeks of overfeeding, it had increased to 8.27, corresponding to being 30% overweight. BCS is equivalent to body mass index (BMI) for humans, and 6 or above is considered overweight, Swanson said.

The researchers analyzed changes in fecal output, gastrointestinal transit time, digestive efficiency (nutrient digestibility), and microbiota bacterial composition over the 20-week duration of the study.

“We found that as cats ate more and gained weight, gastrointestinal transit time was reduced, and so was digestive efficiency. When the body gets less food, it will be more efficient in extracting nutrients. But when the amount of food increases, it passes through the digestive system faster and fewer nutrients are extracted in the process,” Swanson explained.  

The researchers also found significant changes in gut microbial composition between the lean cats at baseline and after 18 weeks of weight gain. The relative abundance of Bifidobacterium, which has antimicrobial activity, inhibits pathogens, and stimulates the immune system, increased, while Collinsella, which degrades fiber and has been linked to pro-inflammatory diseases, decreased. These results are opposite to what has been measured in overweight humans and suggest that their association to weight gain is complex, Swanson noted.   

“The change in the gastrointestinal transit time was a novel finding and a potential reason for the change in fecal microbiota. Future studies should consider measuring transit time to better explain modifications to the microbiome of pets,” he added. 

As the cats’ food consumption grew, so did their fecal output. In other words, as they ate more, they also pooped more. At the same time, fecal pH decreased, meaning that the stool became more acidic.

“In humans, a low fecal pH indicates poor absorption of carbohydrates and fat. Our findings correlate with this, as reduced fecal pH aligned with higher food intake and reduced digestibility,” Swanson said.

The researchers also measured the cats’ activity level with a monitor attached to a collar. The cats were housed in a group setting where they were able to interact with each other and play with toys, except for the days when stool samples were collected.

“We expected that weight gain might lead to decreased physical activity, but we did not observe any consistent changes in activity level. However, this could vary with individual cats and their environment, and how much their owners interact with them,” Swanson stated.

Understanding the metabolic and gastrointestinal changes that occur with weight gain and obesity in pets may help with future prevention and treatment plans, the researchers conclude.

Pet owners who want to help their cats lose weight can employ various strategies. In another new study, Swanson and his co-authors showed that restricted feeding can promote safe weight and fat loss in cats. The researchers also suggest pet parents encourage activity in their feline companions. For example, they can stimulate foraging by placing food around the home, or use food puzzles during mealtime to promote engagement and mental enrichment.

After the conclusion of the weight gain study, the 11 cats were put on a restricted-feeding diet that helped them return to normal weight.

The first study, “Effects of overfeeding on the digestive efficiency, voluntary physical activity levels, and fecal characteristics and microbiota of adult cats,” is published in the Journal of Animal Science. Authors are Danielle Opetz, Patricia Oba, and Kelly Swanson.

Continue Reading

Pet Care

Fast facts about healthy skin and coat care for dogs

To get a better understanding of how you can improve your pet’s skin and coat, consider these facts and misperceptions.

Published

on

The condition and appearance of your dog’s skin and coat can serve as outward indicators of his or her overall health. While grooming is one of the most important steps to maintaining a healthy coat, other factors can play a role in the look and feel of your four-legged friend’s fur.

For example, dull, dry or flaky coats can be external indicators of internal issues. Stress, illness and inadequate nutrition can all lead to lackluster fur. Breed can also play a role in the shininess of your pet’s coat.

To get a better understanding of how you can improve your pet’s skin and coat, consider these facts and misperceptions from the experts at Petcurean, makers of the Go! Solutions line of premium pet food.

Fiction: Frequent washing dries out dogs’ skin and coats.

Regularly bathing your dog removes dirt, dander, debris and odors, and can help clear irritation-causing allergens. However, bathing too frequently removes natural oils, which keep skin supple and the coat soft and pliable. For best results, use a high-quality pet shampoo that’s gentle on the skin and coat then follow up with a nourishing conditioner for smooth, shiny fur.

Fact: Dogs should be groomed regularly.

Regular brushing with proper tools – sometimes as often as daily – is important. Not only can it help prevent matting in long-haired or double-coated dogs, it also stimulates blood flow to the skin, which helps keep it healthy, and ensures you notice any changes in your pet’s skin and coat. Grooming should also include cleaning ears, brushing teeth and trimming nails.

Fiction: Poor hydration does not affect skin or coat.

Fresh, clean water is essential for all bodily functions, including the maintenance of healthy skin. To help keep dogs hydrated, be sure fresh water is available to them, particularly at mealtimes.

Fact: Flea and tick control is essential for healthy skin and shiny coats.

If not controlled, fleas and ticks can wreak havoc on skin, which in turn affects coat quality. The irritation they cause typically promotes excessive scratching and licking.

Fiction: Dogs don’t need to use pet shampoo.

Human skin and hair are different from the skin and fur of dogs and should be treated as such. Shampoo designed for humans can strip oils and lead to dryness when used on dogs, which can result in infections and skin irritations. Be sure to use a shampoo specifically formulated for pets to maintain skin and coat health.

Fact: A high-quality, balanced pet food recipe is key to healthy skin and a shiny coat.

Because every dog is different and has varied energy requirements, the right blend of ingredients – rather than any one specific ingredient – tailored for individual dogs can help achieve healthy skin and shiny coats. For example, recipes like Go! Solutions Skin + Coat Care Large Breed Puppy and Adult Salmon Recipes with Grains are tailor-made for large breed puppies and adults with single-source animal protein from salmon to help build strong muscles; Omega fatty acids to support healthy, hydrated skin and a shiny coat; and the proper balance of nutrients to meet the unique needs of large breed dogs throughout their life stages.

To learn more about recipes that promote healthy skin and shiny coats, visit go-solutions.com.

Continue Reading

Pet Care

Size matters: How body size shapes dogs’ aging patterns

Smaller dogs may live twice as long life as their larger counterparts. But does this size difference also impact how dogs age in terms of behavior and cognitive abilities?

Published

on

Smaller dogs may live twice as long life as their larger counterparts. But does this size difference also impact how dogs age in terms of behavior and cognitive abilities? Based on the data of 15,000 dogs, researchers from ELTE Eötvös Loránd University, Budapest, found that larger dogs experience an earlier onset of age-related decline (at around seven-eight years of age versus ten-eleven years in smaller dogs), but also a slower decline rate compared to smaller dogs. Additionally, the study also points out that, although larger dogs have somewhat shorter lifespans, they also maintain their cognitive health longer and experience a smaller degree of age-related decline than their smaller counterparts.

The average life expectancy of dogs varies more than two-fold between breeds, with giant dogs generally living to seven years and small dogs to fourteen. Purebreds also have a shorter life span than mixed breeds. However, little is known about how life expectancy is related to age-related behavioral and cognitive decline. In a study published in GeroScience, researchers from ELTE Eötvös Loránd University, Budapest, explored the intriguing connection between a dog’s size and its aging process.  

The researchers collected data from over 15,000 dogs and assessed the age trajectories of various behavioral characteristics and the prevalence of canine cognitive dysfunction. They investigated at what age the behavioral and cognitive changes start, how fast the changes progress, and also examined factors like the dog’s body size, head shape, purebred status in relation to these age-related changes.

According to the results, behavioral and cognitive aging in dogs begin around ten and a half years of age, but the onset of aging, as well as the aging rate depend on the body size of the dogs. Dogs weighing over thirty kilogram (66 lbs) show an earlier onset of age-related decline by two-three years, but the rate of decline is slower compared to smaller dogs. “Larger dogs experience a physical breakdown at an earlier age, and the accumulating illnesses, and degradation in sensory functions leads to ‘old age behaviors’ long before their mental decline would begin.” – explained Borbála Turcsán, first author of the study.

On the other hand,

dogs weighing less than approximately seven kilogram (14 lbs) exhibited over four times higher prevalence of cognitive decline in old age than larger dogs, supporting the idea that although larger dogs have a shorter lifespan, they also experience a more limited degree of cognitive decline.

Unexpectedly, long-nosed (dolichocephalic) dogs, such as greyhounds, and purebreds have a higher risk of developing cognitive decline in old age compared to meso- and brachycephalic dogs and mixed-breeds. 

One of the most interesting findings of the study was that owners started to consider their dogs “old” around the age of six, regardless of the size of the dog or its purebred status. “Owners consider their dogs “old’ four to five years earlier than would be expected from behavioral data. This may be due to graying and barely noticeable changes,” explained Enikő Kubinyi, Head of the Senior Family Dog Project.

The new research highlights that body size not only influences a dog’s life expectancy, but also its healthspan.

However, the effect is not gradual, as only extreme size groups, the very small (toy) or very large (giant) dogs have markedly different aging trajectories. “For those who want a smaller sized dog but do not want to risk severe mental health problems in old age or want a larger sized dog but do not want to risk physical health problems at 7-8 years of age, we recommend a dog from the 10-30 kg size range.”  – explained Turcsán. “Based on our results, these dogs have a longer healthspan relative to their expected lifespan than their smaller and larger counterparts.”

Continue Reading
Advertisement
Advertisement

Like Us On Facebook

Facebook Pagelike Widget

Most Popular

Copyright ©FRINGE PUBLISHING. All rights reserved.