{"id":7942,"date":"2022-08-08T12:37:43","date_gmt":"2022-08-08T04:37:43","guid":{"rendered":"http:\/\/zestmag.com\/online\/?p=7942"},"modified":"2022-08-08T12:37:44","modified_gmt":"2022-08-08T04:37:44","slug":"down-on-vitamin-d-it-could-be-the-cause-of-chronic-inflammation","status":"publish","type":"post","link":"http:\/\/zestmag.com\/online\/down-on-vitamin-d-it-could-be-the-cause-of-chronic-inflammation\/","title":{"rendered":"Down on Vitamin D? It could be the cause of chronic inflammation"},"content":{"rendered":"\n

Inflammation is\u00a0an essential part of the body’s healing process. But when it persists, it can contribute to a wide range of complex diseases including type 2 diabetes, heart disease, and autoimmune diseases.<\/strong><\/p>\n\n\n\n

Now,\u00a0world-first genetic research<\/a>\u00a0from the\u00a0University of South Australia\u00a0shows a direct link between low levels of vitamin D and high levels of inflammation, providing an important biomarker to identify people at higher risk of or severity of chronic illnesses with an inflammatory component.<\/p>\n\n\n\n

The study examined the genetic data of 294\u200a,970 participants in the\u00a0UK Biobank, using\u00a0Mendelian randomization\u00a0to show the association between vitamin D and C-reactive protein levels, an indicator of inflammation.<\/p>\n\n\n\n

Lead researcher, UniSA\u2019s\u00a0Dr Ang Zhou, says the findings suggest that boosting\u00a0vitamin D\u00a0in people with a deficiency may reduce chronic inflammation.<\/p>\n\n\n\n

\u201cInflammation is your body’s way of protecting your tissues if you’ve been injured or have an infection,\u201d Dr Zhou says. \u201cHigh levels of C-reactive protein are generated by the liver in response to inflammation, so when your body is experiencing chronic inflammation, it also shows higher levels of\u00a0C-reactive protein. This study examined vitamin D and C-reactive proteins and found a one-way relationship between low levels of vitamin D and high levels of C-reactive protein, expressed as inflammation. Boosting vitamin D in people with deficiencies may reduce chronic inflammation, helping them avoid a number of related diseases.\u201d<\/p>\n\n\n\n

Supported by the\u00a0National Health and Medical Research Council\u00a0and published in the\u00a0International Journal of Epidemiology\u00a0the study also raises the possibility that having adequate vitamin D concentrations may mitigate complications arising from obesity and reduce the risk or severity of chronic illnesses with an inflammatory component, such as CVDs, diabetes, and autoimmune diseases.<\/p>\n\n\n\n

Senior investigator and Director of UniSA\u2019s\u00a0Australian Centre for Precision Health,\u00a0Professor Elina Hypp\u00f6nen, says these results are important and provide an explanation for some of the controversies in reported associations with vitamin D.<\/p>\n\n\n\n

\u201cWe have repeatedly seen evidence for health benefits for increasing vitamin D concentrations in individuals with very low levels, while for others, there appears to be little to no benefit.\u201d Prof Hypp\u00f6nen says.\u00a0 \u201cThese findings highlight the importance of avoiding clinical vitamin D deficiency, and provide further evidence for the wide-ranging effects of hormonal vitamin D.\u201d<\/p>\n","protected":false},"excerpt":{"rendered":"

Lead researcher, UniSA\u2019s Dr Ang Zhou, says the findings suggest that boosting vitamin D in people with a deficiency may reduce chronic inflammation.<\/p>\n","protected":false},"author":3,"featured_media":7010,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[4],"tags":[1463,1382,1019],"class_list":["post-7942","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-newsmakers","tag-multivitamin","tag-vitamin-d","tag-vitamins"],"_links":{"self":[{"href":"http:\/\/zestmag.com\/online\/wp-json\/wp\/v2\/posts\/7942","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/zestmag.com\/online\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/zestmag.com\/online\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/zestmag.com\/online\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"http:\/\/zestmag.com\/online\/wp-json\/wp\/v2\/comments?post=7942"}],"version-history":[{"count":1,"href":"http:\/\/zestmag.com\/online\/wp-json\/wp\/v2\/posts\/7942\/revisions"}],"predecessor-version":[{"id":7943,"href":"http:\/\/zestmag.com\/online\/wp-json\/wp\/v2\/posts\/7942\/revisions\/7943"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/zestmag.com\/online\/wp-json\/wp\/v2\/media\/7010"}],"wp:attachment":[{"href":"http:\/\/zestmag.com\/online\/wp-json\/wp\/v2\/media?parent=7942"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/zestmag.com\/online\/wp-json\/wp\/v2\/categories?post=7942"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/zestmag.com\/online\/wp-json\/wp\/v2\/tags?post=7942"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}