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Chronic loneliness may increase stroke risk among older adults

When loneliness was assessed at baseline only, the participants considered lonely had a 25% higher risk of stroke than those not considered lonely. Among the participants who reported loneliness at two time points, those in the “consistently high” group had a 56% higher risk of stroke than those in the “consistently low” group, even after accounting for a broad range of other known risk factors.

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Chronic loneliness may significantly raise older adults’ risk of stroke, according to a new study led by Harvard T.H. Chan School of Public Health. 

“Loneliness is increasingly considered a major public health issue. Our findings further highlight why that is,” said lead author Yenee Soh, research associate in the Department of Social and Behavioral Sciences. “Especially when experienced chronically, our study suggests loneliness may play an important role in stroke incidence, which is already one of the leading causes of long-term disability and mortality worldwide.”

While previous research has linked loneliness to higher risk of developing cardiovascular diseases, few have examined the impact on stroke risk specifically. This study is one of the first to examine the association between loneliness changes and stroke risk over time.

Using 2006-2018 data from the Health and Retirement Study (HRS), the researchers assessed the association between changes in loneliness and stroke incidence over time. During 2006-2008, 12,161 participants—all adults ages 50 and above who never had a stroke—responded to questions on the Revised UCLA Loneliness Scale, from which the researchers created summary loneliness scores. Four years later (2010-2012), 8,936 participants who remained in the study responded to the same questions again. The researchers then placed the participants into one of four groups according to their loneliness scores across the two time points: “consistently low” (those who scored low on the loneliness scale at both baseline and follow-up); “remitting” (those who scored high at baseline and low at follow-up); “recent onset” (those who scored low at baseline and high at follow-up); and “consistently high” (those who scored high at both baseline and follow-up).

Among the participants whose loneliness was measured at baseline only, 1,237 strokes occurred during the follow-up period (2006-2018). Among the participants who provided two assessments of loneliness over time, 601 strokes occurred during the follow-up period (2010-2018). The researchers analyzed each group’s risk of stroke over the follow-up period in the context of their experiences with loneliness, controlling for other health and behavioral risk factors. These included social isolation and depressive symptoms, which are closely related but distinct from loneliness.

The findings showed a link between loneliness and higher risk of stroke and found that chronic loneliness heightened risk the most. When loneliness was assessed at baseline only, the participants considered lonely had a 25% higher risk of stroke than those not considered lonely. Among the participants who reported loneliness at two time points, those in the “consistently high” group had a 56% higher risk of stroke than those in the “consistently low” group, even after accounting for a broad range of other known risk factors. While the baseline analyses suggest loneliness at one time point was associated with higher risk, those who experienced remitting or recent onset loneliness did not show a clear pattern of increased risk of stroke—suggesting that loneliness’ impact on stroke risk occurs over the longer term.

“Repeat assessments of loneliness may help identify those who are chronically lonely and are therefore at a higher risk for stroke. If we fail to address their feelings of loneliness, on a micro and macro scale, there could be profound health consequences,” said Soh. “Importantly, these interventions must specifically target loneliness, which is a subjective perception and should not be conflated with social isolation.”

The authors noted that further research examining both nuanced changes in loneliness over the short-term, as well as loneliness patterns over a longer period of time, may help shed additional light on the loneliness-stroke association. They also noted that more research is needed to understand the potential underlying mechanisms, and that the study findings were limited to middle-aged and older adults and may not be generalizable to younger individuals.

Other Harvard Chan authors included Ichiro Kawachi, Laura Kubzansky, Lisa Berkman, and Henning Tiemeier.

Chronic Loneliness and the Risk of Incident Stroke in Middle and Late Adulthood: A Longitudinal Cohort Study of U.S. Older Adults” was written by Yenee Soh, Ichiro Kawachi, Laura D. Kubzansky, Lisa F. Berkman, Henning Tiemeier, and appeared in eClinicalMedicine.

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5 Tips to upgrade your sleep

Sleep contributes to better brain function, memory, concentration and lower stress. According to the National Institutes of Health, most adults need 7-9 hours of sleep every night to achieve maximum health benefits.

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Good sleep isn’t just about waking up feeling rested and ready for the day. Quality sleep, and plenty of it, is important for your overall health. While you sleep, your body naturally recharges itself, which puts you at lower risk for cardiovascular problems and chronic conditions like diabetes, as well as improving your immune system.

Sleep also contributes to better brain function, memory, concentration and lower stress. According to the National Institutes of Health, most adults need 7-9 hours of sleep every night to achieve maximum health benefits.

If you’re falling short of the recommended amount of sleep, you may be able to make some adjustments that help you reap the health benefits of better rest. Learn what you can do to improve your sleep with these tips from the experts in safer, healthier sleep at Naturepedic.

Reduce Light Exposure
Your body’s natural circadian rhythms are closely aligned with light and dark. When your body senses light, it sends signals to your brain that it’s time to be awake. Light also suppresses your body’s production of melatonin, a hormone linked to sleep. Cutting back on bright lights and avoiding devices at least an hour before bed can tell your body it’s time to wind down, and sleeping in a dark room promotes better rest.

Invest in the Right Mattress
Your mattress plays a major role in your comfort through the night, so making sure it fits your needs is an important step toward getting better rest. Take control of your comfort with a quality mattress such as Naturepedic’s EOS (Ergonomic Organic Sleep) mattress, which is handcrafted and made without polyurethane foam, formaldehyde, flame retardants or fiberglass. The breathable layers of certified organic cotton, wool and GOTS-approved latex ensure better temperature regulation while naturally contouring the body. An added feature is the ability to customize each side of the bed by opening the zippers and adjusting the layered components for the perfect comfort combination.

Find the Right Sheets
Sheets that are too stiff, scratchy or otherwise unpleasant make it nearly impossible to settle in for a good night’s rest. Higher thread counts tend to be softer, higher quality sheets. However, you may need to experiment to find which material suits you best.

Set a Comfortable Temperature
When you’re too hot or cold, your mind tends to focus on those sensations rather than allowing you to slip into a slumber. Set your thermostat at a comfortable temperature, adding fans or adjusting the layers of bedding as necessary to achieve the perfect level of cozy comfort.

Use a Sound Machine
If you’re a light sleeper, noise can wreak havoc on your rest. Many people find sound machines offer two key benefits: They provide a soothing sound, such as rain or ocean waves, that allows you to relax and ease into slumber and constant background noise, so additional sounds are less disruptive.

Find more solutions for achieving better sleep at Naturepedic.com.

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What you should know about IBD

Two common conditions are irritable bowel syndrome (IBS) and inflammatory bowel disease (IBD). They’re often confused for one another, but these are actually two different GI disorders.

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It may not be something you like to talk about, but if you have gastrointestinal (GI) problems, your symptoms may be far more common than you think. According to data from the American Gastroenterological Association, 60-70 million people living in the United States have gut health concerns.

Two common conditions are irritable bowel syndrome (IBS) and inflammatory bowel disease (IBD). They’re often confused for one another, but these are actually two different GI disorders.

IBS is a syndrome; it is defined by a group of symptoms, does not cause inflammation and rarely requires hospitalization or surgery. IBD, on the other hand, is an umbrella term used to describe disorders that cause chronic inflammation of your GI tract.

The disease is more common than you may realize; a study led by the Crohn’s & Colitis Foundation found nearly 1 in 100 people living in the U.S. have IBD. The two most common forms of IBD are Crohn’s disease and ulcerative colitis.

Understanding IBD Symptoms
Because it poses serious health risks and can cause permanent damage to your intestines, it’s important to be aware of what IBD is and recognize the symptoms. Your primary care doctor or gastroenterologist can help if you have concerns about these symptoms:

  • Intense, crampy pain that doesn’t go away in a day or two or has been present on and off for weeks or longer
  • A notable change in bowel movement frequency, whether more or less often
  • Frequent diarrhea over several weeks, or loose stools multiple times a day
  • Frequent constipation, or constipation alternating with diarrhea
  • Urgency on a regular basis or inability to hold back the bowel movement before reaching the bathroom
  • Blood with bowel movements
  • Mucus in your stool regularly or paired with pain or other symptoms
  • Always feeling as though you aren’t fully emptying your bowels

Other symptoms that may have a variety of causes but need extra attention especially if you notice them along with any of the symptoms above include pain outside of the gut, fatigue, loss of appetite and weight loss. In addition, children with IBD may have delays in growth and the onset of puberty.

Diagnosing IBD
No single test can confirm a Crohn’s or ulcerative colitis diagnosis. Your medical history and information obtained from diagnostic testing can exclude other potential causes of your symptoms, since gastrointestinal symptoms are common and can have a variety of causes.

Your first tests will likely include blood and stool laboratory tests. Further testing could include imaging studies of your gastrointestinal tract or a look inside your GI tract through an endoscope.

Identifying Treatment Options
Once an IBD diagnosis is confirmed, you can partner with your doctor to manage your disease. Treatment plans are highly personalized, as what works for one person may not for another. Medication and managing your diet and nutrition are two common treatment recommendations. In some cases, surgery can help improve your quality of life.

Clinical trials may also be an option for treating your IBD. Through clinical trials, researchers find new ways to improve treatments and quality of life. In fact, clinical trials represent the final stages of a long and careful research process to make new and improved treatment options for patients available.

However, an important part of clinical trials for IBD is patient participation. Without the enrollment of patients in clinical trials, new treatment options for IBD can be delayed or never become available.

Equally important to this process is having a diverse representation of patients that considers race, age or other categories. This helps researchers develop treatments that meet the needs of a vast IBD patient community.

If you’re interested in participating in a clinical trial, ask your doctor to help you find a trial that is right for you, and visit crohnscolitisfoundation.org to learn more about IBD and treatment options, including clinical trials.

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Unlocking the science of sleep: How rest enhances language learning

Getting eight hours of sleep every night helps the brain to store and learn a new language.

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Sleep is critical for all sorts of reasons, but a team of international scientists has discovered a new incentive for getting eight hours of sleep every night: it helps the brain to store and learn a new language.

A study led by the University of South Australia (UniSA) and published in the Journal of Neuroscience has revealed that the coordination of two electrical events in the sleeping brain significantly improves our ability to remember new words and complex grammatical rules.

In an experiment with 35 native English-speaking adults, researchers tracked the brain activity of participants learning a miniature language called Mini Pinyin that is based on Mandarin but with similar grammatical rules to English.

Half of the participants learned Mini Pinyin in the morning and then returned in the evening to have their memory tested. The other half learned Mini Pinyin in the evening and then slept in the laboratory overnight while their brain activity was recorded. Researchers tested their progress in the morning.

Those who slept performed significantly better compared to those who remained awake.

Lead researcher  Dr Zachariah Cross, who did his PhD at UniSA but is now based at Northwestern University in Chicago, says sleep-based improvements were linked to the coupling of slow oscillations and sleep spindles – brainwave patterns that synchronise during NREM sleep.

“This coupling likely reflects the transfer of learned information from the hippocampus to the cortex, enhancing long-term memory storage,” Dr Cross says.

“Post-sleep neural activity showed unique patterns of theta oscillations associated with cognitive control and memory consolidation, suggesting a strong link between sleep-induced brainwave co-ordination and learning outcomes.”

UniSA researcher Dr Scott Coussens says the study underscores the importance of sleep in learning complex linguistic rules.

“By demonstrating how specific neural processes during sleep support memory consolidation, we provide a new perspective on how sleep disruption impacts language learning,” Dr Coussens says. “Sleep is not just restful; it’s an active, transformative state for the brain.”

The findings could also potentially inform treatments for individuals with language-related impairments, including autism spectrum disorder (ASD) and aphasia, who experience greater sleep disturbances than other adults.

Research on both animals and humans shows that slow oscillations improve neural plasticity – the brain’s ability to change and adapt in response to experiences and injury.

“From this perspective, slow oscillations could be increased via methods such as transcranial magnetic stimulation to accelerate aphasia-based speech and language therapy,” Dr Cross says.

In future, the researchers plan to explore how sleep and wake dynamics influence the learning of other complex cognitive tasks.

“Understanding how the brain works during sleep has implications beyond language learning. It could revolutionize how we approach education, rehabilitation, and cognitive training.”

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