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Curtailed sleep may alter how intense exercise stresses the heart

Previous epidemiological studies have demonstrated that, at the population level, chronically disrupted and shortened sleep increases the risk of several cardiovascular diseases, such as high blood pressure and myocardial infarction.

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In a new study, participants underwent an intense bout of exercise after both normal sleep and after three nights of curtailed sleep. When they exercised after curtailed sleep, the levels of the heart injury biomarker troponin increased slightly more, compared with when the participants performed exercise in their well-rested condition. The study is a smaller pilot study and it is not yet possible to determine if the findings may be of relevance for cardiovascular health. The study is published in the journal Molecular Metabolism.

Previous epidemiological studies have demonstrated that, at the population level, chronically disrupted and shortened sleep increases the risk of several cardiovascular diseases, such as high blood pressure and myocardial infarction. In contrast, physical exercise can reduce the risk of cardiovascular disease. However, it has been unknown whether controlled sleep restriction can modulate cardiac stress during strenuous exercise.

“Exercise is great for the heart, while lack of sleep can adversely impact the cardiovascular system. But it has been unknown whether shortened sleep can modulate the physiologic stress that intense exercise seems to have on the cells of the heart,” says Jonathan Cedernaes, physician and associate professor of medical cell biology at Uppsala University, who led the study.

A specific type of the protein troponin is found in the heart’s muscle cells. Low amounts of troponin can be released after high-intensity training. Levels of troponin are routinely determined in the clinic, as significantly higher levels are seen in the setting of acute cardiovascular events.

“Higher blood levels of troponin after exercise have been linked to a relative increased prospective risk of cardiovascular diseases. It is not really known what the mechanism is, but at the same time, we know that one’s cardiovascular health is modulated through an interplay of lifestyle factors. We therefore thought it would be important to investigate whether the release of troponin during exercise can be affected by sleep restriction. One reason is the fact that many occupations entail work that disrupts sleep, such as for healthcare workers,” says Cedernaes.

Previous studies have found that exercise can counteract certain adverse effects of curtailed sleep on metabolism. Furthermore, data at the population level indicate that exercise can counteract the negative effects of chronic sleep loss on the cardiovascular system.

“Those who report exercising on a regular basis, but get less sleep than the ideal amount, still reduce their risk of dying from cardiovascular disease. At the same time, we know that chronic or recurrent sleep disruption is bad for cardiovascular health. It is therefore possible that a more pronounced lack of sleep in the long run can increase the relative risk that the heart is injured in some way by more intense exercise. But many individuals experience a temporary lack of sleep, and the need for sleep is also very individual,” Cedernaes points out. “The epidemiological evidence related to disturbed sleep per se, applies primarily to chronic lack of sleep and long-term shift work, and are seen when averaging at the population level.”

16 young men, healthy and normal-weight, underwent the study. All were extensively screened for previous cardiovascular disease, as well as for heredity for such conditions. In addition, all participants had normal sleeping habits within the recommended range – that is, they reported getting 7-9 hours of sleep on a regular basis.

The participants were monitored in a sleep laboratory, where their meal and activity schedules were standardized. In one of the two sessions, participants got a normal amount of sleep, three nights in a row. During their other session, the participants were kept awake for half the nights, three nights in a row. On each occasion, blood samples were taken in the evening and in the morning. After both sleep interventions, blood samples were also taken on the last day, both before and after a 30-min-long intense stationary cycling session.

The researchers measured two biomarkers in the blood samples. NT-proBNP reflects the load on the heart. The second protein, troponin, is commonly used as a marker of cardiac injury. The results showed that the levels of NT-proBNP increased in response to exercise, but this increase did not differ depending on the amount of sleep. Blood levels of troponin also increased after the workout. However, for troponin, the increase after exercise was almost 40% higher after three nights of partial sleep restriction, compared with after three nights of normal sleep.

“An important observation was that the levels of troponin and NT-proBNP were not elevated in response to sleep restriction at any time prior to the workout. It is possible that lack of sleep may instead lower the threshold at which an increased exercise load results in measurable stress in heart muscle cells, as may occur in response to strenuous exercise,” says Cedernaes. “However, we noted that the increase in circulating troponin levels following exercise was variable across individuals. Previous research under resting conditions has also hinted at such variability, and it would be interesting to uncover the mechanisms.”

Cedernaes continues: “Today there is no evidence to suggest that it would be harmful to the heart if you exercise regularly when you have slept too little. One can instead turn the argument around: by ensuring that one gets enough sleep, one may further increase the positive impact of physical exercise. While we know that high-intensity training generally has benefits in the long run, our results may be worth considering and exploring in specific groups of individuals. Examples include athletes and the military. These groups may be required to perform at extreme physical levels even under conditions of curtailed sleep. It may be good to further consider the importance of sleep in these contexts, especially as we also know that improving sleep can also improve one’s performance, both cognitively and physically.”

One limitation of the current study was that only 16 individuals were included. The study should be considered as a pilot study that requires further validation and follow up. Such studies are also needed to examine if these changes also apply to other age groups or women.

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Bookshelf PH announces book collections from diverse genres

Publishing house Bookshelf PH, with its collection of books from diverse genres, has heart-swooning reads that touch all five love languages.

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Love is given, felt, and explored in ways we never expect.

We’re no strangers to the concept of feeling kilig, an emotion that makes hearts swoon and flutter whenever we give or receive love. Speaking of giving and receiving love, we might prefer one over the other but overall, these five love languages create a holistic relationship with our loved ones whether that’s through physical touch, words of affirmation, quality time, gift-giving, or acts of service.

Publishing house Bookshelf PH, with its collection of books from diverse genres, has heart-swooning reads that touch all five love languages. From affirming poems to small acts of service, here are five books that explore love’s different manifestations, each with stories to tell of how we can give and receive love in ways we prefer the most.

1. Jasmines in Her Hair – Words of Affirmation

Love is expressed through the gentle whisper of words. ”Jasmines in Her Hair” by Kalpesh Desai is a poetry collection that features the themes and facets of love. From tender beginnings of infatuation to depths of enduring connection, each poem will captivate readers to immerse themselves in passionate sensibilities found in delight, sorrow, grief, acceptance, and resilience, capturing the essence of the heart’s universal experiences. 

Poetic words are as powerful as daily communication and this book might be the perfect bond for lovers. If you love compliments, notes, or sweet whispers, then words of affirmation may be your cup of love language. It’s not too old-school to write personal notes inspired by these poems to show appreciation to your Lovey-dovey.

2. Laws of Motions and Attraction – Physical Touch

“Alex never believed in love at first sight. But right then she realized, maybe she had loved him all along. It had been a long time coming, but it turned out ‘maybe someday’ was worth the wait, after all..”

Missing those back hugs and forehead kisses? How about those tender traces of his fingertips to your cheeks? Just when you know that physical touch becomes a language of its own, it speaks volume where words fall short. This is your sign to reminisce about the past and reflect if he is worth the second chance.

Gravitate your senses with Kaye Allen’s contemporary romance novel, “Laws of Motions and Attraction” as it brings you the story of Alex, a driven student who finds herself captivated by the most ideal suitor on campus only to discover that destiny has other plans. In this enthralling examination of love, accompany Alex on a journey fraught with twists and turns, and let her story touch your heart brimming every moment with sweet affection.

3. Warm Blankets in Cold Midnights – Gift-Giving

Who says love month is over? February may have passed but it’s never late to surprise someone with a thoughtful present. Let your cozy affection be felt by giving Warm Blankets in Cold Midnights to express the language of gift-giving!

Share the warmth with your loved one as you immerse in Janella Ventura’s short story collection, “Warm Blankets in Cold Midnights,” featuring 23 heartwarming love stories to uplift your spirits and 18 tear-jerking tales that will leave you deeply moved. From handmade treasures to heartfelt gestures,  Warm Blankets in Cold Midnights reminds readers that the true value of a gift lies not in its material worth, but in the love and care with which it is given.

4. Words, Fate, and Accidents – Quality Time

“…We may not know each other well but sometimes people could find comfort in the most unlikely places. Be it in a good book, a playlist with all favorite songs, or even in a foreign country, standing beside a stranger you met by accident.”

Another heart-touching craft from Kaye Allen is her “Words, Fate, and Accidents”, which is a story of connection and companionship. In a world where time is fleeting and fate is unpredictable, two strangers found solace in each other’s company, forging bonds that withstand the test of time. If you value quality time for your loved ones, then this book might remind you that time isn’t measured in minutes or hours, but in the profound moments shared between kindred spirits.

5. Lost You, Found Me – Acts of Service

“Lost is a state we will perpetually be in and the life is best approached by embracing it as it is.”

Picture this: late-night study sessions, surprise coffee deliveries, and shoulder-to-cry-on moments. Everyone has been through the rough stage between college and adulting where those small acts of service matter most in times when we feel most alone. You’re not lost sweetie, because a story that resonates has found its way to you!

Testament to the power of selfless devotion, Zara Carbonell’s “Lost You, Found Me” takes  readers into the tumultuous journey of love, loss, and self-discovery—a celebration of love through acts of sacrifice. Set against the backdrop of the exhilarating transition from college into the unknowns of adulthood, Lost You, Found Me offers a unique perspective on the exploration of life’s nitty-gritty.

Each of these books provides a fresh view on the languages of love and illustrates the diverse ways we communicate and receive affection. Whether through verbal affection, intimate gestures, shared warmth of hugs, or acts of selflessness, these authors capture the universality of love–transcending barriers and resonating deeply within our beings.

Thrilled to grab a copy of one of these books that pulsates your love language?

Visit Bookshelf PH  and discover the perfect read for you.

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Filipinos can now gain easier access to insurance with SeaInsure and Igloo

Filipinos can now easily access various personal and family insurance plans from SeaInsure Philippines through Igloo Philippines’ AI-powered app, Ignite by Igloo.

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Filipinos can now easily access various personal and family insurance plans from SeaInsure Philippines through Igloo Philippines’ AI-powered app, Ignite by Igloo.

The partnership between the two companies brings greater convenience and empowerment to insurance providers and seekers, giving Filipinos wider accessibility to essential insurance plans and supporting financial resilience.The initial products available on the app provide up to  ₱300,000 worth of coverage.

These include the SeaInsure Junior Accident Shield (0 to 17 years old), which covers medical expenses resulting from accidents; the SeaInsure Ladies Accident Shield (18 to 45 years old), which provides general accident coverage, including beauty procedures and pregnancy complications; SeaInsure Personal Accident Shield (18 to 60 years old) that takes care of medical expenses from unfortunate accidents; and SeaInsure Senior Accident Shield (61 to 70 years old) that protects from accidents like slips and bone fractures.

For more information, visit https://seainsure.com.ph/products/personal/protection.

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PRUBabies receives back-to-back international awards

ru Life UK offered 175,000 free vouchers of PRUMedCare – Select Infectious Diseases coverage for newborns from 7 days to 11 months old, helping parents protect their newborns against the cost of getting sick from any of the covered four infectious diseases – Dengue, Typhoid, Measles and Malaria.

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PRUBabies, Pru Life UK’s free insurance coverage against select infectious diseases for newborns, bagged Silver and Bronze Stevie®Awardsfor Community Relations/Public Service Communications and Innovative Achievement in Diversity & Inclusion, respectively.

As a testament to the company’s commitment to driving financial inclusion in the country, Pru Life UK offered 175,000 free vouchers of PRUMedCare – Select Infectious Diseases coverage for newborns from 7 days to 11 months old, helping parents protect their newborns against the cost of getting sick from any of the covered four infectious diseases – Dengue, Typhoid, Measles and Malaria. 

“Daghang salamat Pru Life UK. Dahil sa inyo, nabigyan ng libreng proteksyon ang aking baby,” shares Jeresa Caranoo, mother from Bantayan Island, Cebu who received free insurance for her child. 

Through PRUBabies, parents can receive cash assistance for the diagnosis and death of newborns due to any of the four covered diseases. The Department of Health has warned the public to watch out for the four covered diseases, particularly during summer. 

The life insurer distributed free vouchers across the country through Pru Life UK’s 42,000-strong agency force and the support of local government units, non-government organizations (NGOs) and hospitals – NGO Asia Society for Social Improvement and Sustainable Transformation (ASSIST) for Bantayan Island, Cebu and Parañaque City; The CSR arm of FirstGen Corp. for its host communities in Batangas City; St. Scholastica’s Formation House in Tagaytay City; Philippine Medical Association-Calamba for Dr. Jose P. Rizal District Hospital in Calamba, Laguna; Rotary Club of Mandaluyong-Biyaya for the Grace to Be Born Shelter in Pasig City; Microfinance NGO Tulay sa Pag-unlad Inc. (TSPI) in Makati; Office of Palawan Board Member Anton Alvarez and the Mayor’s Office of Taytay for Taytay, Palawan, Rotary Club of Mandaluyong and Mandaluyong City government for the Mandaluyong City Medical Center, Manila City government for Tondo, Manila, and Barangay Council of Tandang Sora for Barangay Tandang Sora in Quezon City.

A combined financial literacy and climate & health session was also conducted for the families in Palawan, the only province in the Philippines with known malaria cases. 

PRUBabies is one of the many ways we make life insurance more accessible to more Filipino families, including babies who deserve to be protected from birthWe are grateful to our like-minded partners for their support in reaching out to unserved and underserved communities in far-flung areas. With PRUBabies, we live up to our mission to be the most trusted partners for every life and protectors for every future of Filipino families,” shares Allan Tumbaga, Pru Life UK’s Chief Customer and Marketing Officer. The free coverage vouchers have been distributed in 2023. Filipinos who want to be continuously financially protected with PRUMedCare – Select Infectious Diseases can get it via Pulse app.

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